Abnormal Multimeric and Oligomeric Composition Is Associated With Enhanced Endothelial Expression of von Willebrand Factor in Pulmonary Hypertension

Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies

1966 • 4,504 citations

The Pathology of Hypertensive Pulmonary Vascular Disease

1958 • 1,242 citations

Involvement of large plasma von Willebrand factor (vWF) multimers and unusually large vWF forms derived from endothelial cells in shear stress-induced platelet aggregation.

1986 • 609 citations

The complex multimeric composition of factor VIII/von Willebrand factor

1981 • 572 citations

Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor.

1987 • 571 citations

Swainsonine inhibits the biosynthesis of complex glycoproteins by inhibition of Golgi mannosidase II.

1982 • 463 citations

Shear-induced platelet aggregation requires von Willebrand factor and platelet membrane glycoproteins Ib and IIb-IIIa

1987 • 291 citations

Pulmonary artery endothelial abnormalities in patients with congenital heart defects and pulmonary hypertension. A correlation of light with scanning electron microscopy and transmission electron microscopy.

1986 • 191 citations

Determination of the von Willebrand's disease antigen (factor VIII-related antigen) in plasma by quantitative immunoelectrophoresis.

1975 • 183 citations

Initial glycosylation and acidic pH in the Golgi apparatus are required for multimerization of von Willebrand factor.

1986 • 164 citations

Structure-function relationship of human von Willebrand factor

1987 • 164 citations

Primary Pulmonary Hypertension

1987 • 137 citations

Structure-function relationship of human von Willebrand factor

1987 • 131 citations

Von Willebrand factor promotes endothelial cell adhesion via an Arg-Gly-Asp-dependent mechanism.

1989 • 112 citations

Abnormal endothelial factor VIII associated with pulmonary hypertension and congenital heart defects.

1987 • 108 citations

Characteristics of surviving and nonsurviving patients with primary pulmonary hypertension

1984 • 107 citations

Multimeric structure of platelet factor VIII/von Willebrand factor: the presence of larger multimers and their reassociation with thrombin- stimulated platelets

1982 • 103 citations

Detection of a Platelet-Agglutinating Factor in Thrombotic Thrombocytopenic Purpura

1984 • 97 citations

von Willebrand factor abnormalities in primary pulmonary hypertension.

1987 • 72 citations

Abnormalities in von Willebrand factor and antithrombin III after cardiopulmonary bypass operations for congenital heart disease

1992 • 71 citations

Endothelial cell-derived high molecular weight von Willebrand factor is converted into the plasma multimer pattern by granulocyte proteases

1989 • 37 citations

Von Willebrand Factor Multimer Patterns in Pregnancy-Induced Hypertension

1989 • 36 citations

Sialic acid prevents loss of large von Willebrand factor multimers by protecting against amino-terminal proteolytic cleavage

1988 • 35 citations

Evidence for local platelet activation in pulmonary vessels in patients with pulmonary hypertension secondary to chronic obstructive pulmonary disease

1991 • 29 citations

Supranormal von Willebrand factor multimers in scleroderma

1989 • 28 citations

The von Willebrand Factor Gene and Genetics of von Willebrand's Disease

1991 • 27 citations

Supranormal von Willebrand factor multimers in scleroderma

1989 • 21 citations

Effect of Intentional Hemodilution on Platelet Survival in Secondary Pulmonary Hypertension

1989 • 17 citations

von Willebrand Factor Multimer Analysis Using a Sensitive Peroxidase Staining Method

1989 • 12 citations

Scanning electron microscopic characterization of circulating platelet aggregates in pulmonary hypertension

1992 • 1 citations