Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites.
Data up to Jan 2025
Total Citations Per Year
Abstract
References (61)
Cadherin Cell Adhesion Receptors as a Morphogenetic Regulator
1991 • 3,314 citations
Epidermal Growth Factor
1979 • 2,964 citations
Signal transduction from the extracellular matrix.
1993 • 1,727 citations
Epidermal growth factor.
1990 • 1,645 citations
The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species.
1989 • 1,393 citations
FIBRONECTIN AND ITS RECEPTORS
1988 • 1,336 citations
Peptide Growth Factors and Their Receptors
1991 • 1,221 citations
A Heparin-Binding Growth Factor Secreted by Macrophage-Like Cells That Is Related to EGF
1991 • 1,135 citations
Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene.
1993 • 912 citations
A 130K protein from chicken gizzard: Its localization at the termini of microfilament bundles in cultured chicken cells
1979 • 794 citations
Epiligrin, a new cell adhesion ligand for integrin α3β1 in epithelial basement membranes
1991 • 771 citations
Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the SId mutant
1991 • 740 citations
The isolation and characterization of the human helper inducer T cell subset.
1985 • 708 citations
CELL ADHESION MOLECULES: Implications for a Molecular Histology
1991 • 707 citations
MEMBRANE-ANCHORED GROWTH FACTORS
1993 • 676 citations
The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell-cell and cell-substrate adhesion of human epidermal cells.
1990 • 629 citations
Structure and Function of Human Amphiregulin: A Member of the Epidermal Growth Factor Family
1989 • 586 citations
Expression cloning of a diphtheria toxin receptor: Identity with a heparin-binding EGF-like growth factor precursor
1992 • 552 citations
The TGF-α precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction
1989 • 482 citations
The function of multiple extracellular matrix receptors in mediating cell adhesion to extracellular matrix: preparation of monoclonal antibodies to the fibronectin receptor that specifically inhibit cell adhesion to fibronectin and react with platelet glycoproteins Ic-IIa.
1988 • 446 citations
Cadherins
1992 • 437 citations
Transmembrane TGF-α precursors activate EGF/TGF-α receptors
1989 • 432 citations
p60v-src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system.
1993 • 421 citations
A nonsecretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact
1990 • 409 citations
Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line.
1994 • 405 citations
Betacellulin: a mitogen from pancreatic beta cell tumors
1993 • 392 citations
Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrins.
1990 • 391 citations
Molecular cloning of integrin-associated protein: an immunoglobulin family member with multiple membrane-spanning domains implicated in alpha v beta 3-dependent ligand binding.
1993 • 380 citations
P-24: a human leukemia-associated and lymphohemopoietic progenitor cell surface structure identified with monoclonal antibody.
1981 • 371 citations
Novel function for beta 1 integrins in keratinocyte cell-cell interactions.
1990 • 338 citations
Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junctions where the level of tyrosine phosphorylation is elevated.
1991 • 310 citations
Diphtheria Toxin Binds to the Epidermal Growth Factor (EGF)-like Domain of Human Heparin-binding EGF-like Growth Factor/Diphtheria Toxin Receptor and Inhibits Specifically Its Mitogenic Activity
1995 • 302 citations
The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor.
1995 • 298 citations
Diphtheria Toxin and Related Proteins
1973 • 285 citations
Suppression of cell motility and metastasis by transfection with human motility-related protein (MRP-1/CD9) DNA.
1993 • 284 citations
Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity.
1994 • 266 citations
Kalinin is more efficient than laminin in promoting adhesion of primary keratinocytes and some other epithelial cells and has a different requirement for integrin receptors.
1994 • 252 citations
Changes in membrane-microfilament interaction in intercellular adherens junctions upon removal of extracellular Ca2+ ions.
1986 • 225 citations
Interaction of integrins alpha 3 beta 1 and alpha 2 beta 1: potential role in keratinocyte intercellular adhesion.
1993 • 210 citations
Identification of the motility-related protein (MRP-1), recognized by monoclonal antibody M31-15, which inhibits cell motility.
1991 • 189 citations
A novel integrin beta subunit is associated with the vitronectin receptor alpha subunit (alpha v) in a human osteosarcoma cell line and is a substrate for protein kinase C.
1989 • 167 citations
The function and distinctive regulation of the integrin VLA-3 in cell adhesion, spreading, and homotypic cell aggregation.
1993 • 164 citations
Evidence That Monoclonal Antibodies against CD9 Antigen Induce Specific Association between CD9 and the Platelet Glycoprotein IIb-IIIa Complex
1989 • 153 citations
C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and associate with each other and with CD4 or CD8 in T cells.
1993 • 152 citations
Direct stimulation of cells expressing receptors for macrophage colony- stimulating factor (CSF-1) by a plasma membrane-bound precursor of human CSF-1
1990 • 150 citations
CD9-regulated adhesion. Anti-CD9 monoclonal antibody induce pre-B cell adhesion to bone marrow fibroblasts through de novo recognition of fibronectin.
1994 • 136 citations
Molecular cloning and expression of the cDNA for alpha 3 subunit of human alpha 3 beta 1 (VLA-3), an integrin receptor for fibronectin, laminin, and collagen.
1991 • 135 citations
Growth Factors in Early Embryogenesis
1989 • 119 citations
Integrin expression in cutaneous malignant melanoma: Association of the α3/β1 heterodimer with tumor progression
1993 • 113 citations
The 27-kD diphtheria toxin receptor-associated protein (DRAP27) from vero cells is the monkey homologue of human CD9 antigen: expression of DRAP27 elevates the number of diphtheria toxin receptors on toxin-sensitive cells.
1992 • 106 citations
Expression of the neuroglandular antigen and analogues in melanoma. CD9 expression appears inversely related to metastatic potential of melanoma
1993 • 89 citations
Biochemical evidence for a homophilic interaction of the alpha 3 beta 1 integrin.
1993 • 84 citations
Fibronectin And Its Receptors
1988 • 81 citations
The OX-44 molecule couples to signaling pathways and is associated with CD2 on rat T lymphocytes and a natural killer cell line.
1992 • 71 citations
The Human Cell Surface Glycoprotein Complex (gp 120,200) Recognized by Monoclonal Antibody K20 is a Component Binding to Phytohaemagglutinin on T Cells
1986 • 64 citations
An antibody that inhibits the binding of diphtheria toxin to cells revealed the association of a 27-kDa membrane protein with the diphtheria toxin receptor.
1991 • 57 citations
Detection of Epidermal Growth Factor Receptors and E‐Cadherins in the Basolateral Membrane of A431 Cells by Laser Scanning Fluorescence Microscopy
1991 • 40 citations
Homotypic aggregation of pre-B leukemic cell lines by antibodies to VLA integrins correlates with their expression of CD9.
1993 • 32 citations
Cell Adhesion Molecules: Implications For A Molecular Histology
1991 • 28 citations
Direct stimulation of cells expressing receptors for macrophage colony- stimulating factor (CSF-1) by a plasma membrane-bound precursor of human CSF-1
1990 • 15 citations
Growth Factors In Early Embryogenesis
1989 • 8 citations