Curcumin inhibits telomerase activity through human telomerase reverse transcritpase in MCF-7 breast cancer cell line

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1994 • 7,043 citations

Telomeres shorten during ageing of human fibroblasts

1990 • 5,530 citations

A survey of telomerase activity in human cancer

1997 • 2,747 citations

hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization

1997 • 1,786 citations

Telomere reduction in human colorectal carcinoma and with ageing

1990 • 1,672 citations

Activation of Transcription Factor NF-κB Is Suppressed by Curcumin (Diferuloylmethane)

1995 • 1,352 citations

Myc activates telomerase

1998 • 650 citations

Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

1998 • 614 citations

Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer.

1999 • 595 citations

Curcumin, an Anti-tumor Promoter and Anti-inflammatory Agent, Inhibits Induction of Nitric Oxide Synthase in Activated Macrophages

1995 • 477 citations

Human telomerase contains evolutionarily conserved catalytic and structural subunits

1997 • 476 citations

Curcuminoids as Potent Inhibitors of Lipid Peroxidation

1994 • 472 citations

Telomerase activity, cell proliferation, and cancer

1998 • 402 citations

Role of capsaicin, curcumin and dietary n — 3 fatty acids in lowering the generation of reactive oxygen species in rat peritoneal macrophages

1994 • 397 citations

Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells.

1991 • 381 citations

Reconstitution of human telomerase activity in vitro

1998 • 347 citations

Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer.

1998 • 301 citations

Myc target genes

1997 • 289 citations

Differentiation of immortal cells inhibits telomerase activity.

1995 • 269 citations

Inhibitory effects of curcumin on protein kinase C activity induced by 12-O-tetradecanoyl-phorbol-13-acetate in NIH 3T3 cells

1993 • 252 citations

Three inhibitors of type 1 human immunodeficiency virus long terminal repeat-directed gene expression and virus replication.

1993 • 225 citations

Diminution of singlet oxygen-induced DNA damage by curcmin and related antioxidants

1994 • 188 citations

Clinical implications of telomerase in cancer

1997 • 186 citations

Human Telomerase Inhibition by Regioisomeric Disubstituted Amidoanthracene-9,10-diones

1998 • 157 citations

1,4- and 2,6-Disubstituted Amidoanthracene-9,10-dione Derivatives as Inhibitors of Human Telomerase

1998 • 155 citations

Inhibitory effect of curcumin on epidermal growth factor receptor kinase activity in A431 cells

1994 • 153 citations

Differential sensitivity of human mammary epithelial and breast carcinoma cell lines to curcumin

1999 • 146 citations

Inhibition of Telomerase Activity by PKC Inhibitors in Human Nasopharyngeal Cancer Cells in Culture

1997 • 138 citations

Selective inhibition of telomerase activity during terminal differentiation of immortal cell lines.

1996 • 127 citations

Inhibition of Tissue Factor Gene Activation in Cultured Endothelial Cells by Curcumin

1997 • 127 citations

Inhibitory effects of curcumin and capsaicin on phorbol ester‐induced activation of eukaryotic transcription factors, NF‐κB and AP‐1

2000 • 126 citations

Effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate- and ultraviolet B light-induced expression of c-Jun and c-Fos in JB6 cells and in mouse epidermis

1994 • 115 citations

Curcumin inhibits TPA induced expression of c-fos, c-jun and c-myc proto-oncogenes messenger RNAs in mouse skin

1994 • 114 citations

Telomerase activation: one step on the road to cancer?

1999 • 95 citations

Telomeres, Telomerase, and Cancer

2000 • 78 citations

Effects of N-(4-Hydroxyphenyl)retinamide on hTERT Expression in the Bronchial Epithelium of Cigarette Smokers

2001 • 58 citations

Telomerase Activity in Human Leukemic Cell Lines Is Inhibited by Antisense Pentadecadeoxynucleotides Targeted against c-myc mRNA

1997 • 55 citations

Down-Regulation of Telomerase Activity in Malignant Lymphomas by Radiation and Chemotherapeutic Agents

2001 • 51 citations

New quinolones, ofloxacin and levofloxacin, inhibit telomerase activity in transitional cell carcinoma cell lines

1997 • 46 citations

Telomerase activity and expression of hTRT and hTR in gastrointestinal stromal tumors in comparison with extragastrointestinal sarcomas.

2000 • 34 citations

Complex Regulation of Telomerase Activity

2001 • 21 citations

Bcl-2 and mdr-1 gene expression during doxorubicin-induced apoptosis in murine leukemic P388 and P388/R84 cells.

1997 • 17 citations