The mRNA Closed-loop Model: The Function of PABP and PABP-interacting Proteins in mRNA Translation

eIF4 Initiation Factors: Effectors of mRNA Recruitment to Ribosomes and Regulators of Translation

1999 • 2,096 citations

Regulation of translation initiation by FRAP/mTOR

2001 • 1,532 citations

Circularization of mRNA by Eukaryotic Translation Initiation Factors

1998 • 940 citations

Crystal structure at 1.92 Å resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin

1994 • 827 citations

The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency.

1991 • 795 citations

A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initation of hepatitis C and classical swine fever virus RNAs

1998 • 706 citations

Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G.

1996 • 679 citations

Human eukaryotic translation initiation factor 4G (eIF4G) recruits Mnk1 to phosphorylate eIF4E

1999 • 635 citations

The Transcription Factor Associated Ccr4 and Caf1 Proteins Are Components of the Major Cytoplasmic mRNA Deadenylase in Saccharomyces cerevisiae

2001 • 574 citations

The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation

1989 • 561 citations

A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation

1998 • 560 citations

mRNA Silencing in Erythroid Differentiation: hnRNP K and hnRNP E1 Regulate 15-Lipoxygenase Translation from the 3′ End

1997 • 501 citations

TIA-1 is a translational silencer that selectively regulates the expression of TNF-α

2000 • 498 citations

Recognition of Polyadenylate RNA by the Poly(A)-Binding Protein

1999 • 494 citations

mRNA polyadenylate-binding protein: gene isolation and sequencing and identification of a ribonucleoprotein consensus sequence.

1986 • 455 citations

A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability.

1987 • 401 citations

A common function for mRNA 5' and 3' ends in translation initiation in yeast.

1995 • 374 citations

Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation

1998 • 369 citations

Evidence that all messenger RNA molecules (except histone messenger RNA) contain poly(A) sequences and that the poly(A) has a nuclear function

1972 • 354 citations

mRNA poly(A) tail, a 3' enhancer of translational initiation.

1990 • 353 citations

Modulation of the Fate of Cytoplasmic mRNA by AU-Rich Elements: Key Sequence Features Controlling mRNA Deadenylation and Decay

1997 • 352 citations

Mechanism of ribosome recruitment by hepatitis C IRES RNA

2001 • 349 citations

A Protein of Molecular Weight 78,000 Bound to the Polyadenylate Region of Eukaryotic Messenger RNAs

1973 • 347 citations

Rotavirus RNA-binding protein NSP3 interacts with eIF4GI and evicts the poly(A) binding protein from eIF4F

1998 • 338 citations

Translation initiation factor eIF4G mediates in vitro poly(A) tail-dependent translation

1997 • 314 citations

RNA RECOGNITION BY RNP PROTEINS DURING RNA PROCESSING

1998 • 299 citations

A Mechanism for Translationally Coupled mRNA Turnover

2000 • 289 citations

Cap-dependent and cap-independent translation by internal initiation of mRNAs in cell extracts prepared from Saccharomyces cerevisiae.

1994 • 274 citations

Translation Initiation Factors eIF-iso4G and eIF-4B Interact with the Poly(A)-binding Protein and Increase Its RNA Binding Activity

1997 • 261 citations

Identification of TIAR as a Protein Binding to the Translational Regulatory AU-rich Element of Tumor Necrosis Factor α mRNA

1999 • 256 citations

Selective Degradation of Early-Response-Gene mRNAs: Functional Analyses of Sequence Features of the AU-Rich Elements

1994 • 253 citations

The Eukaryotic Polypeptide Chain Releasing Factor (eRF3/GSPT) Carrying the Translation Termination Signal to the 3′-Poly(A) Tail of mRNA

1999 • 252 citations

Lipoxygenase mRNA Silencing in Erythroid Differentiation

2001 • 251 citations

The mRNA Poly(A)-Binding Protein: Localization, Abundance, and RNA-Binding Specificity

1994 • 245 citations

Multiple portions of poly(A)-binding protein stimulate translation in vivo

2000 • 228 citations

A novel protein with RNA-binding motifs interacts with ataxin-2

2000 • 218 citations

The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities.

1991 • 218 citations

XenopusPoly(A) Binding Protein: Functional Domains in RNA Binding and Protein – Protein Interaction

1996 • 214 citations

Translational Repression by a Novel Partner of Human Poly(A) Binding Protein, Paip2

2001 • 209 citations

Picornavirus IRESes and the poly(A) tail jointly promote cap-independent translation in a mammalian cell-free system

2000 • 204 citations

Translation Initiation and Ribosomal Biogenesis: Involvement of a Putative rRNA Helicase and RPL46

1990 • 204 citations

Structure and function of the C-terminal PABC domain of human poly(A)-binding protein

2001 • 199 citations

RNA—protein complexes

1996 • 192 citations

Physical Association of Eukaryotic Initiation Factor 4G (eIF4G) with eIF4A Strongly Enhances Binding of eIF4G to the Internal Ribosomal Entry Site of Encephalomyocarditis Virus and Is Required for Internal Initiation of Translation

2000 • 190 citations

Tob, a novel protein that interacts with p185erbB2, is associated with anti-proliferative activity.

1996 • 190 citations

Transcription of the Vaccinia Virus Genome and the Occurrence of Polyriboadenylic Acid Sequences in Messenger RNA

1970 • 187 citations

Efficient Translation of Rotavirus mRNA Requires Simultaneous Interaction of NSP3 with the Eukaryotic Translation Initiation Factor eIF4G and the mRNA 3′ End

2000 • 182 citations

Tales of poly(A): a review

1990 • 171 citations

Selective degradation of early-response-gene mRNAs: functional analyses of sequence features of the AU-rich elements.

1994 • 165 citations

Possible Involvement of poly(A) in protein synthesks

1983 • 160 citations

Dual Interactions of the Translational Repressor Paip2 with Poly(A) Binding Protein

2001 • 156 citations

Translational control during early dictyostelium development: Possible involvement of poly(A) sequences

1984 • 141 citations

Recent advances in RNA–protein recognition

2001 • 134 citations

Wheat Germ Poly(A) Binding Protein Enhances the Binding Affinity of Eukaryotic Initiation Factor 4F and (iso)4F for Cap Analogues

1998 • 133 citations

An Internal Polypyrimidine-Tract-Binding Protein-Binding Site in the Hepatitis C Virus RNA Attenuates Translation, Which Is Relieved by the 3′-Untranslated Sequence

1999 • 131 citations

The yeast poly(A)-binding protein Pab1p stimulates invitro poly(A)-dependent and cap-dependent translation by distinct mechanisms

1999 • 127 citations

Interaction of eIF4G with poly(A)-binding protein stimulates translation and is critical for Xenopus oocyte maturation

2000 • 126 citations

Evidence that the SKI antiviral system of Saccharomyces cerevisiae acts by blocking expression of viral mRNA.

1993 • 116 citations

1 Origins and Principles of Translational Control

2007 • 116 citations

Circular polysomes predominate on the rough endoplasmic reticulum of somatotropes and mammotropes in the rat anterior pituitary

1987 • 114 citations

Functional hierarchy of AUUUA motifs in mediating rapid interleukin-3 mRNA decay.

1994 • 109 citations

ANA, a novel member of Tob/BTG1 family, is expressed in the ventricular zone of the developing central nervous system

1998 • 107 citations

Rotavirus protein NSP3 (NS34) is bound to the 3' end consensus sequence of viral mRNAs in infected cells

1993 • 101 citations

Disruption of the Interaction of Mammalian Protein Synthesis Eukaryotic Initiation Factor 4B with the Poly(A)-binding Protein by Caspase- and Viral Protease-mediated Cleavages

2001 • 100 citations

The translational capacity of deadenylated ovalbumin messenger RNA

1976 • 100 citations

Linking the 3′ Poly(A) Tail to the Subunit Joining Step of Translation Initiation: Relations of Pab1p, Eukaryotic Translation Initiation Factor 5B (Fun12p), and Ski2p-Slh1p

2001 • 91 citations

The poly(A)‐binding protein facilitates in vitro translation of poly(A)‐rich mRNA

1988 • 84 citations

X-ray structure of the human hyperplastic discs protein: An ortholog of the C-terminal domain of poly(A)-binding protein

2001 • 84 citations

The expansion of the CAG repeat in ataxin-2 is a frequent cause of autosomal dominant spinocerebellar ataxia

1997 • 74 citations

Wheat Germ Poly(A)-binding Protein Increases the ATPase and the RNA Helicase Activity of Translation Initiation Factors eIF4A, eIF4B, and eIF-iso4F

2000 • 70 citations

Translational Silencing of Ceruloplasmin Requires the Essential Elements of mRNA Circularization: Poly(A) Tail, Poly(A)-Binding Protein, and Eukaryotic Translation Initiation Factor 4G

2001 • 63 citations

Association of ANA, a Member of the Antiproliferative Tob Family Proteins, with a Cafl Component of the CCR4 Transcriptional Regulatory Complex

2001 • 36 citations

Structure and function of rotavirus nonstructural protein NSP3

1996 • 12 citations