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Metabolism of aflatoxin B1, benzo[a]pyrene, and 1,2‐dimethylhydrazine by cultured rat and human colon

Data up to Jan 2025

Published1981
Citations27
References34

Total Citations Per Year

Abstract

References (34)

Polycyclic Hydrocarbons and Cancer

1981 • 737 citations

Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro.

1977 • 507 citations

Identification of the principal aflatoxin B1-DNA adduct formed in vivo in rat liver.

1978 • 246 citations

Nucleoside adducts from the in vitro reaction of benzo[a]pyrene-7,8-dihydrodiol 9,10-oxide or benzo[a]pyrene 4,5-oxide with nucleic acids

1977 • 169 citations

Interindividual Variation in Binding of Benzo[ a ]pyrene to DNA in Cultured Human Bronchi

1976 • 138 citations

Pathogenesis and therapy of lung cancer

1978 • 130 citations

Explant culture of human colon

1978 • 127 citations

Changing Distribution of Primary Cancers in the Large Bowel

1977 • 126 citations

Metabolism of benzo(a)pyrene and identification of the major benzo(a)pyrene-DNA adducts in cultured human colon.

1978 • 107 citations

Metabolism of benzo[a]pyrene by cultured tracheobronchial tissues from mice, rats, hamsters, bovines and humans

1980 • 102 citations

Changes in site distribution of colorectal carcinoma in Connecticut, 1940–1973

1977 • 89 citations

1,2-Dimethylhydrazine-induced methylation of DNA bases in various rat organs and the effect of pretreatment with disulfiram.

1979 • 88 citations

Modification of DNA by aflatoxin B1 creates alkali-labile lesions in DNA at positions of guanine and adenine.

1978 • 84 citations

Metabolism of aflatoxin B1 and identification of the major aflatoxin B1-DNA adducts formed in cultured human bronchus and colon.

1979 • 75 citations

Metabolism of benzo(a)pyrene, N-nitrosodimethylamine, and N-nitrosopyrrolidine and identification of the major carcinogen-DNA adducts formed in cultured human esophagus.

1979 • 70 citations

Aflatoxin—Human Colon Carcinogenesis?

1976 • 68 citations

Metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in cultured human bronchus and pancreatic duct.

1977 • 65 citations

Separation of water-soluble metabolites of benzo[a]pyrene formed by cultured human colon

1979 • 62 citations

Formation and loss of alkylated purines from DNA of hamster liver after administration of dimethylnitrosamine.

1979 • 53 citations

Explant culture of rat colon: A model system for studying metabolism of chemical carcinogens

1978 • 50 citations

DNA alkylation in mice with genetically different susceptibility to 1,2-dimethylhydrazine-induced colon carcinogenesis.

1978 • 46 citations

Metabolism of Acyclic and Cyclic N-Nitrosamines in Cultured Human Bronchi2

1977 • 40 citations

Binding of Chemical Carcinogens to Macromolecules in Cultured Human Colon: Brief Communication2

1977 • 39 citations

Formation and removal of aflatoxin B1-induced DNA lesions in epithelioid human lung cells.

1979 • 38 citations

Alkylated purines in the DNA of various rat tissues after administration of 1,2-dimethylhydrazine

1977 • 38 citations

Association and dissociation of the Ah locus with the metabolism of aflatoxin B1 by mouse liver. Co-segregation of aflatoxin B1 hydroxylase induction with aryl hydrocarbon (benzo(a)pyrene) hydroxylase induction.

1978 • 38 citations

Effect of Lifetime Exposure to Aflatoxin B 1 in Rats 2

1975 • 34 citations

Metabolism of Acyclic and Cyclic N-Nitrosamines by Cultured Human Colon

1978 • 34 citations

Metabolism of Benzo[a]pyrene in Cultured Human Tissues and Cells

1978 • 20 citations

Chapter 16 Quantitative Light Microscopic Autoradiography

1974 • 20 citations

Effect of various chemicals on the metabolism of benzo(a)pyrene by cultured rat colon

1977 • 19 citations

Studies of Ultrastructure, Cytochemistry, and Organ Culture of Human Bronchial Epithelium

1974 • 18 citations

Intestinal carcinogenesis in rats using 1,2-dimethylhydrazine with or without degraded carrageenan

1975 • 16 citations

The evolving role of computerized tomography in radiation oncology

1977 • 15 citations

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