Mutation of the gene encoding human TTF-2 associated with thyroid agenesis, cleft palate and choanal atresia

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary.

1996 • 1,208 citations

Five years on the wings of fork head

1996 • 657 citations

Follicular cells of the thyroid gland require Pax8 gene function

1998 • 610 citations

Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity.

1990 • 545 citations

PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis

1998 • 498 citations

Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland

1990 • 479 citations

A mouse model for hereditary thyroid dysgenesis and cleft palate

1998 • 326 citations

Pax-8, a paired domain-containing protein, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters.

1992 • 298 citations

TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation

1997 • 268 citations

Familial congenital hypothyroidism due to inactivating mutation of the thyrotropin receptor causing profound hypoplasia of the thyroid gland.

1997 • 255 citations

Genetic analysis of 29 kindreds with generalized and pituitary resistance to thyroid hormone. Identification of thirteen novel mutations in the thyroid hormone receptor beta gene.

1994 • 232 citations

Thyroid Hormone Action IN VITRO CHARACTERIZATION OF SOLUBILIZED NUCLEAR RECEPTORS FROM RAT LIVER AND CULTURED GH1 CELLS

1974 • 229 citations

Cell-Type-Specific Expression of the Rat Thyroperoxidase Promoter Indicates Common Mechanisms for Thyroid-Specific Gene Expression

1992 • 210 citations

Thyroid Hormone Regulates the Mouse Thyrotropin β-Subunit Gene Promoter in Transfected Primary Thyrotropes

1989 • 203 citations

Identification of a point mutation in the thyrotropin receptor of the hyt/hyt hypothyroid mouse.

1994 • 182 citations

Thyroid-specific enhancer-binding protein (T/EBP): cDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1.

1991 • 133 citations

Congenital hypothyroidism, spiky hair, and cleft palate.

1989 • 129 citations

Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression.

1992 • 122 citations

Congenital hypothyroidism detected by neonatal screening: relationship between biochemical severity and early clinical features.

1992 • 99 citations

Population study of congenital hypothyroidism and associated birth defects, Atlanta, 1979-1992

1997 • 97 citations

Survey of neonatal screening for primary hypothyroidism in England, Wales, and Northern Ireland 1982-4

1988 • 91 citations

Mutations in the Gene EncodingThyroid Transcription Factor-1 (TTF-1) Are Not a Frequent Cause of Congenital Hypothyroidism (CH) with Thyroid Dysgenesis

1997 • 80 citations

Absence of Mutations in the Gene EncodingThyroid Transcription Factor-1 (TTF-1) in Patients with Thyroid Dysgenesis

1997 • 72 citations

Identification of a cis-regulatory element and a thyroid-specific nuclear factor mediating the hormonal regulation of rat thyroid peroxidase promoter activity.

1993 • 59 citations

FKHL15,a New Human Member of the Forkhead Gene Family Located on Chromosome 9q22

1997 • 58 citations

Genetic and linkage analysis of familial congenital hypothyroidism: exclusion of linkage to the TSH receptor gene

1997 • 34 citations