Biochemical transformation of thymidine kinase (TK)-deficient mouse cells by herpes simplex virus type 1 DNA fragments purified from hybrid plasmids

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

A membrane-filter technique for the detection of complementary DNA

1966 • 3,996 citations

Calcium-dependent bacteriophage DNA infection

1970 • 2,743 citations

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1979 • 1,830 citations

Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells

1977 • 1,411 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

Deletion of thymidine kinase activity from L cells resistant to bromodeoxyuridine

1963 • 611 citations

The structure and isomerization of herpes simplex virus genomes

1979 • 331 citations

Equilibrium sedimentation in density gradients of DNA preparations from animal tissues

1961 • 289 citations

Transfer of the gene for thymidine kinase to thymidine kinase-deficient human cells by purified herpes simplex viral DNA.

1977 • 246 citations

Cloning of the active thymidine kinase gene of herpes simplex virus type 1 in Escherichia coli K-12.

1979 • 238 citations

Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of herpes simplex type 1 virus

1979 • 189 citations

Hybrid plasmids containing an active thymidine kinase gene of Herpes simplex virus 1

1979 • 147 citations

Acquisition of thymidine kinase activity by herpes simplex infected mouse fibroblast cells

1963 • 146 citations

Herpes simplex virus DNA isolation from infected cells with a novel procedure

1979 • 90 citations

Distinctive properties of thymidine kinase isozymes induced by human and avian herpesviruses

1974 • 71 citations

Mechanism of regulation of deoxythymidine kinase of Escherichia coli

1967 • 65 citations

Viral-associated and induced enzymes

1979 • 63 citations

Construction and characterization of E. coli promoter-probe plasmid vectors I. Cloning of promoter-containing DNA fragments

1979 • 62 citations

Regulation of herpesvirus thymidine kinase activity in LM(TK−) cells transformed by ultraviolet light-irradiated herpes simplex virus

1977 • 52 citations

Genetic and physical evidence for the polarity of transcription of the thymidine kinase gene of herpes simplex virus

1980 • 49 citations

Construction, propagation and expression of simian virus 40 recombinant genomes containing the Escherichia coli gene for thymidine kinase and a Saccharomyces cerevisae gene for tyrosine transfer RNA

1979 • 34 citations

Subcellular distribution of simian virus 40 T antigen species in various cell lines: The 56K protein

1980 • 31 citations

Initiation of protein synthesis in bacteria at a translational start codon of mamalian cDNA: effects of the preceding nucleotide sequence.

1980 • 30 citations

Purification of vaccinia virus-induced thymidine kinase activity from [35S]methionine-labeled cells

1977 • 27 citations

Detection of Herpes Simplex Virus Thymidine Kinase Polypeptides in Cells Labeled with <sup>35</sup>S-Methionine

1978 • 23 citations

Herpesvirus-associated nuclear antigen(s) in cells biochemically transformed by fragments of herpesvirus DNA and in somatic cell hybrids

1980 • 10 citations