Determination of clozapine and its N-demethylated metabolite in plasma by use of gas chromatography-mass spectrometry with single ion detection

Antipsychotic Drugs, Neurotransmitters, and Schizophrenia

1978 • 500 citations

Effect of clozapine on the turnover of dopamine in the corpus striatum and in the limbic system

1973 • 296 citations

Tolerability and therapeutic effect of clozapine

1985 • 277 citations

The effect of long‐term treatment with clozapine in schizophrenia: A retrospective study in 96 patients treated with clozapine for up to 13 years

1988 • 249 citations

Agranulocytosis during treatment with clozapine

1977 • 229 citations

CLOZAPINE AND HALOPERIDOL IN A SINGLE‐BLIND CROSS‐OVER TRIAL: THERAPEUTIC AND BIOCHEMICAL ASPECTS IN THE TREATMENT OF SCHIZOPHRENIA

1974 • 198 citations

Plasma Level Monitoring of Antipsychotic Drugs Clinical Utility

1986 • 147 citations

Clozapine, Chlorpromazine, and Placebo in Newly Hospitalized, Acutely Schizophrenic Patients

1979 • 146 citations

Effects of clozapine on cerebral catecholaminergic neurone systems

1972 • 126 citations

Plasma Level Monitoring of Antipsychotic Drugs

1978 • 110 citations

Ergebnisse eines Doppelblindversuches von HF 1854^*(8-Chlor-11-(4-methyl-1-piperazinyl)-5H-dibenzo (b, e) (1,4) diazepin) im Vergleich zu Levomepromazin

1971 • 90 citations

Clozapine (Leponex) compared with chlorpromazine: a double-blind evaluation of pharmacological and clinical properties.

1974 • 71 citations

Antipsychotic drugs, neurotransmitters, and schizophrenia

1978 • 64 citations

Measurement of plasma levels of tricyclic psychoactive drugs and their metabolites by UV reflectance photometry of thin layer chromatograms

1976 • 52 citations

Long-term effect of clozapine in schizophrenia a retrospective study of 108 chronic schizophrenics treated with clozapine for up to 7 years

1986 • 49 citations

The metabolism of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e) (1,4)diazepine (clozapine) in mice, dogs and human subjects.

1971 • 47 citations

Clozapine treatment of schizophrenic patients ‐ PLASMA CONCENTRATION AND COAGULATION FACTORS

1977 • 43 citations

[Effect profile of a chemically new broad spectrum neuroleptic of the dibenzo-diazepine group].

1966 • 40 citations

[Exchange of aromatically bound halogen for OH- and SCH3-groups in metabolising clozapine in the human organism (author's transl)].

1977 • 22 citations