Translational Silencing of Ceruloplasmin Requires the Essential Elements of mRNA Circularization: Poly(A) Tail, Poly(A)-Binding Protein, and Eukaryotic Translation Initiation Factor 4G

eIF4 Initiation Factors: Effectors of mRNA Recruitment to Ribosomes and Regulators of Translation

1999 • 2,096 citations

Regulating the fate of mRNA: The control of cellular iron metabolism

1993 • 1,233 citations

Circularization of mRNA by Eukaryotic Translation Initiation Factors

1998 • 940 citations

Mechanism and regulation of mRNA polyadenylation

1997 • 762 citations

Evidence that Tristetraprolin Binds to AU-Rich Elements and Promotes the Deadenylation and Destabilization of Tumor Necrosis Factor Alpha mRNA

1999 • 725 citations

Starting at the Beginning, Middle, and End: Translation Initiation in Eukaryotes

1997 • 685 citations

Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G.

1996 • 679 citations

The Possible Significance of the Ferrous Oxidase Activity of Ceruloplasmin in Normal Human Serum

1966 • 672 citations

Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux

1999 • 572 citations

A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation

1998 • 560 citations

The intracellular localization of messenger RNAs

1995 • 534 citations

mRNA Silencing in Erythroid Differentiation: hnRNP K and hnRNP E1 Regulate 15-Lipoxygenase Translation from the 3′ End

1997 • 501 citations

TIA-1 is a translational silencer that selectively regulates the expression of TNF-α

2000 • 498 citations

Translation of Vascular Endothelial Growth Factor mRNA by Internal Ribosome Entry: Implications for Translation under Hypoxia

1998 • 496 citations

Binding of a Cytosolic Protein to the Iron-Responsive Element of Human Ferritin Messenger RNA

1988 • 363 citations

Copper Proteins and Copper Enzymes

1980 • 341 citations

Life and death in the cytoplasm: messages from the 3′ end

1997 • 335 citations

Translation initiation factor eIF4G mediates in vitro poly(A) tail-dependent translation

1997 • 314 citations

A Mechanism for Translationally Coupled mRNA Turnover

2000 • 289 citations

Familial apoceruloplasmin deficiency associated with blepharospasm and retinal degeneration

1987 • 289 citations

IRP-1 Binding to Ferritin mRNA Prevents the Recruitment of the Small Ribosomal Subunit by the Cap-Binding Complex eIF4F

1998 • 281 citations

Translation of 15-lipoxygenase mRNA is inhibited by a protein that binds to a repeated sequence in the 3′ untranslated region.

1994 • 267 citations

The Eukaryotic Polypeptide Chain Releasing Factor (eRF3/GSPT) Carrying the Translation Termination Signal to the 3′-Poly(A) Tail of mRNA

1999 • 252 citations

Lipoxygenase mRNA Silencing in Erythroid Differentiation

2001 • 251 citations

The STAR protein, GLD-1, is a translational regulator of sexual identity in Caenorhabditis elegans

1999 • 246 citations

The mRNA Poly(A)-Binding Protein: Localization, Abundance, and RNA-Binding Specificity

1994 • 245 citations

Multiple portions of poly(A)-binding protein stimulate translation in vivo

2000 • 228 citations

15 Translational Control of Developmental Decisions

2000 • 222 citations

The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities.

1991 • 218 citations

Stress-activated Protein Kinases (JNK and p38/HOG) Are Essential for Vascular Endothelial Growth Factor mRNA Stability

2000 • 183 citations

Complex Contribution of the 3′-Untranslated Region to the Expressional Regulation of the Human Inducible Nitric-oxide Synthase Gene

2000 • 181 citations

Pbp1p, a Factor Interacting withSaccharomyces cerevisiaePoly(A)-Binding Protein, Regulates Polyadenylation

1998 • 178 citations

FOG-2, a novel F-box containing protein, associates with the GLD-1 RNA binding protein and directs male sex determination in the C. elegans hermaphrodite germline

2000 • 171 citations

Dual Interactions of the Translational Repressor Paip2 with Poly(A) Binding Protein

2001 • 156 citations

Transcriptional regulation of ceruloplasmin gene expression during inflammation.

1988 • 154 citations

From factors to mechanisms: translation and translational control in eukaryotes

1999 • 150 citations

Cap-Poly(A) Synergy in Mammalian Cell-free Extracts

2000 • 149 citations

Eukaryotic translation initiation: there are (at least) two sides to every story.

2000 • 138 citations

Translational control of dosage compensation in Drosophila by Sex-lethal: cooperative silencing via the 5' and 3' UTRs of msl-2 mRNA is independent of the poly(A) tail

1999 • 128 citations

Interaction of eIF4G with poly(A)-binding protein stimulates translation and is critical for Xenopus oocyte maturation

2000 • 126 citations

Participation of the human p53 3′UTR in translational repression and activation following γ-irradiation

1997 • 120 citations

Biochemical characterisation of cap-poly(A) synergy in rabbit reticulocyte lysates: the eIF4G-PABP interaction increases the functional affinity of eIF4E for the capped mRNA 5'-end

2000 • 114 citations

Regulation of translation by specific protein/mRNA interactions

1994 • 110 citations

Induction of ceruloplasmin synthesis by IFN-gamma in human monocytic cells.

1997 • 91 citations

Control of the Translational Efficiency of β-ATPase mRNA Depends on the Regulation of a Protein That Binds the 3′ Untranslated Region of the mRNA

1997 • 91 citations

X-ray structure of the human hyperplastic discs protein: An ortholog of the C-terminal domain of poly(A)-binding protein

2001 • 84 citations

1 Origins and Targets of Translational Control

1996 • 82 citations

Delayed Translational Silencing of Ceruloplasmin Transcript in Gamma Interferon-Activated U937 Monocytic Cells: Role of the 3′ Untranslated Region

1999 • 66 citations

The MEF2A 3′ Untranslated Region Functions as a cis-Acting Translational Repressor

1997 • 59 citations

Translational Control

2008 • 55 citations

Ribosome Concentration Contributes to Discrimination against Poly(A)− mRNA during Translation Initiation in Saccharomyces cerevisiae

1997 • 37 citations

Rapid Deadenylation and Poly(A)-Dependent Translational Repression Mediated by the Caenorhabditis elegans tra-2 3′ Untranslated Region in Xenopus Embryos

2000 • 35 citations

Identification of a GA-rich Sequence as a Protein-binding Site in the 3′-Untranslated Region of Chicken Elastin mRNA with a Potential Role in the Developmental Regulation of Elastin mRNA Stability

2000 • 33 citations

A GG Nucleotide Sequence of the 3′ Untranslated Region of Amyloid Precursor Protein mRNA Plays a Key Role in the Regulation of Translation and the Binding of Proteins

2000 • 32 citations