Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

Cancer statistics, 2000

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Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

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An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

1996 • 3,094 citations

Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis

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AP-1 as a regulator of cell life and death

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TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB

1996 • 2,665 citations

Suppression of TNF-α-Induced Apoptosis by NF-κB

1996 • 2,623 citations

Caspase-3 Is Required for DNA Fragmentation and Morphological Changes Associated with Apoptosis

1998 • 1,927 citations

Reduced Apoptosis and Cytochrome c–Mediated Caspase Activation in Mice Lacking Caspase 9

1998 • 1,642 citations

Activation of Transcription Factor NF-κB Is Suppressed by Curcumin (Diferuloylmethane)

1995 • 1,352 citations

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

1991 • 1,223 citations

Antioxidant activity of curcumin and related compounds

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Cytochrome c: Can't Live with It—Can't Live without It

1997 • 768 citations

Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-κB activation via the NIK/IKK signalling complex

1999 • 638 citations

Curcumin Blocks Cytokine-Mediated NF-κB Activation and Proinflammatory Gene Expression by Inhibiting Inhibitory Factor I-κB Kinase Activity

1999 • 616 citations

NF-κB Induces Expression of the Bcl-2 Homologue A1/Bfl-1 To Preferentially Suppress Chemotherapy-Induced Apoptosis

1999 • 574 citations

Tumor Necrosis Factor Induces Bcl-2 and Bcl-x Expression through NFκB Activation in Primary Hippocampal Neurons

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Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

1998 • 531 citations

Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation.

1989 • 473 citations

Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines

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Ionizing radiation induces expression and binding activity of the nuclear factor kappa B.

1991 • 410 citations

Curcumin, an antioxidant and anti-tumor promoter, induces apoptosis in human leukemia cells

1996 • 405 citations

Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells.

1991 • 381 citations

Antiproliferative effect of curcumin (diferuloylmethane) against human breast tumor cell lines

1997 • 349 citations

Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo

2001 • 316 citations

Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines

1996 • 279 citations

Effect of curcumin on cell cycle progression and apoptosis in vascular smooth muscle cells

1998 • 225 citations

Curcumin mediated apoptosis in AK‐5 tumor cells involves the production of reactive oxygen intermediates

1999 • 218 citations

Curcumin Induces a p53-Dependent Apoptosis in Human Basal Cell Carcinoma Cells

1998 • 212 citations

Effect of dietary curcumin and dibenzoylmethane on formation of 7,12- dimethylbenz[a]anthracene-induced mammary tumors and lymphomas/leukemias in Sencar mice

1998 • 198 citations

Antitumor activity of curcumin is mediated through the induction of apoptosis in AK‐5 tumor cells

1999 • 184 citations

The Dietary Pigment Curcumin Reduces Endothelial Tissue Factor Gene Expression by Inhibiting Binding of AP-1 to the DNA and Activation of NF-κB

1997 • 165 citations

A Novel Apoptosis-like Pathway, Independent of Mitochondria and Caspases, Induced by Curcumin in Human Lymphoblastoid T (Jurkat) Cells

1999 • 132 citations

Inhibition of proliferation and apoptosis of human and rat T lymphocytes by curcumin, a curry pigment

1997 • 113 citations

Requirement of the Caspase-3/CPP32 Protease Cascade for Apoptotic Death following Cytokine Deprivation in Hematopoietic Cells

1997 • 103 citations

Didox (A Novel Ribonucleotide Reductase Inhibitor) Overcomes bcl-2 Mediated Radiation Resistance in Prostate Cancer Cell Line PC-3

2002 • 101 citations

Curcumin inhibits the proliferation and cell cycle progression of human umbilical vein endothelial cell

1996 • 97 citations

Apoptosis and the response to anticancer therapy

2001 • 90 citations

Attitudes and Use of Complementary Medicine in Men with Prostate Cancer

2002 • 89 citations

Bcl-Xshort is elevated following severe global ischemia in rat brains

1997 • 83 citations

Transformation reversion induced in JB6 RT101 cells by AP-1 inhibitors

1995 • 83 citations

EGR-1 Induction Is Required for Maximal Radiosensitivity in A375-C6 Melanoma Cells

1996 • 69 citations

Par-4, A Pro-Apoptotic Gene, Inhibits Radiation-Induced NFκB Activity and Bcl-2 Expression Leading to Induction of Radiosensitivity in Human Prostate Cancer Cells PC-3

2002 • 63 citations