Effects of Rofecoxib or Naproxen vs Placebo on Alzheimer Disease Progression

“Mini-mental state”

1975 • 82,784 citations

Clinical diagnosis of Alzheimer's disease

1984 • 27,279 citations

The Clinical Dementia Rating (CDR)

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Longitudinal Data Analysis for Discrete and Continuous Outcomes

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Inflammation and Alzheimer's disease

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A new rating scale for Alzheimer's disease

1984 • 3,948 citations

The Effect of Celecoxib, a Cyclooxygenase-2 Inhibitor, in Familial Adenomatous Polyposis

2000 • 2,505 citations

The Neuropsychiatric Inventory

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The Mini-Mental State Examination

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A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

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Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease

1996 • 1,371 citations

Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease

2001 • 1,183 citations

Risk of Alzheimer's disease and duration of NSAID use

1997 • 1,113 citations

An Inventory to Assess Activities of Daily Living for Clinical Trials in Alzheimerʼs Disease

1997 • 1,088 citations

Clinical trial of indomethacin in Alzheimer's disease

1993 • 996 citations

Ibuprofen Suppresses Plaque Pathology and Inflammation in a Mouse Model for Alzheimer's Disease

2000 • 880 citations

Quality of life in Alzheimer's disease: Patient and caregiver reports.

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Inflammation, autotoxicity and Alzheimer disease

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Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain

1998 • 455 citations

A randomized controlled trial of prednisone in Alzheimer’s disease

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Nonsteroidal anti-inflammatory drugs in Alzheimer's disease

1995 • 442 citations

A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer’s disease

1999 • 393 citations

Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice

2001 • 229 citations

Age-Dependent Cognitive Deficits and Neuronal Apoptosis in Cyclooxygenase-2 Transgenic Mice

2001 • 225 citations

Effect of hydroxychloroquine on progression of dementia in early Alzheimer's disease: an 18-month randomised, double-blind, placebo-controlled study

2001 • 212 citations

Neuronal Cyclooxygenase 2 Expression in the Hippocampal Formation as a Function of the Clinical Progression of Alzheimer Disease

2001 • 200 citations

Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer's Disease neuropathology

2002 • 105 citations

Cyclooxygenase-2 and Presenilin-1 Gene Expression Induced by Interleukin-1β and Amyloid β42 Peptide Is Potentiated by Hypoxia in Primary Human Neural Cells

2002 • 100 citations