Selective neurotoxicity of COOH-terminal fragments of the β-amyloid precursor protein

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1987 • 4,544 citations

Cleavage of Amyloid β Peptide During Constitutive Processing of Its Precursor

1990 • 1,388 citations

Neurotoxicity of a Fragment of the Amyloid Precursor Associated with Alzheimer's Disease

1989 • 904 citations

Evidence that β-Amyloid Protein in Alzheimer's Disease Is Not Derived by Normal Processing

1990 • 895 citations

Alzheimer's Disease

1986 • 772 citations

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

1992 • 737 citations

Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

1992 • 432 citations

The Seminal Role of β-Amyloid in the Pathogenesis of Alzheimer Disease

1992 • 182 citations

Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursor

1992 • 175 citations

Kunitz Protease Inhibitor-Containing Amyloid β Protein Precursor Immunoreactivity in Alzheimer's Disease

1992 • 137 citations

Framing β–amyloid

1992 • 130 citations

Overexpression of amyloid precursor protein alters its normal processing and is associated with neurotoxicity

1992 • 81 citations

Increased Expression of β‐Amyloid Protein Precursor and Microtubule‐Associated Protein τ During the Differentiation of Murine Embryonal Carcinoma Cells

1992 • 42 citations

Expression of a carboxy-terminal region of the β-amyloid precursor protein in a heterogeneous culture of neuroblastoma cells: evidence for altered processing and selective neurotoxicity

1992 • 39 citations

Mutation of Glu693 to Gln or Val717 to Ile has no effect on the processing of Alzheimer amyloid precursor protein expressed in COS-1 cells by cDNA transfection

1991 • 24 citations