Chemokines – linking receptors to response

Involvement of chemokine receptors in breast cancer metastasis

2001 • 5,203 citations

Chemokines

2000 • 3,773 citations

International union of pharmacology. XXII. Nomenclature for chemokine receptors.

2000 • 1,771 citations

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

1990 • 1,531 citations

CXCR4-activated astrocyte glutamate release via TNFα: amplification by microglia triggers neurotoxicity

2001 • 1,024 citations

Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defense cytokines.

1987 • 983 citations

The mucosal immune system: from fundamental concepts to vaccine development

1992 • 912 citations

Inhibition of Bacterial Adherence by Secretory Immunoglobulin A: A Mechanism of Antigen Disposal

1972 • 760 citations

A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo

2000 • 643 citations

The CXC Chemokine Receptor 2, CXCR2, Is the Putative Receptor for ELR+ CXC Chemokine-Induced Angiogenic Activity

2000 • 565 citations

Purification and amino acid sequencing of NAF, a novel neutrophil-activating factor produced by monocytes

1987 • 513 citations

Serum and nasal wash antibodies associated with resistance to experimental challenge with influenza A wild-type virus

1986 • 428 citations

Chemokine receptor homo- or heterodimerization activates distinct signaling pathways

2001 • 423 citations

Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1α is mediated by the chemokine receptor CXCR4

1998 • 419 citations

Chemokines and T Lymphocytes

1998 • 403 citations

Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4.

1995 • 392 citations

Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to beta-thromboglobulin.

1988 • 357 citations

CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neurons

1997 • 327 citations

Passive transfer of local immunity to influenza virus infection by IgA antibody.

1991 • 322 citations

Cross‐protection in mice infected with influenza A virus by the respiratory route is correlated with local IgA antibody rather than serum antibody or cytotoxic T cell reactivity

1984 • 320 citations

Cutting Edge: A Novel Chemokine Ligand for CCR10 And CCR3 Expressed by Epithelial Cells in Mucosal Tissues

2000 • 310 citations

A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity

1997 • 305 citations

Expression Cloning of the STRL33/BONZO/TYMSTR Ligand Reveals Elements of CC, CXC, and CX3C Chemokines

2001 • 303 citations

Identification of a Novel Chemokine (CCL28), which Binds CCR10 (GPR2)

2000 • 285 citations

Overview of the Mucosal Immune System

1989 • 272 citations

Defense mechanisms involving Fc-dependent functions of immunoglobulin A and their subversion by bacterial immunoglobulin A proteases

1988 • 270 citations

New model for analysis of mucosal immunity: intestinal secretion of specific monoclonal immunoglobulin A from hybridoma tumors protects against Vibrio cholerae infection

1991 • 257 citations

Protection of germ-free mice from infection by Helicobacter felis after active oral or passive IgA immunization

1993 • 257 citations

Monocyte Chemoattractant Protein-1 Enhances Gene Expression and Synthesis of Matrix Metalloproteinase-1 in Human Fibroblasts by an Autocrine IL-1α Loop

2000 • 248 citations

Immunoglobulin A mediation of murine nasal anti-influenza virus immunity

1991 • 229 citations

Effects of the neutrophil-activating peptide NAP-2, platelet basic protein, connective tissue-activating peptide III and platelet factor 4 on human neutrophils.

1989 • 224 citations

Cutting Edge: Identification of a Novel Chemokine Receptor That Binds Dendritic Cell- and T Cell-Active Chemokines Including ELC, SLC, and TECK

2000 • 202 citations

Chemokine Receptor Expression and Signaling in Macaque and Human Fetal Neurons and Astrocytes: Implications for the Neuropathogenesis of AIDS

1999 • 202 citations

Virus-neutralizing antibodies of immunoglobulin G (IgG) but not of IgM or IgA isotypes can cure influenza virus pneumonia in SCID mice

1995 • 200 citations

Targeted Deletion of the IgA Constant Region in Mice Leads to IgA Deficiency with Alterations in Expression of Other Ig Isotypes

1999 • 194 citations

Chemokines Regulate IL-6 and IL-8 Production by Fibroblast-Like Synoviocytes from Patients with Rheumatoid Arthritis

2001 • 190 citations

Target frequency and integration pattern for insertion and replacement vectors in embryonic stem cells.

1991 • 187 citations

Expression of functional CXCR4 chemokine receptors on human colonic epithelial cells

1999 • 176 citations

Outcome of Influenza Infection: Effect of Site of Initial Infection and Heterotypic Immunity

1980 • 164 citations

Expression and growth-promoting function of the IL-8 receptor beta in human melanoma cells.

1996 • 149 citations

Synergistic action of cholera toxin B subunit (and Escherichia coli heat-labile toxin B subunit) and a trace amount of cholera whole toxin as an adjuvant for nasal influenza vaccine

1994 • 148 citations

Mechanisms of heterosubtypic immunity to lethal influenza A virus infection in fully immunocompetent, T cell-depleted, beta2-microglobulin-deficient, and J chain-deficient mice.

1997 • 142 citations

Mucosal Immunity to Influenza Without IgA: An IgA Knockout Mouse Model

1999 • 141 citations

Antibody-Independent Protective Mucosal Immunity to Gastric Helicobacter Infection in Mice

1999 • 140 citations

Human Vascular Smooth Muscle Cells Express Receptors for CC Chemokines

1998 • 138 citations

Lack of J Chain Inhibits the Transport of Gut IgA and Abrogates the Development of Intestinal Antitoxic Protection

1999 • 137 citations

IgA Deficiency**This article was accepted for publication on 17 January 1997.

1997 • 133 citations

Novel neutrophil-stimulating peptides

1989 • 129 citations

Cutting Edge: Expression of the C-C Chemokine Receptor CCR3 in Human Airway Epithelial Cells

2001 • 117 citations

IgA and mucosal defense

1995 • 114 citations

Strategies for the induction of immune responses at mucosal surfaces making use of cholera toxin B subunit as immunogen, carrier, and adjuvant.

1994 • 107 citations

The Role of Th1 and Th2 Cells for Mucosal IgA Responsesa

1996 • 100 citations

Secretory immunological response after intranasal inactivated influenza A virus vaccinations: evidence for immunoglobulin A memory

1983 • 93 citations

CCR11 Is a Functional Receptor for the Monocyte Chemoattractant Protein Family of Chemokines

2000 • 91 citations

IgA class switch in I alpha exon-deficient mice. Role of germline transcription in class switch recombination.

1996 • 90 citations

IgA Immunodeficiency Leads to Inadequate Th Cell Priming and Increased Susceptibility to Influenza Virus Infection

2001 • 88 citations

Immunoglobulin levels in saliva in individuals with selective IgA deficiency: Compensatory IgM secretion and its correlation with HLA and susceptibility to infections

1989 • 86 citations

RANTES promotes growth and survival of human first-trimester forebrain astrocytes

2001 • 80 citations

Severity of infections in IgA deficiency: correlation with decreased serum antibodies to pneumococcal polysaccharides and decreased serum IgG2 and/or IgG4

1995 • 72 citations

Helicobacter pylori infections in IgA deficiency: lack of role for the secretory immune system

1996 • 65 citations

Target Frequency and Integration Pattern for Insertion and Replacement Vectors in Embryonic Stem Cells

1991 • 64 citations

Melanoma growth stimulatory activity enhances the phosphorylation of the class II interleukin-8 receptor in non-hematopoietic cells.

1994 • 64 citations

Prevention of influenza by the intranasal administration of cold-recombinant, live-attenuated influenza virus vaccine: importance of interferon-γ production and local IgA response

1995 • 63 citations

The heterogeneity of IgA deficiency

1988 • 55 citations

Immunity to vaginal HSV‐2 infection in immunoglobulin A knockout mice

1998 • 53 citations

Induction and Assessment of Immunity at Enteromucosal Surfaces in Humans: Implications for Vaccine Development

1993 • 46 citations

Intracellular Neutralization of Sendai and Influenza Viruses by IgA Monoclonal Antibodies

1995 • 41 citations

The significance of IgG subclasses and mannan-binding lectin (MBL) for susceptibility to infection in apparently healthy adults with IgA deficiency

1999 • 40 citations

Adaptive Immune Response to Shigella flexneri 2a cydC in Immunocompetent Mice and Mice Lacking Immunoglobulin A

1999 • 33 citations

IgG subclass deficiency with or without IgA deficiency

1991 • 32 citations

Corrective Effects of Interleukin-12 on Age-Related Deficiencies in IFN-gammaProduction and IL-12Rbeta2 Expression in Virus-Specific CD8⁺T Cells

2000 • 31 citations

IgA deficiency.

1997 • 28 citations

Mechanism of enhancement of the immune responses to influenza vaccine with cholera toxin B subunit and a trace amount of holotoxin

1995 • 22 citations

Influenza A subtype cross-protection after immunization of outbred mice with a purified chimeric NS1/HA2 influenza virus protein

1994 • 21 citations

Compensatory levels of salivary IgM anti-Streptococcus mutans antibodies in IgA-deficient patients.

1995 • 19 citations

THE ABILITY OF IgA TO INHIBIT COMPLEMENT CONSUMPTION BY COMPLEMENT-FIXING ANTIGENS AND ANTIGEN-ANTIBODY COMPLEXES

1984 • 10 citations