Urinary trypsin inhibitor (UTI) and fragments derived from UTI by limited proteolysis efficiently inhibit tumor cell invasion

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

A rapid in vitro assay for quantitating the invasive potential of tumor cells.

1987 • 1,787 citations

Metastatic potential correlates with enzymatic degradation of basement membrane collagen

1980 • 1,778 citations

The use of avidin-biotin interaction in immunoenzymatic techniques.

1979 • 1,734 citations

Basement membrane complexes with biological activity

1986 • 1,489 citations

Tumor invasion and the extracellular matrix.

1983 • 960 citations

Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade

1986 • 764 citations

[46] Fibronectin: Purification, immunochemical properties, and biological activities

1982 • 542 citations

Autocrine saturation of pro-urokinase receptors on human A431 cells

1986 • 361 citations

Effects of inhibitors of plasminogen activator, serine proteinases, and collagenase IV on the invasion of basement membranes by metastatic cells

1988 • 352 citations

Cathepsin B efficiently activates the soluble and the tumor cell receptor-bound form of the proenzyme urokinase-type plasminogen activator (Pro-uPA).

1991 • 347 citations

Degradation of basement membrane type IV collagen and lung subendothelial matrix by rat mammary adenocarcinoma cell clones of differing metastatic potentials.

1987 • 315 citations

Inhibition of receptor-bound urokinase by plasminogen-activator inhibitors.

1990 • 272 citations

Characterization of the Cellular Binding Site for the Urokinase-type Plasminogen Activator

1989 • 248 citations

Modulation of metastatic potential by cell surface urokinase of murine melanoma cells.

1988 • 223 citations

Basement Membrane and the Invasive Activity of Metastatic Tumor Cells

1986 • 209 citations

Inhibition of in vitro ovarian cancer cell invasion by modulation of urokinase-type plasminogen activator and cathepsin B.

1992 • 168 citations

Effect of Natural Protease Inhibitors and a Chemoattractant on Tumor Cell Invasion In Vitro

1982 • 141 citations

Inhibition of cancer cell urokinase plasminogen activator by its specific inhibitor PAI-2 and subsequent effects on extracellular matrix degradation.

1990 • 112 citations

Mouse L cells expressing human prourokinase-type plasminogen activator: effects on extracellular matrix degradation and invasion.

1989 • 99 citations

Kunitz-Type Proteinase Inhibitors Derived by Limited Proteolysis of the Inter-α-Trypsin Inhibitor, IV. The Amino Acid Sequence of the Human Urinary Trypsin Inhibitor Isolated by Affinity Chromatography

1981 • 88 citations

Invasion of reconstituted basement membrane matrix is not correlated to the malignant metastatic cell phenotype.

1991 • 87 citations

Kunitz-Type Proteinase Inhibitors Derived by Limited Proteolysis of the Inter-α-Trypsin Inhibitor, V^[1–4]. Attachments of Carbohydrates in the Human Urinary Trypsin Inhibitor Isolated by Affinity Chromatography

1981 • 72 citations

Identification and characterization of the murine cell surface receptor for the urokinase‐type plasminogen activator

1992 • 62 citations

Cell membrane receptors for urokinase plasminogen activator are increased in malignant ovarian tumours

1991 • 59 citations

Receptor for Plasmin on Human Carcinoma Cells1

1988 • 55 citations

Stracture of inter-α-inhibitor (inter-α-trypsin inhibitor) and pre-α-inhibitor: current state and proposition of a new terminology

1990 • 51 citations

Human Inter-α-Trypsin Inhibitor: Localization of the Kunitz-Type Domains in the N-terminal Part of the Molecule and their Release by a Trypsin-Like Proteinase

1985 • 46 citations

A Proteoglycan Related to the Urinary Trypsin Inhibitor (UTI) Links the two Heavy Chains of Inter-α-Trypsin Inhibitor

1989 • 46 citations

Radioimmunological Quantitation of the Urinary Trypsin Inhibitor in Normal Blood and Urine

1989 • 41 citations

Structure of inter-alpha-inhibitor (inter-alpha-trypsin inhibitor) and pre-alpha-inhibitor: current state and proposition of a new terminology.

1990 • 36 citations

Elastase released from human granulocytes stimulated with N‐formyl‐chemotactic peptide prevents activation of tumor cell prourokinase (pro‐uPA)

1989 • 30 citations

Membrane invasion culture system (MICS).

1984 • 28 citations

Elastase Inhibition by the Inter-α-Trypsin Inhibitor and Derived Inhibitors of Man and Cattle

1983 • 25 citations

Tissue Plasminogen Activator and Urokinase in Normal, Dysplastic and Cancerous Squamous Epithelium of the Uterine Cervix

1987 • 20 citations

Inhibitory Effect of Human Urinary Trypsin Inhibitor (Urinastatin) on Lysosomal Thiol Proteinases

1986 • 17 citations

Plasma proteins immunologically related to inter-α-trypsin inhibitor

1988 • 16 citations

Kunitz-Type Proteinase Inhibitors Derived by Limited Proteolysis of the Inter-α-Trypsin Inhibitor, VIII. Characterization of the Bovine Inhibitor as Double-Headed Tiypsin-Elastase Inhibitor

1983 • 14 citations

Differential Detection of Single-Chain and Two-Chain Urokinase-Type Plasminogen Activator by a New Immunoadsorbent-Amidolytic Assay (IAA)

1986 • 12 citations

[Establishment and characterization of human ovarian endometrioid carcinoma cell line].

1989 • 10 citations

[Cytotoxicity of T-lymphocytes from a patient with choriocarcinoma to autologous tumor cultured cells--stimulation with the husband's lymphocytes].

1987 • 2 citations