Regulation of lipid metabolism by cytokines during host defense

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Lipids, lipoproteins, triglyceride clearance, and cytokines in human immunodeficiency virus infection and the acquired immunodeficiency syndrome.

1992 • 784 citations

Hypertriglyceridemia in the acquired immunodeficiency syndrome

1989 • 446 citations

Tumor necrosis factor-alpha stimulates hepatic lipogenesis in the rat in vivo.

1987 • 400 citations

Endotoxin rapidly induces changes in lipid metabolism that produce hypertriglyceridemia: low doses stimulate hepatic triglyceride production while high doses inhibit clearance.

1992 • 344 citations

Effects of endotoxin and cytokines on lipid metabolism

1994 • 308 citations

Interleukin-6 stimulates hepatic triglyceride secretion in rats.

1995 • 287 citations

Resting energy expenditure, caloric intake, and short-term weight change in human immunodeficiency virus infection and the acquired immunodeficiency syndrome

1992 • 283 citations

Interferons and tumor necrosis factors have similar catabolic effects on 3T3 L1 cells.

1986 • 280 citations

Increased de novo hepatic lipogenesis in human immunodeficiency virus infection.

1993 • 225 citations

Role for circulating lipoproteins in protection from endotoxin toxicity

1995 • 215 citations

Multiple Cytokines Stimulate Hepatic Lipid Synthesisin Vivo*

1989 • 209 citations

Tumor necrosis factor mediates the effects of endotoxin on cholesterol and triglyceride metabolism in mice.

1993 • 181 citations

Lysis of Trypanosoma brucei by a Toxic Subspecies of Human High Density Lipoprotein

1989 • 176 citations

Cytokines induce catabolic effects in cultured adipocytes by multiple mechanisms

1994 • 137 citations

Triglyceride-rich lipoproteins prevent septic death in rats.

1995 • 109 citations

Tumor necrosis factor: immunologic, antitumor, metabolic, and cardiovascular activities.

1990 • 104 citations

Effect of interleukin-1 on lipid metabolism in the rat. Similarities to and differences from tumor necrosis factor.

1991 • 91 citations

Recombinant gamma interferon induces hypertriglyceridemia and inhibits post-heparin lipase activity in cancer patients.

1986 • 78 citations

Persistence of the hypertriglyceridemic effect of tumor necrosis factor despite development of tachyphylaxis to its anorectic/cachectic effects in rats.

1989 • 71 citations

Leukemia inhibitory factor induces changes in lipid metabolism in cultured adipocytes.

1994 • 65 citations

Diet affects the mechanisms by which TNF stimulates hepatic triglyceride production

1990 • 62 citations

Tumor necrosis factor, cytokines, and the hyperlipidemia of infection

1991 • 48 citations

Wasting in the Acquired Immunodeficiency Syndrome

1992 • 44 citations