Role of G proteins in shear stress-mediated nitric oxide production by endothelial cells

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Diversity of G Proteins in Signal Transduction

1991 • 1,990 citations

Flow-induced release of endothelium-derived relaxing factor

1986 • 1,379 citations

Flow Effects on Prostacyclin Production by Cultured Human Endothelial Cells

1985 • 1,237 citations

Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator.

1991 • 529 citations

Role of calcium and calmodulin in flow-induced nitric oxide production in endothelial cells

1994 • 520 citations

Shear stress-induced release of nitric oxide from endothelial cells grown on beads.

1991 • 488 citations

Shear stress induced stimulation of mammalian cell metabolism

1988 • 370 citations

Fluid shear stress modulates cytosolic free calcium in vascular endothelial cells

1992 • 355 citations

Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production

1990 • 343 citations

Differential role of extra‐ and intracellular calcium in the release of EDRF and prostacyclin from cultured endothelial cells

1988 • 321 citations

EDRF-mediated shear-induced dilation opposes myogenic vasoconstriction in small rabbit arteries

1991 • 239 citations

Pertussis toxin inhibits endothelium‐dependent relaxations to certain agonists in porcine coronary arteries.

1989 • 167 citations

Shear‐induced platelet‐derived growth factor gene expression in human endothelial cells is mediated by protein kinase C

1992 • 134 citations

Shear stress induced membrane currents and calcium transients in human vascular endothelial cells

1992 • 94 citations

Modulation of NO and endothelin by chronic increases in blood flow in canine femoral arteries

1992 • 94 citations

Flow‐induced prostacyclin production is mediated by a pertussis toxin‐sensitive G protein

1992 • 80 citations

GTP gamma S loading of endothelial cells stimulates phospholipase C and uncouples ATP receptors

1988 • 51 citations

Release of endothelium‐derived relaxing factor from pig cultured aortic endothelial cells, as assessed by changes in endothelial cell cyclic GMP content, is inhibited by a phorbol ester

1990 • 45 citations

Pertussis toxin reduces endothelium-dependent and independent responses to alpha-2- adrenergic stimulation in systemic canine arteries and veins.

1991 • 36 citations

Effect of sodium fluoride on cytosolic free Ca2+- concentrations and cGMP-levels in endothelial cells

1990 • 35 citations

Role of intracellular thiols in release of EDRF from cultured endothelial cells

1992 • 34 citations

Phospholipase C activity in NCB-20 cells is inhibited by protein kinase A-mediated phosphorylation of low molecular mass GTP-binding proteins.

1990 • 32 citations

Pertussis toxin inhibits endothelium-dependent relaxations evoked by fluoride

1990 • 27 citations

Identification, partial purification, and characterization of two guanosine triphosphate-binding proteins associated with insulin receptors.

1992 • 25 citations

Histamine and bradykinin stimulate the phosphoinositide turnover in human umbilical vein endothelial cells via different G‐proteins

1989 • 25 citations

Guanosine 5′-O-(3-thiotriphosphate) causes endothelium-dependent, pertussis toxin-sensitive relaxations in porcine coronary arteries

1992 • 16 citations

Two types of G proteins involved in regulation of phosphoinositide turnover in pulmonary endothelial cells

1991 • 13 citations