Activation of NF‐κB in human neutrophils during phagocytosis of bacteria independently of oxidant generation

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

1991 • 3,819 citations

The Glomerular Permeability Determined by Dextran Clearance Using Sephadex Gel Filtration

1968 • 2,659 citations

Inflammation. Basic principles and clinical correlates

1989 • 2,424 citations

Structure, Regulation and Function of NF-kappaB

1994 • 2,110 citations

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

1995 • 1,739 citations

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.

1993 • 1,330 citations

IMF-κB and Rel: Participants in a Multiform Transcriptional Regulatory System

1993 • 967 citations

Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus.

1990 • 960 citations

The production of cytokines by polymorphonuclear neutrophils

1995 • 918 citations

Redox Regulation of NF-kappa B Activation

1997 • 852 citations

A Novel Role for the β2 Integrin CD11b/CD18 in Neutrophil Apoptosis: A Homeostatic Mechanism in Inflammation

1996 • 645 citations

The involvement of NF-κB in β-interferon gene regulation reveals its role as widely inducible mediator of signal transduction

1989 • 494 citations

Nuclear factor kappa B, a mediator of lipopolysaccharide effects

1993 • 476 citations

Poly's lament: the neglected role of the polymorphonuclear neutrophil in the afferent limb of the immune response

1992 • 459 citations

Phagocytosing neutrophils produce and release high amounts of the neutrophil-activating peptide 1/interleukin 8.

1991 • 442 citations

Separation of oxidant-initiated and redox-regulated steps in the NF-kappa B signal transduction pathway.

1994 • 389 citations

DNA binding of purified transcription factor NF-kappa B. Affinity, specificity, Zn2+ dependence, and differential half-site recognition.

1991 • 349 citations

Activation of the NF-κB Pathway by Inflammatory Stimuli in Human Neutrophils

1997 • 321 citations

Neutrophils undergo apoptosis following ingestion of Escherichia coli.

1996 • 303 citations

Study of Gene Regulation by NF-κB and AP-1 in Response to Reactive Oxygen Intermediates

1997 • 284 citations

Reactive oxygen intermediates activate NF-kappa B in a tyrosine kinase- dependent mechanism and in combination with vanadate activate the p56lck and p59fyn tyrosine kinases in human lymphocytes

1993 • 260 citations

Redox status of cells influences constitutive or induced NF-kappa B translocation and HIV long terminal repeat activity in human T and monocytic cell lines.

1992 • 242 citations

Expression of interleukin-1 alpha and beta genes by human blood polymorphonuclear leukocytes.

1991 • 156 citations

Activation of NFκB by the respiratory burst of macrophages

1996 • 123 citations

A family of serine proteases expressed exclusively in myelo-monocytic cells specifically processes the nuclear factor-kappa B subunit p65 in vitro and may impair human immunodeficiency virus replication in these cells.

1994 • 102 citations

Purification of alpha1-Antitrypsin from Plasma through Thiol-Disulfide Interchange

1975 • 96 citations

Cytokine regulation of IL-1 beta gene expression in the human polymorphonuclear leukocyte.

1990 • 91 citations

Phagocytosis of Opsonized Yeast Induces Tumor Necrosis Factor-α mRNA Accumulation and Protein Release by Human Polymorphonuclear Leukocytes

1991 • 83 citations

Endotoxin-induced cytokine gene expression in vivo. IV. Expression of interleukin-1 alpha/beta and interleukin-1 receptor antagonist mRNA during endotoxemia and during endotoxin-initiated local acute inflammation.

1992 • 81 citations

Rickettsia rickettsii infection of cultured human endothelial cells induces NF-kappaB activation

1997 • 71 citations

Expression of interleukin‐1 receptor antagonist (IL‐1ra) by human circulating polymorphonuclear cells

1993 • 69 citations

Modification of neutrophil oxidant production with diphenyleneiodonium and its effect on bacterial killing

1995 • 66 citations

Cell Type- and Developmental Stage-specific Activation of NF-κB by fMet-Leu-Phe in Myeloid Cells

1997 • 65 citations

Anti-Ehrlichia chaffeensis antibody complexed with E. chaffeensis induces potent proinflammatory cytokine mRNA expression in human monocytes through sustained reduction of IkappaB-alpha and activation of NF-kappaB

1997 • 63 citations

Activation of transcription factor NF‐κB by phagocytic stimuli in human neutrophils

1997 • 48 citations

The binding of immobilized IgG2a to Fc gamma 2a receptor activates NF-kappa B via reactive oxygen intermediates and tumor necrosis factor-alpha 1.

1994 • 34 citations

NF-κB Transcription Factor Activation by Hydrogen Peroxide Can Be Decreased by 2,3-Dihydroxybenzoic Acid and Its Ethyl Ester Derivative

1995 • 22 citations

Characteristics of aggregated immunoglobulin G as an immunologic phagocytic stimulus for granule enzyme release from human neutrophils

1986 • 5 citations