The DAP-kinase family of proteins: study of a novel group of calcium-regulated death-promoting kinases

Programmed Cell Death in Animal Development

1997 • 2,690 citations

Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death.

1995 • 574 citations

DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death

2002 • 467 citations

DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity

1997 • 408 citations

DAP kinase links the control of apoptosis to metastasis

1997 • 394 citations

TGF-β induces apoptosis through Smad-mediated expression of DAP-kinase

2001 • 373 citations

DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation

2000 • 353 citations

Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy

2003 • 333 citations

Dap-Kinase Participates in TNF-α–And FAS-Induced Apoptosis and Its Function Requires the Death Domain

1999 • 272 citations

DAP-kinase loss of expression in various carcinoma and B-cell lymphoma cell lines: possible implications for role as tumor suppressor gene

1997 • 207 citations

A Genetic Tool Used to Identify Thioredoxin as a Mediator of a Growth Inhibitory Signal

1991 • 189 citations

The Pro-apoptotic Function of Death-associated Protein Kinase Is Controlled by a Unique Inhibitory Autophosphorylation-based Mechanism

2001 • 150 citations

Death-Associated Protein Kinase-Related Protein 1, a Novel Serine/Threonine Kinase Involved in Apoptosis

2000 • 146 citations

DAP-kinase Participates in TNF-alpha and Fas-induced Apoptosis and Its Function Requires the Death Domain

1999 • 124 citations

Crystal structures of the catalytic domain of human protein kinase associated with apoptosis and tumor suppression.

2001 • 98 citations

Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding

2001 • 71 citations

A functional genetic screen identifies regions at the C-terminal tail and death-domain of death-associated protein kinase that are critical for its proapoptotic activity

2000 • 69 citations