The Thyroid Transcription Factor 2 (TTF-2) Is a Promoter-Specific DNA-Binding Independent Transcriptional Repressor

The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary.

1996 • 1,208 citations

The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins

1993 • 619 citations

Follicular cells of the thyroid gland require Pax8 gene function

1998 • 610 citations

Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity.

1990 • 545 citations

PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis

1998 • 498 citations

Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland

1990 • 479 citations

Localization of Epidermal Growth Factor-stimulated Ras/Raf-1 Interaction to Caveolae Membrane

1996 • 449 citations

Mutation of the gene encoding human TTF-2 associated with thyroid agenesis, cleft palate and choanal atresia

1998 • 420 citations

A thyroid-specific nuclear protein essential for tissue-specific expression of the thyroglobulin promoter.

1989 • 382 citations

A mouse model for hereditary thyroid dysgenesis and cleft palate

1998 • 326 citations

Active repression mechanisms of eukaryotic transcription repressors

1996 • 308 citations

Pax-8, a paired domain-containing protein, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters.

1992 • 298 citations

TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation

1997 • 268 citations

The Paired-Domain Transcription Factor Pax8 Binds to the Upstream Enhancer of the Rat Sodium/Iodide Symporter Gene and Participates in Both Thyroid-Specific and Cyclic-AMP-Dependent Transcription

1999 • 255 citations

The Drosophila sloppy paired locus encodes two proteins involved in segmentation that show homology to mammalian transcription factors.

1992 • 233 citations

Expression of hepatic transcription factors during liver development and oval cell differentiation.

1994 • 230 citations

The Extracellular Matrix Coordinately Modulates Liver Transcription Factors and Hepatocyte Morphology

1991 • 224 citations

Cell-Type-Specific Expression of the Rat Thyroperoxidase Promoter Indicates Common Mechanisms for Thyroid-Specific Gene Expression

1992 • 210 citations

Repression versus activation in the control of gene transcription

1994 • 187 citations

, a Winged Helix Transcriptional Repressor with Expression Restricted to Embryonic Stem Cells

1996 • 167 citations

Extracellular signals that regulate liver transcription factors during hepatic differentiation in vitro.

1991 • 167 citations

The extracellular matrix coordinately modulates liver transcription factors and hepatocyte morphology.

1991 • 138 citations

Control of transcription by Krüppel through interactions with TFIIB and TFIIEβ

1995 • 134 citations

Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression.

1992 • 122 citations

Redundant Domains Contribute to the Transcriptional Activity of the Thyroid Transcription Factor 1

1995 • 111 citations

Insulin and insulin-like growth factor I regulate a thyroid-specific nuclear protein that binds to the thyroglobulin promoter.

1992 • 109 citations

The tissue‐specific expression of the thyroglobulin gene requires interaction between thyroid‐specific and ubiquitous factors

1990 • 94 citations

The Transcriptional Repressor Even-skipped Interacts Directly with TATA-Binding Protein

1995 • 93 citations

The hepatocyte nuclear factor-3/forkhead transcription regulatory family in development, inflammation, and neoplasia

1995 • 86 citations

Forced expression of Genesis, a winged helix transcriptional repressor isolated from embryonic stem cells, blocks granulocytic differentiation of 32D myeloid cells

1998 • 25 citations