Elevated levels of members of the STAT family of transcription factors in breast carcinoma nuclear extracts

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

Structural design and molecular evolution of a cytokine receptor superfamily.

1990 • 2,104 citations

Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene

1985 • 1,804 citations

Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

1994 • 1,015 citations

c-erbB-2 Expression and Response to Adjuvant Therapy in Women with Node-Positive Early Breast Cancer

1994 • 981 citations

EPIDERMAL-GROWTH-FACTOR RECEPTOR STATUS AS PREDICTOR OF EARLY RECURRENCE OF AND DEATH FROM BREAST CANCER

1987 • 881 citations

Multiple hormone interactions in the developmental biology of the mammary gland.

1980 • 866 citations

Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

1994 • 813 citations

Pathologic findings from the National Surgical Adjuvant Breast and Bowel Project: prognostic significance of erbB-2 protein overexpression in primary breast cancer.

1990 • 602 citations

The Clinical Significance of Epidermal Growth Factor Receptor (EGF-R) in Human Breast Cancer: A Review on 5232 Patients*

1992 • 585 citations

Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins

1993 • 504 citations

Relationship between c-erbB-2 protein product expression and response to endocrine therapy in advanced breast cancer

1992 • 387 citations

Beta-casein gene promoter activity is regulated by the hormone-mediated relief of transcriptional repression and a mammary-gland-specific nuclear factor.

1991 • 284 citations

Expression of the ERBB3 gene product in breast cancer

1992 • 237 citations

c-erbB-2 oncogene as a prognostic marker in breast cancer

1991 • 137 citations

Interaction of DNA-binding proteins with a milk protein gene promoter in vitro: identification of a mammary gland-specific factor

1991 • 137 citations

Regulation of the sheep beta-lactoglobulin gene by lactogenic hormones is mediated by a transcription factor that binds an interferon-gamma activation site-related element.

1994 • 92 citations

Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response.

1995 • 90 citations

Mammary gland-specific nuclear factor activity is positively regulated by lactogenic hormones and negatively by milk stasis.

1992 • 72 citations

The mammary factor MPBF is a prolactin‐induced transcriptional regulator which binds to STAT factor recognition sites

1994 • 53 citations

β-Casein Gene Promoter Activity Is Regulated by the Hormone- Mediated Relief of Transcriptional Repression and a MammaryGland-Specific Nuclear Factor

1991 • 52 citations

Epidermal growth factor receptor status as a predictor for early recurrence of and death from breast cancer

1988 • 47 citations

Ha-ras and v-raf oncogenes, but not int-2 and c-myc, interfere with the lactogenic hormone dependent activation of the mammary gland specific transcription factor.

1993 • 47 citations

c-erbB-2 Expression and Response to Adjuvant Therapy in Women with Node-Positive Early Breast Cancer

1994 • 41 citations

The proximal milk protein binding factor binding site is required for the prolactin responsiveness of the sheep β-lactoglobulin promoter in Chinese hamster ovary cells

1995 • 24 citations

Growth control of normal and malignant breast epithelium

1989 • 17 citations