Healthy and pathological processes in adult development: new evidence from neuroimaging of the aging brain

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound‐B

2004 • 4,223 citations

Insights into the ageing mind: a view from cognitive neuroscience

2004 • 2,112 citations

Molecular, Structural, and Functional Characterization of Alzheimer's Disease: Evidence for a Relationship between Default Activity, Amyloid, and Memory

2005 • 1,993 citations

An application of prefrontal cortex function theory to cognitive aging.

1996 • 1,933 citations

Memory and Executive Function in Aging and AD

2004 • 1,435 citations

A unified approach for morphometric and functional data analysis in young, old, and demented adults using automated atlas-based head size normalization: reliability and validation against manual measurement of total intracranial volume

2004 • 1,212 citations

Dynamics of Gray Matter Loss in Alzheimer's Disease

2003 • 1,088 citations

Mild Cognitive Impairment Can Be Distinguished From Alzheimer Disease and Normal Aging for Clinical Trials

2004 • 949 citations

Comparison of different MRI brain atrophy rate measures with clinical disease progression in AD

2004 • 791 citations

Task-independent and Task-specific Age Effects on Brain Activity during Working Memory, Visual Attention and Episodic Retrieval

2004 • 774 citations

Differential Vulnerability of Anterior White Matter in Nondemented Aging with Minimal Acceleration in Dementia of the Alzheimer Type: Evidence from Diffusion Tensor Imaging

2004 • 650 citations

Neuroimaging studies of shifting attention: a meta-analysis

2004 • 633 citations

Hippocampus and entorhinal cortex in mild cognitive impairment and early AD

2003 • 617 citations

Mapping hippocampal and ventricular change in Alzheimer disease

2004 • 600 citations

Global and local gray matter loss in mild cognitive impairment and Alzheimer's disease

2004 • 585 citations

Relationship between hippocampal volume and memory ability in healthy individuals across the lifespan: review and meta-analysis

2004 • 584 citations

Medial temporal lobe function and structure in mild cognitive impairment

2004 • 520 citations

Brain aging: reorganizing discoveries about the aging mind

2005 • 515 citations

Aging and the Neural Correlates of Successful Picture Encoding: Frontal Activations Compensate for Decreased Medial-Temporal Activity

2005 • 462 citations

Focal Decline of Cortical Thickness in Alzheimer's Disease Identified by Computational Neuroanatomy

2004 • 427 citations

Differential aging of the medial temporal lobe

2004 • 415 citations

Diffusion tensor imaging of adult age differences in cerebral white matter: relation to response time

2004 • 370 citations

Frontal circuitry degradation marks healthy adult aging: Evidence from diffusion tensor imaging

2005 • 350 citations

MRI-derived entorhinal volume is a good predictor of conversion from MCI to AD

2004 • 325 citations

In-Vivo Imaging of Alzheimer Disease -Amyloid With [11C]SB-13 PET

2004 • 321 citations

Ultrastructural Hippocampal and White Matter Alterations in Mild Cognitive Impairment: A Diffusion Tensor Imaging Study

2004 • 305 citations

Shrinkage of the Entorhinal Cortex over Five Years Predicts Memory Performance in Healthy Adults

2004 • 270 citations

Color-coded diffusion-tensor-imaging of posterior cingulate fiber tracts in mild cognitive impairment

2005 • 265 citations

The neurobiology of memory changes in normal aging

2003 • 260 citations

Memory encoding in Alzheimer's disease: an fMRI study of explicit and implicit memory

2005 • 256 citations

The role of the striatal dopamine transporter in cognitive aging

2005 • 247 citations

Memory and executive function in older adults: relationships with temporal and prefrontal gray matter volumes and white matter hyperintensities

2004 • 207 citations

Verbal episodic memory impairment in Alzheimer's disease: a combined structural and functional MRI study

2004 • 197 citations

MRI predictors of risk of incident Alzheimer disease

2005 • 184 citations

Preserved Neural Correlates of Priming in Old Age and Dementia

2004 • 169 citations

Frontal-Hippocampal Double Dissociation Between Normal Aging and Alzheimer's Disease

2004 • 158 citations

Selection requirements during verb generation: differential recruitment in older and younger adults

2004 • 149 citations

Dissociating Age-related Changes in Cognitive Strategy and Neural Efficiency Using Event- related fMRI

2005 • 118 citations

An Age-Related Deficit in Prefrontal Cortical Function Associated With Refreshing Information

2004 • 114 citations

Preservation of hippocampal volume throughout adulthood in healthy men and women

2004 • 105 citations

Hippocampal adaptation to face repetition in healthy elderly and mild cognitive impairment

2004 • 101 citations

Age-related Changes in Neural Activity during Visual Target Detection Measured by fMRI

2003 • 98 citations

Deep processing activates the medial temporal lobe in young but not in old adults

2003 • 98 citations

The functional anatomy of divided attention in amnestic mild cognitive impairment

2005 • 96 citations

Prefrontal cortex and the mediation of proactive interference in working memory

2004 • 84 citations

Event-related functional magnetic resonance imaging investigation of executive control in very old individuals with mild cognitive impairment

2005 • 75 citations

PET Studies of Net Blood—Brain Clearance of FDOPA to Human Brain: Age-Dependent Decline of [¹⁸F]Fluorodopamine Storage Capacity

2005 • 54 citations

Automated brain tissue assessment in the elderly and demented population: Construction and validation of a sub-volume probabilistic brain atlas

2005 • 53 citations

Age differences in orbitofrontal activation: an fMRI investigation of delayed match and nonmatch to sample

2004 • 51 citations

fMRI differences in encoding and retrieval of pictures due to encoding strategy in the elderly

2003 • 50 citations

Correlation between different memory systems and striatal dopamine D₂/D₃ receptor density: a single photon emission computed tomography study

2005 • 46 citations

Comparability of functional MRI response in young and old during inhibition

2003 • 43 citations

Mental calculation impairment in Alzheimer's disease: a functional magnetic resonance imaging study

2004 • 34 citations

Relating Medial Temporal Lobe Volume to Frontal fMRI Activation for Memory Encoding in Older Adults

2005 • 32 citations

Regional cerebral blood flow deficits in mild Alzheimer's disease using high resolution single photon emission computerized tomography

2005 • 24 citations