In-Vivo Imaging of Alzheimer Disease -Amyloid With [11C]SB-13 PET

A new look at the statistical model identification

1974 • 46,507 citations

Clinical diagnosis of Alzheimer's disease

1984 • 27,279 citations

Neuropathological stageing of Alzheimer-related changes

1991 • 14,533 citations

The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

2002 • 13,092 citations

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound‐B

2004 • 4,223 citations

Phases of Aβ-deposition in the human brain and its relevance for the development of AD

2002 • 2,850 citations

Population-Based Norms for the Mini-Mental State Examination by Age and Educational Level

1993 • 2,707 citations

Simplified Reference Tissue Model for PET Receptor Studies

1996 • 1,980 citations

The Topographical and Neuroanatomical Distribution of Neurofibrillary Tangles and Neuritic Plaques in the Cerebral Cortex of Patients with Alzheimer's Disease

1991 • 1,344 citations

Parametric Imaging of Ligand-Receptor Binding in PET Using a Simplified Reference Region Model

1997 • 1,064 citations

Targeting small Aβ oligomers: the solution to an Alzheimer's disease conundrum?

2001 • 975 citations

Localization of Neurofibrillary Tangles and Beta-Amyloid Plaques in the Brains of Living Patients With Alzheimer Disease

2002 • 761 citations

The end of world population growth

2001 • 653 citations

Statistics to tell the truth, the whole truth, and nothing but the truth Formulae, illustrative numerical examples, and heuristic interpretation of effect size analyses for neuropsychological researchers

2001 • 338 citations

Diffuse senile plaques occur commonly in the cerebellum in Alzheimer's disease.

1989 • 336 citations

X-34, A Fluorescent Derivative of Congo Red: A Novel Histochemical Stain for Alzheimer's Disease Pathology

2000 • 270 citations

Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease

2002 • 232 citations

11C-labeled stilbene derivatives as Aβ-aggregate-specific PET imaging agents for Alzheimer’s disease

2003 • 202 citations

Alzheimer's disease: striatal amyloid deposits and neurofibrillary changes.

1990 • 192 citations

A JAVA environment for medical image data analysis: Initial application for brain PET quantitation

1998 • 180 citations

A Strategy for Removing the Bias in the Graphical Analysis Method

2001 • 173 citations

In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer’s brain using the positron emission tomography molecular imaging probe 2-(1-{6-[(2-[18F]fluoroethyl)(methyl)amino]-2-naphthyl}ethylidene)malononitrile

2003 • 170 citations

Alzheimer's disease: amyloid plaques in the cerebellum

1989 • 150 citations

A meta-analysis of structural and functional brain imaging in dementia of the Alzheimer's type: a neuroimaging profile.

2003 • 141 citations

Diffuse type of senile plaques in the cerebellum of Alzheimer-type dementia demonstrated by? protein immunostain

1989 • 139 citations

An introduction to PET and SPECT neuroreceptor quantification models.

2001 • 133 citations

Binding of two potential imaging agents targeting amyloid plaques in postmortem brain tissues of patients with Alzheimer's disease

2004 • 132 citations

Neurofibrillary changes confined to the entorhinal region and an abundance of cortical amyloid in cases of presenile and senile dementia

1990 • 124 citations

Requirements and implementation of a flexible kinetic modeling tool.

1997 • 114 citations

Progression of Regional Neuropathology in Alzheimer Disease and Normal Elderly: Findings from the Nun Study

1999 • 103 citations

A rapid one‐step radiosynthesis of the β‐amyloid imaging radiotracer N‐methyl‐[¹¹C]2‐(4′‐methylaminophenyl)‐6‐hydroxybenzothiazole ([¹¹C]‐6‐OH‐BTA‐1)

2004 • 100 citations

Health care utilization and costs of Alzheimer's disease: the role of co-morbid conditions, disease stage, and pharmacotherapy.

2002 • 90 citations

Modified Bielschowsky stain and immunohistochemical studies on striatal plaques in Alzheimer's disease

1990 • 78 citations

Modified Bielschowsky and Immunocytochemical Studies on Cerebellar Plaques in Alzheimer's Disease

1990 • 72 citations

Quantitative Evidence for Neuroanatomic and Neuropsychological Markers in Dementia of the Alzheimer's Type

1998 • 68 citations

The distribution of amyloid beta protein deposition in the corpus striatum of patients with Alzheimer's disease.

1997 • 54 citations

In Vivo Brain Imaging of Tangle Burden in Humans

2002 • 51 citations

Neuroimaging of Vessel Amyloid in Alzheimer's Disease^a,b

1997 • 39 citations

Potential for imaging cerebral amyloid deposits using 123I-labelled serum amyloid P component and SPET

1996 • 17 citations

O3-03-05 Human amyloid-imaging studies in controls, mild cognitive impairment and Alzheimer's disease using Pittsburg compound-B

2004 • 8 citations

O3-03-06 Plaque and tangle brain imaging using [F-18]FDDNP-PET differentiates Alzheimer's disease, mild cognitive impairment, and older controls

2004 • 5 citations

O3-03-02 Binding of two potential imaging agents targeting amyloid plaques in Alzheimer's disease brains

2004 • 3 citations