Deoxyribonucleoside Triphosphates in Human Cells: Changes in Disease and Following Exposure to Drugs

Comparison of the Sensitivity of Normal Hematopoietic and Transplanted Lymphoma Colony-Forming Cells to Chemotherapeutic Agents Administered <italic>In Vivo</italic><xref ref-type="fn" rid="FN2">2</xref>

1966 • 537 citations

Experimental evaluation of potential anticancer agents VIII. Effects of certain nitrosoureas on intracerebral L1210 leukemia.

1963 • 369 citations

Effects of Hydroxyurea and 1‐β‐D‐Arabinofuranosyl‐cytosine on Deoxyribonucleotide Pools in Mouse Embryo Cells

1971 • 280 citations

Treatment of leukemia with large doses of methotrexate and folinic acid: clinical-biochemical correlates

1969 • 234 citations

Maturation-stimulation effect of brain extract and dibutyryl cyclic AMP on dissociated embryonic brain cells in culture.

1973 • 211 citations

A method for the determination of dATP and dTTP in picomole amounts

1970 • 206 citations

Deoxyribonucleotide Pools and Deoxyribonucleic Acid Synthesis in Cultured Mouse Embryo Cells

1970 • 161 citations

A rapid quantitative determination of deoxyribonucleoside triphosphates based on the enzymatic synthesis of DNA

1969 • 157 citations

Cell killing studies on the mode of action of methotrexate on L-cells in vitro.

1969 • 132 citations

Deoxyribonucleoside triphosphate pools in synchronized and drug-inhibited L929 cells

1971 • 98 citations

Metabolic Basis for the Actions of Analogs of Purines and Pyrimidines

1965 • 96 citations

Lymphocyte Transformation in Megaloblastic Anaemia: Morphology and DNA Synthesis

1970 • 92 citations

The deoxyribonucleoside 5′-triphosphate (dATP and dTTP) pool in phytohemagglutinin-stimulated and non-stimulated human lymphocytes

1973 • 90 citations

Changes in the deoxyribonucleoside triphosphate pools of mouse 5178Y lymphoma cells following exposure to methotrexate or 5-fluorouracil.

1973 • 88 citations

Nature of DNA Precursors

1971 • 85 citations

Factors determining cell sensitivity to methotrexate: Studies of folate and deoxyribonucleoside triphosphate pools in five mammalian cell lines

1974 • 84 citations

Deoxyribonucleoside 5′-triphosphate pool fluctuations during the mamalian cell cycle

1972 • 79 citations

Purineless death as a link between growth rate and cytotoxicity by methotrexate.

1972 • 77 citations

Turnover of the Deoxyribonucleoside Triphosphates in Escherichia coli 15 T during Thymine Starvation

1971 • 67 citations

Toxicity of Trimethoprim-Sulphamethoxazole in Patients with Megaloblastic Haemopoiesis

1972 • 63 citations

Mechanism of Pyrimethamine-Induced Megaloblastosis in Human Bone Marrow

1969 • 62 citations

Studies on the acid-soluble nucleotide pool in Escherichia coli

1967 • 56 citations

Specific Increase in Pyrimidine Deoxynucleoside Transport at the Time of Deoxyribonucleic Acid Synthesis in 3T3 Mouse Cells

1973 • 43 citations

Deoxyribonucleotide Pools during Liver Regeneration

1973 • 40 citations

Methylation of uracil deoxyriboside by soluble enzymes of thymus

1957 • 39 citations

Transport of Methotrexate into Normal Haemopoietic Cells and into Leukaemic Cells and its Effects on DNA Synthesis

1973 • 39 citations

Unbalanced Deoxyribonucleotide Synthesis Caused by Methotrexate

1972 • 36 citations

Effect of trimethoprim on folate-dependent DNA synthesis in human bone marrow

1972 • 31 citations

Uptake of Vitamin B₁₂ by Phytohaemagglutinin‐Transformed Lymphocytes

1973 • 29 citations

Absence of an effect of amethopterin and 5-fluorodeoxyuridine upon levels of thymidine triphosphate in HeLa cells.

1971 • 28 citations

On the mechanism of thymineless death in Bacillus subtilis.

1967 • 28 citations

Deoxyribonucleoside Triphosphate Pools of Normal and Transformed Baby-Hamster-Kidney Cells

1972 • 24 citations

Selective metabolic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea upon de novo purine biosynthesis.

1971 • 13 citations

Abstracts of Lectures on the Geographical Distribution of Diseases in England and Wales

1871 • 3 citations

Effect of Drugs which Cause Megaloblastosis on the Free Intracellular Pools of Dna Precursors

1973 • 2 citations