A transdominant tat mutant that inhibits tat-induced gene expression from the human immunodeficiency virus long terminal repeat.

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

1983 • 6,811 citations

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

1984 • 3,647 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Cellular uptake of the tat protein from human immunodeficiency virus

1988 • 2,690 citations

Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein

1988 • 1,488 citations

Isolation of Lymphocytopathic Retroviruses from San Francisco Patients with AIDS

1984 • 1,429 citations

Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product

1987 • 902 citations

Trans -Activator Gene of Human T-Lymphotropic Virus Type III (HTLV-III)

1985 • 872 citations

The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat

1985 • 825 citations

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

1989 • 742 citations

Activation of the AIDS Retrovirus Promoter by the Cellular Transcription Factor, Sp1

1986 • 741 citations

Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism

1986 • 730 citations

HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA

1986 • 673 citations

Tat trans-activates the human immunodeficiency virus through a nascent RNA target

1989 • 644 citations

A second post-transcriptional trans-activator gene required for HTLV-III replication

1986 • 639 citations

The trans-activator gene of HTLV-III is essential for virus replication

1986 • 635 citations

The trans-activator gene of the human T cell lymphotropic virus type III is required for replication

1986 • 615 citations

HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation

1989 • 577 citations

Location of the Trans -Activating Region on the Genome of Human T-Cell Lymphotropic Virus Type III

1985 • 558 citations

HIV-1 tat trans-activation requires the loop sequence within tar

1988 • 551 citations

Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitro.

1989 • 472 citations

Tat Protein from Human Immunodeficiency Virus Forms a Metal-Linked Dimer

1988 • 464 citations

Structural and functional characterization of human immunodeficiency virus tat protein

1989 • 444 citations

Intracellular immunization

1988 • 420 citations

Trans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA viruses.

1986 • 368 citations

Structure, sequence, and position of the stem-loop in tar determine transcriptional elongation by tat through the HIV-1 long terminal repeat.

1989 • 357 citations

Post-transcriptional regulation accounts for the trans-activation of the human T-lymphotropic virus type III

1986 • 325 citations

Elevated levels of mRNA can account for the trans-activation of human immunodeficiency virus.

1986 • 303 citations

HIV-1 Gag mutants can dominantly interfere with the replication of the wild-type virus

1989 • 299 citations

Human immunodeficiency virus type 1 LTR TATA and TAR region sequences required for transcriptional regulation.

1989 • 275 citations

Structural arrangements of transcription control domains within the 5'-untranslated leader regions of the HIV-1 and HIV-2 promoters.

1988 • 271 citations

A discrete element 3' of human immunodeficiency virus 1 (HIV-1) and HIV-2 mRNA initiation sites mediates transcriptional activation by an HIV trans activator.

1988 • 270 citations

Mutational analysis of the conserved basic domain of human immunodeficiency virus tat protein

1989 • 270 citations

Alternative Mechanisms for Activation of Human Immunodeficiency Virus Enhancer in T Cells

1988 • 265 citations

Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear events.

1987 • 246 citations

Mutational analysis of HIV-1 Tat minimal domain peptides: Identification of trans-dominant mutants that suppress HIV-LTR-driven gene expression

1989 • 244 citations

Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat

1988 • 235 citations

Purification of the human immunodeficiency virus type 1 enhancer and TAR binding proteins EBP-1 and UBP-1.

1988 • 201 citations

Functional domains required for tat-induced transcriptional activation of the HIV-1 long terminal repeat.

1988 • 193 citations

The nuclear migration signal of Xenopus laevis nucleoplasmin.

1987 • 176 citations

Expression of a truncated viral trans-activator selectively impedes lytic infection by its cognate virus

1988 • 169 citations

Transcriptional Control of the Mouse Prealbumin (Transthyretin) Gene: Both Promoter Sequences and a Distinct Enhancer Are Cell Specific

1986 • 149 citations

HIV-1 TAT “activates” presynthesized RNA in the nucleus

1989 • 135 citations

Specific binding of a HeLa cell nuclear protein to RNA sequences in the human immunodeficiency virus transactivating region.

1989 • 121 citations

Activity of synthetic peptides from the Tat protein of human immunodeficiency virus type 1.

1989 • 96 citations

Missense mutations in an infectious human immunodeficiency viral genome: functional mapping of tat and identification of the rev splice acceptor.

1988 • 91 citations

An adenovirus type 5 E1A protein with a single amino acid substitution blocks wild-type E1A transactivation.

1987 • 34 citations

HTLV x Gene Mutants Exhibit Novel Transcriptional Regulatory Phenotypes

1987 • 30 citations

An Adenovirus Type 5 ElA Protein with a Single Amino Acid Substitution Blocks Wild-Type ElA Transactivation

1987 • 15 citations