Toxicity of expanded polyglutamine‐domain proteins in Escherichia coli

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

1993 • 7,941 citations

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

1991 • 2,763 citations

CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1

1994 • 1,698 citations

Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1

1993 • 1,596 citations

Unstable expansion of CAG repeat in hereditary dentatorubral–pallidoluysian atrophy (DRPLA)

1994 • 1,122 citations

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease

1993 • 1,084 citations

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

1992 • 964 citations

Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p

1994 • 721 citations

Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias

1995 • 646 citations

A huntingtin-associated protein enriched in brain with implications for pathology

1995 • 597 citations

SCA1 transgenic mice: A model for neurodegeneration caused by an expanded CAG trinucleotide repeat

1995 • 582 citations

Expanded polyglutamine in the Machado–Joseph disease protein induces cell death in vitro and in vivo

1996 • 546 citations

Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in E. coli

1995 • 353 citations

Expression analysis of the ataxin–1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals

1995 • 294 citations

When more is less: Pathogenesis of glutamine repeat neurodegenerative diseases

1995 • 263 citations

Trinucleotide repeat expansion in neurological disease

1994 • 185 citations

Strong correlation between the number of CAG repeats in androgen receptor genes and the clinical onset of features of spinal and bulbar muscular atrophy

1992 • 185 citations

Toxicity of an overproduced foreign gene product in Escherichia coli and its use in plasmid vectors for the selection of transcription terminators

1984 • 172 citations

Abnormal gene product identified in hereditary dentatorubral–pallidoluysian atrophy (DRPLA) brain

1995 • 160 citations

Stability of an expanded trinucleotide repeat in the androgen receptor gene in transgenic mice

1995 • 138 citations

Absence of Disease Phenotype and Intergenerational Stability of the Cag Repeat in Transgenic Mice Expressing the Human Huntington Disease Transcript

1996 • 111 citations

Analysis of the SCAI CAG repeat in a large number of families with dominant ataxia: Clinical and molecular correlations

1995 • 84 citations

Molecular cloning of a full-length cDNA for dentatorubral-pallidoluysian atrophy and regional expressions of the expanded alleles in the CNS.

1995 • 81 citations

CAG trinucleotide RNA repeats interact with RNA-binding proteins.

1996 • 45 citations

The difficulty of cloning Streptococcus pneumoniae mal and ami loci in Escherichia coli: toxicity of malX and antiA gene products

1989 • 33 citations

Molecular cloning, sequencing and expression of cytochrome c2 from Rhodospirillum rubrum

1990 • 21 citations