Modification of DNA by aflatoxin B1 creates alkali-labile lesions in DNA at positions of guanine and adenine.

A new method for sequencing DNA.

1977 • 7,941 citations

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

1975 • 3,362 citations

Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

1973 • 2,275 citations

METHODS IN CANCER RESEARCH

1969 • 1,197 citations

Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids.

1975 • 1,030 citations

Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro.

1977 • 507 citations

The Nucleotide Sequence of the lac Operator

1973 • 480 citations

Construction of a colicin E1-R factor composite plasmid in vitro: means for amplification of deoxyribonucleic acid

1975 • 449 citations

The Chemical Effects ofNucleic Acid Alkylation and Their Relation to Mutagenesis and Carcinogen esis

1975 • 446 citations

Liver microsomal metabolism of aflatoxin B 1 to a reactive derivative toxic to Salmonella typhimurium TA 1530.

1972 • 415 citations

2,3-Dihydro-2-(guan-7-yl)-3-hydroxy-aflatoxin B1, a major acid hydrolysis product of aflatoxin B1-DNA or -ribosomal RNA adducts formed in hepatic microsome-mediated reactions and in rat liver in vivo.

1977 • 260 citations

Aflatoxin B1-2,3-oxide as a probable intermediate in the covalent binding of aflatoxins B1 and B2 to rat liver DNA and ribosomal RNA in vivo.

1977 • 252 citations

Organic Chemistry of Nucleic Acids

1972 • 250 citations

The Nucleotide Sequence of the Lactose Messenger Ribonucleic Acid Transcribed from the UV5 Promoter Mutant of Escherichia coli

1973 • 214 citations

Aflatoxin B1-2,3-oxide: Evidence for its formation in rat liver in vivo and by human liver microsomes in vitro

1974 • 213 citations

The role of aflatoxin metabolism in its toxic lesion

1976 • 212 citations

K-region and non-K-region metabolism of benzo(a)pyrene by rat liver microsomes.

1973 • 143 citations

2,3-Dihydro-2,3-dihydroxy-aflatoxin B1: An acid hydrolysis product of an RNA-aflatoxin B1 adduct formed by hamster and rat liver microsomes in vitro

1973 • 128 citations

The reactivity and carcinogenicity of aflatoxin B1-2,3-dichloride, a model for the putative 2,3-oxide metabolite of aflatoxin B1.

1975 • 117 citations

Induction of Mutations in DNA-repair Deficient Bacteria by a Liver Microsomal Metabolite of Aflatoxin B1

1973 • 91 citations

Formation of a factor lethal for S. Typhimurium TA1530 and TA1531 on incubation of aflatoxin B1 with rat liver microsomes

1971 • 73 citations

The nature of mutants in the lac promoter region

1968 • 73 citations

Reduction III binding of [14C] aflatoxin B1 to rat liver macromolecules by phenobarbitone pretreatment

1975 • 64 citations

Binding of [14C]aflatoxin B1 to cellular macromolecules in the rat and hamster

1975 • 64 citations

Aflatoxin B1 metabolism to aflatoxicol and derivatives lethal to Bacillus subtilis GSY 1057 by rainbow trout (Salmo gairdneri) liver.

1976 • 36 citations