A study of the endogenous opioid system in the sudden infant death syndrome

The pharmacological basis of therapeutics

1981 • 2,853 citations

The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice

1980 • 705 citations

PROLONGED APNEA AND THE SUDDEN INFANT DEATH SYNDROME: CLINICAL AND LABORATORY OBSERVATIONS

1972 • 543 citations

THE DISTRIBUTION OF METHIONINE‐ENKEPHALIN AND LEUCINE‐ENKEPHALIN IN THE BRAIN AND PERIPHERAL TISSUES

1977 • 443 citations

Diminished Ventilatory Response to Hypoxia and Hypercapnia after Morphine in Normal Man

1975 • 345 citations

Stress-Induced Analgesia in Humans: Endogenous Opioids and Naloxone-Reversible Depression of Pain Reflexes

1981 • 329 citations

Heroin "Overdose" Death: Contribution of Drug-Associated Environmental Cues

1982 • 300 citations

Regulation of Respiration

1977 • 299 citations

Regional distribution of methionine-enkephalin and substance P-like immunoreactivity in normal human brain and in Huntington's disease

1980 • 289 citations

Bombesin, calcitonin and leu-enkephalin immunoreactivity in endocrine cells of human lung

1981 • 231 citations

Periodic Breathing in Infants With Near-Miss Sudden Infant Death Syndrome

1979 • 228 citations

Sudden Infant Death Syndrome: A Review of the Medical Literature 1974-1979

1980 • 228 citations

Ontogeny of opioid pharmacology and receptors: High and low affinity site differences

1981 • 217 citations

Met-enkephalin circulates in human plasma

1980 • 217 citations

Opiate Receptors in the Brain

1977 • 210 citations

Respiratory and cardiovascular effects of met-enkephalin applied to the ventral surface of the brain stem

1977 • 207 citations

Sudden Infant Death

1980 • 196 citations

Abnormal Regulation of Ventilation in Infants at Risk for Sudden-Infant-Death Syndrome

1977 • 194 citations

Pulmonary Arterial Abnormalities in the Sudden-Infant-Death Syndrome

1973 • 188 citations

Characteristics and function of opioids

1979 • 174 citations

Regional distribution of methionine-enkephalin- and beta-endorphin-like immunoreactivity in human brain and pituitary

1979 • 168 citations

Studies of the sudden infant death syndrome in King County, Washington. 3. Epidemiology.

1972 • 147 citations

SIDS and Near-SIDS

1982 • 145 citations

Radioimmunoassay of brain peptides: Evaluation of a methodology for the assay of β-endorphin and enkephalin

1977 • 140 citations

Sudden infant death syndrome among infants of drug-dependent mothers

1979 • 135 citations

Endorphins and the Control of Breathing

1981 • 134 citations

Plasma β-Endorphin and β-Lipotropin in the Human Fetus at Delivery: Correlation with Arterial pH and pO²*

1979 • 133 citations

Reflexes from the heart and lungs: physiological curiosities or important regulatory mechanisms

1978 • 124 citations

Effect of antenatal exposure to opiates on the development of opiate receptors in rat brain

1980 • 118 citations

β-endorphin: Effects on respiratory regulation

1978 • 114 citations

STUDIES OF THE SUDDEN INFANT DEATH SYNDROME IN KING COUNTY, WASHINGTON. III. EPIDEMIOLOGY

1972 • 113 citations

Deaths from narcotism in New York City. Incidence, circumstances, and postmortem findings.

1966 • 110 citations

STUDIES ON CIRCULATING MET‐ENKEPHALIN AND β‐ENDORPHIN: NORMAL SUBJECTS AND PATIENTS WITH RENAL AND ADRENAL DISEASE

1981 • 110 citations

Diurnal Rhythm of Plasma Immunoreactive β-Endorphin and Its Relationship to Sleep Stages and Plasma Rhythms of Cortisol and Prolactin*

1981 • 107 citations

Diminished hypoxic ventilatory responses in near-miss sudden infant death syndrome

1981 • 103 citations

Localization and Quantitation of <i>β</i>-Endorphin in Human Brain and Pituitary

1980 • 94 citations

Ontogenesis of enkephalinergic systems in rat brain: Post-natal changes in enkephalin levels, receptors and degrading enzyme activities

1980 • 94 citations

ABNORMAL HYPERCARBIC AND HYPOXIC SLEEP AROUSAL RESPONSES IN NEAR-MISS SIDS INFANTS

1981 • 87 citations

Hyper-Endorphin Syndrome in a Child with Necrotizing Encephalomyelopathy

1980 • 87 citations

Sudden Deaths in Infants Born to Methadone-Maintained Addicts

1972 • 87 citations

Regulation of Respiration

1977 • 83 citations

Stimulation of pulmonary J receptors by an enkephalin-analog.

1981 • 82 citations

Plasma Opioids in the First Hours of Life

1982 • 82 citations

Reflex effects following selective stimulation of J receptors in the cat.

1980 • 76 citations

β-Endorphin in human plasma: Basal and pathologically elevated levels

1979 • 73 citations

Pulmonary opiate receptor activation evokes a cardiorespiratory reflex

1982 • 73 citations

Generation and regulation of breathing in utero: fetal CO2 response test

1979 • 67 citations

beta-Endorphin central depression of respiration and circulation

1981 • 64 citations

Sleep Parameters and Respiratory Variables in ‘Near Miss’ Sudden Infant Death Syndrome Infants

1981 • 64 citations

Endogenous opiates and chemical control of breathing in humans.

1980 • 62 citations

Human pulmonary pathology associated with narcotic and other addictive drugs

1972 • 62 citations

Sudden unexpected death in infants of narcotic-dependent mothers

1978 • 61 citations

Study of naloxone in normal awake man: Effects on heart rate and respiration

1979 • 59 citations

Fatalities from narcotic addiction in New York City

1972 • 57 citations

Respiratory effects of ß-endorphin,d-Ala2-Met-enkephalinamide, and Met-enkephalin injected into the lateral ventricle and the pontomedullary subarachnoid space

1980 • 54 citations

(3H) Opiate binding: anomalous properties in kidney and liver membranes.

1978 • 53 citations

Deaths from Narcotism in New York City Incidence, Circumstances, and Postmortem Findings

1967 • 47 citations

SIDS and near-SIDS

1982 • 46 citations

Sudden apparently unexplained death during infancy. II. Pathologic findings in infants observed to die suddenly.

1953 • 43 citations

The sudden infant death syndrome: a review of recent advances.

1977 • 43 citations

DEATHS IN UNITED KINGDOM OPIOID USERS 1965-69

1970 • 37 citations

The Aetiology of the Sudden Infant Death Syndrome: Current Ideas on Breathing and Sleep and Possible Links to Deranged Thiamine Neurochemistry

1978 • 35 citations

SUDDEN INFANT DEATH SYNDROME

1972 • 31 citations

A study of 24-hour profiles of plasma met-enkephalin in man

1981 • 29 citations

Function and regulation of methionine5-enkephalin and its receptors in murine neuroblastoma cells.

1982 • 27 citations

Naloxone response in non-dependent man: Effect on six physiological variables

1980 • 22 citations

Pl�tzlicher, unerwarteter und ungekl�rter Tod im S�uglingsalter

1969 • 22 citations

Laryngeal Regulation of Airway Resistance

1980 • 20 citations

Endorphins, ventilatory control and sudden infant death syndrome — A review and synthesis

1981 • 19 citations

Idiopathic Adrenal Hypoplasia in Children

1972 • 18 citations

Transient Apnea after an Enkephalin Analogue in the Preterm Rabbit

1981 • 15 citations

THE PREPARATION OF FROZEN POULTRY: FACTORS RELATING TO THE PREVENTION OF STAPHYLOCOCCAL FOOD POISONING

1966 • 13 citations

SUDDEN, UNEXPECTED, AND UNEXPLAINED DEATH IN INFANTS

1969 • 13 citations

Pathophysiologic Mechanisms Causing Sleep Apnea and Hypoventilation in Infants

1980 • 13 citations

Sudden infant death due to congenital adrenal hypoplasia.

1977 • 13 citations

SUDDEN INFANT DEATHS: SOME CURRENT RESEARCH STRATEGIES

1979 • 13 citations

Neonatal and Infantile Apnea

1981 • 10 citations

THE SUDDEN INFANT DEATH SYNDROME

1980 • 6 citations