Alzheimer's Disease

“Mini-mental state”

1975 • 82,784 citations

Clinical diagnosis of Alzheimer's disease

1984 • 27,279 citations

The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects

1968 • 4,041 citations

Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain

1982 • 3,563 citations

Alzheimer's Disease: Cell-Specific Pathology Isolates the Hippocampal Formation

1984 • 2,199 citations

Observations on the brains of demented old people

1970 • 2,066 citations

Validation of a short Orientation-Memory-Concentration Test of cognitive impairment

1983 • 2,050 citations

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

1978 • 2,036 citations

Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

1984 • 1,633 citations

Human Memory and the Cholinergic System

1974 • 1,378 citations

Alzheimer's Disease: X-Ray Spectrometric Evidence of Aluminum Accumulation in Neurofibrillary Tangle-Bearing Neurons

1980 • 995 citations

Paired Helical Filaments in Electron Microscopy of Alzheimer's Disease

1963 • 956 citations

HTLV-III Infection in Brains of Children and Adults with AIDS Encephalopathy

1985 • 899 citations

Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementa

1980 • 866 citations

Some morphometric aspects of the brain in senile dementia of the alzheimer type

1981 • 803 citations

The Natural History of Mental Disorder in Old Age

1955 • 713 citations

A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and alzheimer disease

1981 • 698 citations

Loss of M2 Muscarine Receptors in the Cerebral Cortex in Alzheimer's Disease and Experimental Cholinergic Denervation

1985 • 697 citations

REGIONAL CEREBRAL OXYGEN SUPPLY AND UTILIZATION IN DEMENTIA: A CLINICAL AND PHYSIOLOGICAL STUDY WITH OXYGEN-15 AND POSITRON TOMOGRAPHY A CLINICAL AND PHYSIOLOGICAL STUDY WITH OXYGEN - 15 AND POSITRON TOMOHRAPHY

1981 • 681 citations

Alzheimer's disease: A study of epidemiological aspects

1984 • 529 citations

NEOCORTICAL CHOLINERGIC NEURONS IN ELDERLY PEOPLE

1977 • 490 citations

Cerebral amyloid angiopathy: incidence and complications in the aging brain. II. The distribution of amyloid vascular changes.

1983 • 478 citations

Evidence for a cholinergic projection to neocortex from neurons in basal forebrain.

1979 • 459 citations

Dementia of the Alzheimer Type

1981 • 451 citations

ALUMINOSILICATES AND SENILE PLAQUE FORMATION IN ALZHEIMER'S DISEASE

1986 • 449 citations

Cell loss in the locus coeruleus in senile dementia of Alzheimer type

1981 • 443 citations

Reduced amounts of immunoreactive somatostatin in the temporal cortex in senile dementia of Alzheimer type

1980 • 434 citations

A NEW DEFINITION OF ALZHEIMER'S DISEASE: A HIPPOCAMPAL DEMENTIA

1985 • 422 citations

Alzheimer's Disease: Insolubility of Partially Purified Paired Helical Filaments in Sodium Dodecyl Sulfate and Urea

1982 • 398 citations

Cortical abnormalities in Alzheimer's disease

1984 • 378 citations

Coexistence of cognitive impairment and depression in geriatric outpatients

1982 • 374 citations

Intrahippocampal Septal Grafts Ameliorate Learning Impairments in Aged Rats

1984 • 369 citations

Neurofibrillary tangles of paired helical filaments

1976 • 366 citations

Neurochemical Studies of Early-Onset Alzheimer's Disease

1985 • 356 citations

Nucleus raphe dorsalis in Alzheimer's disease: Neurofibrillary tangles and loss of large neurons

1985 • 332 citations

Regional distribution of muscarinic acetylcholine receptor in normal and Alzheimer's-type dementia brains

1977 • 313 citations

Head injury as a risk factor for Alzheimer's disease

1985 • 300 citations

Distribution of Alzheimer's neurofibrillary changes in the brain stem and hypothalamus of senile dementia

1966 • 299 citations

Diagnostic Accuracy in Presenile Dementia

1979 • 267 citations

Reduced dopamine-beta-hydroxylase activity in Alzheimer's disease

1981 • 266 citations

Somatostatin immunoreactivity in neuritic plaques of Alzheimer's patients

1985 • 263 citations

Reduced Numbers of Somatostatin Receptors in the Cerebral Cortex in Alzheimer's Disease

1985 • 248 citations

THE INVESTIGATION OF DEMENTIA: RESULTS IN 200 CONSECUTIVE ADMISSIONS

1981 • 229 citations

Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex on Guam

1966 • 226 citations

Location of neuronal tangles in somatostatin neurones in Alzheimer's disease

1985 • 214 citations

NEUROFIBRILLARY PATHOLOGY

1970 • 214 citations

Neuropeptides in Alzheimer type dementia

1983 • 214 citations

Choline acetyltransferase activity and histopathology of frontal neocortex from biopsies of demented patients

1982 • 200 citations

Effects of physostigmine and lecithin on memory in Alzheimer disease

1979 • 195 citations

Alzheimer's disease: Anterior-posterior and lateral hemispheric alterations in cortical glucose utilization

1985 • 176 citations

Biopsy‐proved Alzheimer disease presenting as a right parietal lobe syndrome

1982 • 176 citations

Corticotropin-Releasing Factor-like Immunoreactivity in Senile Dementia of the Alzheimer Type

1985 • 161 citations

Norepinephrine and MHPG Levels in CSF and Plasma in Alzheimer's Disease

1984 • 153 citations

GERONTO‐PSYCHIATRIC PERIOD‐PREVALENCE INVESTIGATION IN A GEOGRAPHICALLY DELIMITED POPULATION

1962 • 151 citations

Cortical Substance P‐Like Immunoreactivity in Cases of Alzheimer's Disease and Senile Dementia of the Alzheimer Type

1982 • 141 citations

The clinical utility of the Dementia Rating Scale for assessing Alzheimer patients

1984 • 129 citations

Reduced corticol choline acetyltransferase activity in senile dementia of Alzheimer type is not accompanied by changes in vasoactive intestinal polypeptide

1980 • 128 citations

Volumetric measurements of the cerebrospinal fluid spaces in demented subjects and controls.

1982 • 123 citations

Studies in aging of the brain

1979 • 120 citations

A comparison of changes in the nucleus basalis and locus caeruleus in Alzheimer's disease.

1984 • 117 citations

The Association of Actin with Hirano Bodies

1983 • 112 citations

Reality Orientation and Dementia: A Controlled Trial of Two Approaches

1981 • 110 citations

Familial Alzheimer's disease in two kindreds of the same geographic and ethnic origin

1981 • 103 citations

Alzheimer’s disease

1984 • 102 citations

Elevation of neuropeptide Y (NPY) in substantia innominata in Alzheimer's type dementia

1984 • 101 citations

Does the Incidence of Age Psychosis Decrease?

1981 • 97 citations

Neural transplantation: A review of recent developments and potential applications to the aged brain

1985 • 91 citations

Intralaminar Neurochemical Distributions in Human Midtemporal Cortex: Comparison Between Alzheimer's Disease and the Normal

1984 • 91 citations

Overdiagnosis of Dementia

1981 • 89 citations

Organic Brain Syndrome and Aging

1980 • 87 citations

Somatostatin-like immunoreactivity within neuritic plaques

1985 • 86 citations

Normal cortical concentration of cholecystokinin-like immunoreactivity with reduced choline acetyltransferase activity in senile dementia of Alzheimer type

1981 • 79 citations

Immunological studies in senile dementia of the alzheimer type: Evidence for enhanced suppressor cell activity

1981 • 74 citations

Cholinergic system and constructional praxis: a further study of physostigmine in Alzheimer's disease.

1984 • 73 citations

Twins With Alzheimer's Disease

1981 • 67 citations

Studies in Ageing of the Brain

1972 • 61 citations

Neuropeptide Y-like immunoreactivity in neuritic plaques of Alzheimer's disease

1985 • 58 citations

Physostigmine and its effect on six patients with dementia

1981 • 45 citations

Reminiscence Group Therapy with Psychotic Geriatric Inpatients

1981 • 44 citations

Choline chloride effects on memory in the elderly☆

1980 • 44 citations

Substance P immunoreactivity within neuritic plaques

1985 • 42 citations

Atypical Presentations of Dementia of the Alzheimer Type

1984 • 33 citations

Elevated red blood cell/plasma choline ratio in dimentia of the Alzheimer type: Clinical and polysomnographic correlates

1984 • 25 citations

182 BRAIN TRACE ELEMENT LEVELS IN ALZHEIMERʼS DISEASE BY INSTRUMENTAL NEUTRON ACTIVATION ANALYSIS

1981 • 22 citations

Red blood cell choline. I: Choline in Alzheimer's disease

1985 • 22 citations

Double Blind Study of Lecithin in Patients with Alzheimer's Disease

1981 • 14 citations

Preliminary report

1984 • 7 citations

Commentary on review by Gash et al. potential usefulness and current limitations of neural transplantation in the aged brain

1985 • 1 citations