Mapping functional domains in the promoter region of the herpes thymidine kinase gene.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Regulation of Herpesvirus Macromolecular Synthesis I. Cascade Regulation of the Synthesis of Three Groups of Viral Proteins

1974 • 1,479 citations

Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells

1977 • 1,411 citations

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

1979 • 1,339 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

Control of herpes simplex virus type 1 mRNA synthesis in cells infected with wild-type virus or the temperature-sensitive mutant tsK

1979 • 496 citations

Genetic and physical linkage of exogenous sequences in transformed cells

1980 • 486 citations

Fine-structure mapping and functional analysis of temperature-sensitive mutants in the gene encoding the herpes simplex virus type 1 immediate early protein VP175

1980 • 436 citations

A herpes simplex virus type 1 function continuously required for early and late virus RNA synthesis

1980 • 429 citations

Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1.

1981 • 388 citations

Transforming DNA integrates into the host chromosome

1981 • 311 citations

Transfer of the gene for thymidine kinase to thymidine kinase-deficient human cells by purified herpes simplex viral DNA.

1977 • 246 citations

Cloning of the active thymidine kinase gene of herpes simplex virus type 1 in Escherichia coli K-12.

1979 • 238 citations

In vitro mutagenesis of a circular DNA molecule by using synthetic restriction sites.

1978 • 200 citations

Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of herpes simplex type 1 virus

1979 • 189 citations

Biochemical transformation of mouse cells by fragments of herpes simplex virus DNA

1977 • 180 citations

Expression of the herpes thymidine kinase gene in Xenopus laevis oocytes: an assay for the study of deletion mutants constructed in vitro

1980 • 152 citations

Hybrid plasmids containing an active thymidine kinase gene of Herpes simplex virus 1

1979 • 147 citations

Acquisition of thymidine kinase activity by herpes simplex infected mouse fibroblast cells

1963 • 146 citations

Herpes simplex virus gene expression in transformed cells. I. Regulation of the viral thymidine kinase gene in transformed L cells by products of superinfecting virus

1976 • 94 citations

Viral-associated and induced enzymes

1979 • 63 citations

Expression of the Viral Thymidine Kinase Gene in Herpes Simplex Virus-Transformed L Cells

1974 • 60 citations

Regulation of herpesvirus thymidine kinase activity in LM(TK−) cells transformed by ultraviolet light-irradiated herpes simplex virus

1977 • 52 citations

Thymidine kinase activity of biochemically transformed mouse cells after superinfection by thymidine kinase-negative, temperature-sensitive, herpes simplex virus mutants

1978 • 40 citations

Herpes simplex virus thymidine kinase transcripts are absent from both nucleus and cytoplasm during infection in the presence of cycloheximide

1980 • 29 citations

Linkage and Expression of Foreign DNA in Cultured Animal Cells

1981 • 29 citations

Biochemical transformation of thymidine kinase (TK)-deficient mouse cells by herpes simplex virus type 1 DNA fragments purified from hybrid plasmids

1980 • 26 citations