Comparison of the Backbone Dynamics of a Folded and an Unfolded SH3 Domain Existing in Equilibrium in Aqueous Buffer

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecules. 1. Theory and range of validity

1982 • 3,662 citations

Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecules

1982 • 2,524 citations

Backbone Dynamics of a Free and a Phosphopeptide-Complexed Src Homology 2 Domain Studied by 15N NMR Relaxation

1994 • 2,051 citations

Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecules. 2. Analysis of experimental results

1982 • 1,800 citations

Backbone dynamics of proteins as studied by nitrogen-15 inverse detected heteronuclear NMR spectroscopy: application to staphylococcal nuclease

1989 • 1,740 citations

Reaction Rates by Nuclear Magnetic Resonance

1958 • 1,561 citations

Rapid recording of 2D NMR spectra without phase cycling. Application to the study of hydrogen exchange in proteins

1989 • 1,395 citations

The Control of Protein Stability and Association by Weak Interactions with Water: How Do Solvents Affect These Processes?

1993 • 1,076 citations

An improved sequence for broadband decoupling: WALTZ-16

1983 • 1,021 citations

Sensitivity improvement in proton-detected two-dimensional heteronuclear correlation NMR spectroscopy

1991 • 931 citations

The importance of not saturating water in protein NMR. Application to sensitivity enhancement and NOE measurements

1993 • 891 citations

Backbone 1H and 15N resonance assignments of the N-terminal SH3 domain of drk in folded and unfolded states using enhanced-sensitivity pulsed field gradient NMR techniques

1994 • 648 citations

Intramolecular motions of a zinc finger DNA-binding domain from Xfin characterized by proton-detected natural abundance carbon-13 heteronuclear NMR spectroscopy

1991 • 566 citations

Pulse sequences for removal of the effects of cross correlation between dipolar and chemical-shift anisotropy relaxation mechanisms on the measurement of heteronuclear T1 and T2 values in proteins

1992 • 475 citations

NMR Determination of Residual Structure in a Urea-Denatured Protein, the 434-Repressor

1992 • 449 citations

Analysis of the backbone dynamics of interleukin-1.beta. using two-dimensional inverse detected heteronuclear nitrogen-15-proton NMR spectroscopy

1990 • 432 citations

A heteronuclear correlation experiment for simultaneous determination of 15N longitudinal decay and chemical exchange rates of systems in slow equilibrium

1994 • 430 citations

Spin Echo Measurements of Nuclear Spin Coupling in Molecules

1952 • 427 citations

Mapping of spectral density functions using heteronuclear NMR relaxation measurements

1992 • 386 citations

Enhanced-Sensitivity Triple-Resonance Spectroscopy with Minimal H2O Saturation

1994 • 354 citations

Mapping of the spectral densities of nitrogen-hydrogen bond motions in Eglin c using heteronuclear relaxation experiments

1992 • 313 citations

A general method for assigning NMR spectra of denatured proteins using 3D HC(CO)NH-TOCSY triple resonance experiments

1993 • 297 citations

Spin-Lattice Relaxation Measurements in Slowly Relaxing Complex Spectra

1971 • 271 citations

Suppression of the effects of cross-correlation between dipolar and anisotropic chemical shift relaxation mechanisms in the measurement of spin-spin relaxation rates

1992 • 255 citations

Thermodynamic and Kinetic Analysis of the SH3 Domain of Spectrin Shows a Two-State Folding Transition

1994 • 252 citations

Determination of 15N chemical shift tensor via 15N-2H dipolar coupling in Boc-glycylglycyl[15N glycine]benzyl ester

1988 • 228 citations

Influence of cross-correlation between dipolar and anisotropic chemical shift relaxation mechanisms upon longitudinal relaxation rates of 15N in macromolecules

1990 • 196 citations

Backbone dynamics of the Bacillus subtilis glucose permease IIA domain determined from nitrogen-15 NMR relaxation measurements

1992 • 193 citations

Structural Characterization of the FK506 Binding Protein Unfolded in Urea and Guanidine Hydrochloride

1994 • 177 citations

Sensitivity improvement in proton-detected two-dimensional heteronuclear relay spectroscopy

1991 • 167 citations

Backbone dynamics of calcium-loaded calbindin D9k studied by two-dimensional proton-detected nitrogen-15 NMR spectroscopy

1992 • 166 citations

Effects of ion binding on the backbone dynamics of calbindin D9k determined by nitrogen-15 NMR relaxation

1993 • 151 citations

Kinetics of Folding of the All-β Sheet Protein Interleukin-1β

1993 • 148 citations

Denatured states of proteins and their roles in folding and stability

1993 • 132 citations

Minimizing Sensitivity Losses in Gradient-Selected 15N-1H HSQC Spectra of Proteins

1994 • 119 citations

Comparison of backbone and tryptophan side-chain dynamics of reduced and oxidized Escherichia coli thioredoxin using nitrogen-15 NMR relaxation measurements

1993 • 119 citations

Solvent suppression with symmetrically-shifted pulses

1993 • 115 citations

Partially Folded Conformation of the (30-51) Intermediate in the Disulphide Folding Pathway of Bovine Pancreatic Trypsin Inhibitor

1993 • 105 citations

Protein structure by solid-state NMR

1983 • 94 citations

Structures of SH2 and SH3 domains

1993 • 92 citations

Measurement of carbon-13 longitudinal relaxation using 1H detection

1987 • 89 citations

Dipolar nuclear spin relaxation of 19F in multispin systems. Application to 19F labeled proteins

1975 • 88 citations

Orientation of Peptide Fragments from Sos Proteins Bound to the N-Terminal SH3 Domain of Grb2 Determined by NMR Spectroscopy

1994 • 80 citations

Kinetics of the helix—coil transition of a polypeptide with non-ionic side groups, derived from ultrasonic relaxation measurements

1979 • 77 citations

Characterization of tHermotropic State Changes in Myosin Subfragment-1 and Heavy Meromyosin by UV Difference Spectroscopy

1989 • 70 citations

15N NMR Relaxation Studies of the FK506 Binding Protein: Dynamic Effects of Ligand Binding and Implications for Calcineurin Recognition

1994 • 70 citations

Nuclear magnetic resonance studies of the unfolding of pancreatic ribonuclease

1975 • 56 citations

Nitrogen-15 NMR relaxation studies of the FK506 binding protein: Backbone dynamics of the uncomplexed receptor

1993 • 55 citations