The generation and modulation of endogenous rhythmicity in the aplysia bursting pacemaker neurone R15

A quantitative description of membrane current and its application to conduction and excitation in nerve

1952 • 21,965 citations

Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo

1952 • 2,384 citations

Measurement of current‐voltage relations in the membrane of the giant axon of Loligo

1952 • 1,655 citations

The dual effect of membrane potential on sodium conductance in the giant axon of Loligo

1952 • 1,551 citations

The components of membrane conductance in the giant axon of Loligo

1952 • 1,359 citations

Calcium Channel

1981 • 1,184 citations

Voltage clamp studies of a transient outward membrane current in gastropod neural somata

1971 • 1,122 citations

The neurosciences : a study program

1967 • 952 citations

MORPHOLOGICAL AND FUNCTIONAL PROPERTIES OF IDENTIFIED NEURONS IN THE ABDOMINAL GANGLION OF APLYSIA CALIFORNICA

1967 • 806 citations

Electrogenic sodium pump in nerve and muscle cells.

1972 • 787 citations

CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASES, IV. WIDESPREAD OCCURRENCE OF ADENOSINE 3′,5′-MONOPHOSPHATE-DEPENDENT PROTEIN KINASE IN VARIOUS TISSUES AND PHYLA OF THE ANIMAL KINGDOM

1969 • 775 citations

CALCIUM-DEPENDENT POTASSIUM ACTIVATION IN NERVOUS TISSUES

1978 • 760 citations

Prediction of repetitive firing behaviour from voltage clamp data on an isolated neurone soma

1971 • 752 citations

Physiological and Biochemical Aspects of Nervous Integration

1968 • 740 citations

Possible role for cyclic nucleotides and phosphorylated membrane proteins in postsynaptic actions of neurotransmitters†

1976 • 694 citations

Three pharmacologically distinct potassium channels in molluscan neurones.

1977 • 688 citations

Conduction and selectivity in potassium channels

1983 • 665 citations

Serotonin and cyclic AMP close single K+ channels in Aplysia sensory neurones

1982 • 658 citations

The neurosciences : fourth study program

1979 • 521 citations

Peptides in Neurobiology

1977 • 450 citations

The surprising heart: a review of recent progress in cardiac electrophysiology.

1984 • 429 citations

Two Fast Transient Current Components during Voltage Clamp on Snail Neurons

1971 • 428 citations

Inactivation of Ca conductance dependent on entry of Ca ions in molluscan neurons.

1979 • 397 citations

Presynaptic modulation of voltage-dependent Ca ²⁺ current: Mechanism for behavioral sensitization in Aplysia californica

1978 • 385 citations

Cellular basis of behavior: An introduction to behavioral neurobiology.

1976 • 379 citations

A light and electron microscope study of the abdominal ganglion of Aplysia californica.

1967 • 377 citations

Biology of cholinergic function

1977 • 368 citations

Intracellular calcium injection causes increased potassium conductance in Aplysia nerve cells

1972 • 349 citations

Neurobiology of Invertebrates

1968 • 348 citations

Inward and delayed outward membrane currents in isolated neural somata under voltage clamp

1971 • 332 citations

Structure and function of inhibitory neuronal mechanisms

1969 • 327 citations

Ionic Currents in Molluscan Soma

1980 • 325 citations

Basic mechanisms of the epilepsies

1970 • 322 citations

A voltage‐sensitive persistent calcium conductance in neuronal somata of Helix.

1976 • 304 citations

Calcium‐mediated inactivation of the calcium conductance in caesium‐loaded giant neurones of Aplysia californica.

1981 • 288 citations

Neurotransmitters and their receptors

1980 • 258 citations

Molluscan neuroendocrinology

1984 • 257 citations

Ionic mechanisms and receptor properties underlying the responses of molluscan neurones to 5‐hydroxytryptamine

1974 • 256 citations

Inhibitory and excitatory effects of dopamine on Aplysia neurones

1972 • 254 citations

Abnormal Neuronal Discharges

1979 • 235 citations

A CHOLINERGIC MECHANISM OF INHIBITORY SYNAPTIC TRANSMISSION IN A MOLLUSCAN NERVOUS SYSTEM

1962 • 232 citations

Spontaneous Activity in Isolated Somata of Aplysia Pacemaker Neurons

1968 • 230 citations

Changes in the intracellular concentration of free calcium ions in a pace‐maker neurone, measured with the metallochromic indicator dye arsenazo III.

1978 • 224 citations

Sodium and calcium components of action potentials in Aplysia giant neurone

1968 • 216 citations

Heterosynaptic facilitation in neurones of the abdominal ganglion of Aplysia depilans.

1965 • 211 citations

A Comparative Survey of the Function, Mechanism and Control of Cellular Oscillators

1979 • 208 citations

Direct and common connections among identified neurons in Aplysia.

1967 • 207 citations

Effects of 4-aminopyridine on potassium currents in a molluscan neuron.

1981 • 204 citations

Mechanism of heterosynaptic facilitation in the giant cell of the abdominal ganglion of Aplysia depilans.

1965 • 202 citations

Internal effects of divalent cations on potassium permeability in molluscan neurones.

1979 • 196 citations

A Contribution of an Electrogenic Na+ Pump to Membrane Potential in Aplysia Neurons

1968 • 193 citations

Effects of tetraethylammonium on potassium currents in a molluscan neurons.

1981 • 193 citations

Voltage—current relations in nerve cell membrane of Onchidium verruculatum

1959 • 182 citations

Peptide Regulation of Bursting Pacemaker Activity in a Molluscan Neurosecretory Cell

1974 • 181 citations

Neural control of circulation in Aplysia. I. Motoneurons.

1974 • 180 citations

Aminopyridine block of transient potassium current.

1982 • 174 citations

Negative Resistance Characteristic Essential for the Maintenance of Slow Oscillations in Bursting Neurons

1974 • 174 citations

CHEMICAL, ENZYMATIC AND ULTRASTRUCTURAL CHARACTERIZATION OF 5‐HYDROXYTRYPTAMINE‐CONTAINING NEURONS FROM THE GANGLIA OF APLYSIA CALIFORNICA AND TRITONIA DIOMEDIA

1973 • 172 citations

Stimulation of egg laying by extracts of neuroendocrine cells (bag cells) of abdominal ganglion of Aplysia.

1970 • 172 citations

Functioning of identified neurons and synapses in abdominal ganglion of Aplysia in absence of protein synthesis.

1971 • 172 citations

Potassium conductance and internal calcium accumulation in a molluscan neurone

1980 • 170 citations

Voltage clamp of the Aplysia giant neurone: early sodium and calcium currents

1970 • 170 citations

Choline acetyltransferase in identified neurons of abdominal ganglion of Aplysia californica.

1971 • 170 citations

Requirements for bursting pacemaker potential activity in molluscan neurones

1975 • 168 citations

Electrogenic transport. Fundamental principles and physiological implications.

1984 • 163 citations

Mechanism of frequency‐dependent broadening of molluscan neurone soma spikes.

1979 • 161 citations

Neurobiology of invertebrates : Gastropoda brain

1976 • 161 citations

Calcium Influx in Active Aplysia Neurones detected by Injected Aequorin

1973 • 160 citations

Ca2+ -activated K+ conductance in internally perfused snail neurons is enhanced by protein phosphorylation.

1982 • 158 citations

Bag Cell Control of Egg Laying in Freely Behaving Aplysia

1977 • 157 citations

Aplysia bursting neurons as endogenous oscillators. I. Phase-response curves for pulsed inhibitory synaptic input

1977 • 157 citations

Studies on bursting pacemaker potential activity in molluscan neurons. III. Effects of hormones

1975 • 153 citations

Ionic mechanisms of excitatory, inhibitory, and dual synaptic actions mediated by an identified interneuron in abdominal ganglion of Aplysia.

1971 • 152 citations

Mathematical description of a bursting pacemaker neuron by a modification of the Hodgkin-Huxley equations

1976 • 151 citations

Ion Channels in Cardiac Cell Membranes

1984 • 148 citations

The visceral ganglion of Aplysia Californica

1963 • 146 citations

Neural control of circulation in Aplysia. II. Interneurons.

1974 • 144 citations

Intrasomatic Injection of Radioactive Precursors for Studying Transmitter Synthesis in Identified Neurons of Aplysia californica

1973 • 143 citations

Cholinergic Transmission Mechanisms for both Excitation and Inhibition in Molluscan Central Synapses

1961 • 143 citations

Aequorin response facilitation and intracellular calcium accumulation in molluscan neurones

1980 • 141 citations

Serotonin-induced hyperpolarization of an indentified Aplysia neuron is mediated by cyclic AMP.

1980 • 133 citations

Calcium‐dependent inward current in Aplysia bursting pace‐maker neurones.

1985 • 133 citations

An Atlas of Cellular Oscillators

1979 • 132 citations

Approaches to the cell biology of neurons

1977 • 131 citations

Correlations of neuronal spike discharges produced by monosynaptic connections and by common inputs.

1973 • 131 citations

Ionic requirements for membrane oscillations and their dependence on the calcium concentration in a molluscan pace‐maker neurone

1982 • 130 citations

Bifurcation and resonance in a model for bursting nerve cells

1981 • 130 citations

Multiple, prolonged actions of neuroendocrine bag cells on neurons in Aplysia. I. Effects on bursting pacemaker neurons

1979 • 129 citations

Protein Kinases: Aspects of Their Regulation and Diversity

1973 • 129 citations

Alteration of electrical activity in molluscan neurones by cyclic nucleotides and peptide factors

1976 • 128 citations

The selectivity of ion channels in nerve and muscle

1982 • 128 citations

Prolonged Inhibition in Burst Firing Neurons: Synaptic Inactivation of the Slow Regenerative Inward Current

1978 • 127 citations

The physiological role of three acetylcholine receptors in synaptic transmission in Aplysia

1972 • 123 citations

Neurotransmitter modulation, phosphodiesterase inhibitor effects, and cyclic AMP correlates of afterdischarge in peptidergic neurites

1978 • 123 citations

Temperature Effects on Pacemaker Generation, Membrane Potential, and Critical Firing Threshold in Aplysia Neurons

1967 • 120 citations

Intracellular calcium accumulation during depolarization in a molluscan neurone.

1980 • 120 citations

Multiple, prolonged actions of neuroendocrine bag cells on neurons in Aplysia. II. Effects on beating pacemaker and silent neurons

1979 • 119 citations

Cyclic variation of potassium conductance in a burst‐generating neurone in Aplysia

1973 • 118 citations

Pentobarbital: Selective Depression of Excitatory Postsynaptic Potentials

1973 • 115 citations

Modulation of gated ion channels as a mode of transmitter action

1983 • 115 citations

Serotonin increases an anomalously rectifying K+ current in the Aplysia neuron R15.

1983 • 114 citations

Properties of a facilitating calcium current in pace‐maker neurones of the snail, Helix pomatia.

1976 • 110 citations

Characterization of a chloride conductance activated by hyperpolarization in Aplysia neurones.

1983 • 109 citations

Respiratory pumping: Neuronal control of a centrally commanded behavior in aplysia

1978 • 108 citations

Blockade of voltage-dependent and Ca2+-dependent K+ current components by internal Ba2+ in molluscan pacemaker neurons

1979 • 107 citations

Receptors for gamma-aminobutyric acid (GABA) on aplysia neurons

1978 • 107 citations

Evidence for mediation of a neuronal interaction by a behaviorally active peptide.

1978 • 107 citations

Effect of curare on responses to different putative neurotransmitters in Aplysia neurons

1977 • 106 citations

Light Response of a Giant Aplysia Neuron

1973 • 106 citations

The time courses of intracellular free calcium and related electrical effects after injection of CaCl2 into neurons of the snail,Helix pomatia

1981 • 106 citations

Octopamine: Presence in Single Neurons of Aplysia Suggests Neurotransmitter Function

1974 • 105 citations

Imunocytochemical localization and direct assays of serotonin-containing neurons in Aplysia

1984 • 105 citations

Role of cyclic AMP in a serotonin-evoked slow inward current in snail neurones

1981 • 101 citations

Characteristics of sodium and calcium conductance changes produced by membrane depolarization in an Aplysia neurone.

1979 • 101 citations

Calcium‐induced inactivation of calcium current causes the inter‐burst hyperpolarization of Aplysia bursting neurones.

1985 • 101 citations

The cellular basis of behavior in Aplysia

1971 • 99 citations

Synaptic Activation of an Electrogenic Sodium Pump

1969 • 98 citations

Seventeenth Bowditch lecture. Neural and humoral factors in the temporal organization of behavior.

1973 • 96 citations

Peptides: roles in neuronal excitability.

1976 • 96 citations

Water regulation by a presumptive hormone contained in identified neurosecretory cell R15 of Aplysia.

1976 • 95 citations

Evidence for local hormonal communication between neurones in Aplysia

1978 • 95 citations

�ber sekretorisch t�tige Nervenzellen bei wirbellosen Tieren

1937 • 94 citations

Intracellular injection of protein kinase inhibitor blocks the serotonin-induced increase in K+ conductance in Aplysia neuron R15.

1982 • 93 citations

Experimental Approaches to Understanding the Role of Protein Phosphorylation in the Regulation of Neuronal Function

1983 • 92 citations

Mechanism for shifting the phase of a circadian rhythm by serotonin: involvement of cAMP.

1982 • 91 citations

Aplysia bursting neurons as endogenous oscillators. II. Synchronization and entrainment by pulsed inhibitory synaptic input

1977 • 91 citations

Depolarizing afterpotentials and burst production in molluscan pacemaker neurons

1976 • 90 citations

Differential action of TEA+ on two K+-current components of a molluscan neurone

1972 • 90 citations

Studies on bursting pacemaker potential activity in molluscan neurons. I. Membrane properties and ionic contributions

1975 • 89 citations

cAMP-mediated decrease in K+ conductance evoked by serotonin and dopamine in the same neuron: a biochemical and physiological single-cell study.

1982 • 88 citations

A novel membrane sodium current induced by injection of cyclic nucleotides into gastropod neurones.

1984 • 86 citations

Ionic currents in response to membrane depolarization in an Aplysia neurone.

1979 • 85 citations

Central Neuronal Response to the Activation of Osmoreceptors in the Osphradium of Aplysia

1969 • 84 citations

Intracellular calcium and the control of neuronal pacemaker activity.

1981 • 83 citations

Internal Calcium Changes in a Bursting Pacemaker Neuron Measured with Arsenazo III

1977 • 83 citations

Quantitative aspects of ionic conductance mechanisms contributing to firing pattern of motor cells mediating inking behavior in Aplysia californica

1980 • 82 citations

CHOLINE ACETYLTRANSFERASE IN INDIVIDUAL NEURONS OF APLYSIA CALIFORNICA¹

1970 • 81 citations

Molecular Weight Distribution of Proteins Synthesized in Single, Identified Neurons of Aplysia

1971 • 81 citations

Voltage clamp reveals basis for calcium regulation of bursting pacemaker potentials in Aplysia neurons

1976 • 81 citations

Inactivation without facilitation of calcium conductance in caesium-loaded neurones of Aplysia

1978 • 80 citations

Calcium-Dependent Depression of a Late Outward Current in Snail Neurons

1977 • 79 citations

Voltage and ion dependences of the slow currents which mediate bursting in Aplysia neurone R15.

1985 • 78 citations

Acetylcholinesterase in identified neurons of abdominal ganglion of Aplysia californica.

1971 • 77 citations

Endogenous levels of histamine in single neurons isolated from CNS ofAplysia californica

1975 • 76 citations

Cyclic Nucleotides in the Nervous System

1984 • 76 citations

A non-inactivating inward current recorded during small depolarizing voltage steps in snail pacemaker neurons

1975 • 75 citations

Slow repetitive activity from fast conductance changes in neurons.

1978 • 75 citations

Certain Slow Synaptic Responses: Their Properties and Possible Underlying Mechanisms

1980 • 75 citations

Micro disc electrophoresis in sodium dodecyl sulfate: An application to the study of protein synthesis in individual, identified neurons

1971 • 74 citations

Activation of neurosecretory cells in Aplysia by osphradial stimulation

1969 • 74 citations

Neurones � ondes-salves des mollusques

1974 • 74 citations

Internal Potassium and Chloride Activities and the Effects of Acetylcholine on Identifiable Aplysia Neurones

1971 • 74 citations

Phototransduction in Aplysia Neurons: Calcium Release from Pigmented Granules Is Essential

1975 • 72 citations

Octopamine and phenylethanolamine inAplysia ganglia and in individual neurons

1978 • 71 citations

Active currents in mammalian central neurons

1983 • 71 citations

Endogenous levels of acetylcholine and choline in individual neurons of Aplysia

1973 • 71 citations

Membrane potential produced directly by the Na+ pump in Aplysia neurons

1970 • 69 citations

Action of quinidine on ionic currents of molluscan pacemaker neurons.

1984 • 69 citations

Analysis of ionic conductance mechanisms in motor cells mediating inking behavior in Aplysia californica

1980 • 69 citations

Distribution of serotonin and dopamine receptors in aplysia tissues: Analysis by [3H]LSD binding and adenylate cyclase stimulation

1980 • 68 citations

The morphology of identified neurons in the abdominal ganglion of aplysia californica

1976 • 68 citations

A MORPHOLOGICAL AND FUNCTIONAL STUDY ON A CLUSTER OF IDENTIFIABLE NEUROSECRETORY CELLS IN THE ABDOMINAL GANGLION OF APLYSIA CALIFORNICA

1966 • 67 citations

Low molecular weight specific proteins in identified molluscan neurons. I. Synthesis and storage

1975 • 67 citations

Pacemaker Properties of Completely Isolated Neurones in Aplysia californica

1971 • 66 citations

Mechanism of Prolonged Heterosynaptic Facilitation

1964 • 66 citations

Calcium influx induces a post-tetanic hyperpolarization in Aplysia neurones

1974 • 66 citations

Re-evaluation of the Synaptic Activation of an Electrogenic Sodium Pump

1970 • 66 citations

Prolonged excitatory and inhibitory synaptic modulation of a bursting pacemaker neuron.

1974 • 66 citations

Slow depolarizing and hyperpolarizing currents which mediate bursting in Aplysia neurone R15.

1985 • 64 citations

Specific protein metabolism in identifiable neurons of Aplysia californica

1974 • 64 citations

Prolonged Inhibition of Neurons by Neuroendocrine Cells in Aplysia

1979 • 63 citations

Intracellular calcium measured with calcium‐sensitive micro‐electrodes and Arsenazo III in voltage‐clamped Aplysia neurones.

1984 • 63 citations

Isolated identified Aplysia neurons in cell culture

1981 • 63 citations

Studies on bursting pacemaker potential activity in molluscan neurons. II. Regulation by divalent cations

1975 • 63 citations

Biosynthesis of Neuronal Peptides

1977 • 62 citations

Residual Calcium Ions Depress Activation of Calcium-Dependent Current

1982 • 62 citations

Quantitative differences in the currents of bursting and beating molluscan pace‐maker neurones

1982 • 61 citations

ORCADIAN OSCILLATORS AND PHOTORECEPTORS IN THE GASTROPOD, APLYSIA*

1976 • 58 citations

Processus post-synaptiques d'excitation et d'inhibition dans le soma neuronique de l'aplysie et de l'escargot

1958 • 58 citations

Protein phosphorylation and the regulation of ion channels

1983 • 57 citations

Stimulation of a sodium influx by cAMP in Helix neurons

1983 • 57 citations

Phase plane description of endogenous neuronal oscillators in Aplysia

1981 • 57 citations

Characteristics of Pacemaker Oscillations in Aplysia Neurons

1971 • 57 citations

Cellular Dynamics in Invertebrate Neurosecretory Systems

1977 • 56 citations

A Cl− conductance activated by hyperpolarization in Aplysia neurones

1982 • 56 citations

Synaptic and Hormonal Modulation of A Neuronal Oscillator: A Search for Molecular Mechanisms

1979 • 55 citations

Molluscan nerve cells, from biophysics to behavior

1980 • 55 citations

Different effects of cAMP and cGMP derivatives on the activity of an identified neuron: Biochemical and electrophysiological analysis

1980 • 55 citations

Differences between Pacemaker and Nonpacemaker Neurons of Aplysia on Voltage Clamping

1969 • 53 citations

An arginine vasotocin-like neuropeptide is present in the nervous system of the marine mollusc Aplysia californica

1981 • 53 citations

Low molecular weight specific proteins in identified molluscan neurons. II. Processing, turnover, and transport

1975 • 52 citations

Light-Induced Changes in the Structure of Pigmented Granules in Aplysia Neurons

1975 • 52 citations

Non-uniform Ca2+ buffer distribution in a nerve cell body

1980 • 52 citations

Selectivity of the Ca2+-activated and Light-dependent K+ Channels for Monovalent Cations

1982 • 51 citations

Burst Reset and Frequency Control of the Neuronal Oscillators in the Cardiac Ganglion of the Crab, Portunus Sanguinolentus

1980 • 51 citations

EFFECTS OF CHANGES IN Pco₂ AND Pco₂ ON RHYTHMIC POTENTIALS FROM GIANT NEURONS*

1963 • 50 citations

Opposite Synaptic Actions Mediated by Different Branches of an Identifiable Interneuron in Aplysia

1967 • 50 citations

Potassium ion accumulation near a pace‐making cell of Aplysia

1972 • 50 citations

The effects of calcium++ on bursting neurons. A modeling study

1978 • 50 citations

THE CHARACTERIZATION OF HISTIDINE DECARBOXYLASE AND ITS DISTRIBUTION IN NERVES, GANGLIA AND IN SINGLE NEURONAL CELL BODIES FROM THE CNS OF APLYSIA CALIFORNICA

1977 • 50 citations

Intracellular injection of guanyl nucleotides alters the serotonin-induced increase in potassium conductance in Aplysia neuron R15.

1984 • 49 citations

Time course separation of two inward currents in molluscan neurons

1977 • 48 citations

Ionic and metabolic bases of neuronal thermosensitivity.

1981 • 48 citations

Depression and frequency facilitation at a synapse inAplysia californica: Evidence for regulation by availability of transmitter

1974 • 48 citations

Mechanism of long-lasting synaptic inhibition in Aplysia neuron R15

1980 • 48 citations

The dependence of pacemaker discharge of Aplysia neurons upon Na⁺ and Ca⁺⁺

1970 • 48 citations

Membrane Characteristics of Bursting Pacemaker Neurones in Aplysia

1972 • 48 citations

The effect of temperature on the membrane properties of neurons in the visceral ganglion of Aplysia

1966 • 47 citations

Changes in ionic conductances induced by cAMP in Helix neurons

1984 • 47 citations

Frequency facilitation and post-tetanic potentiation of a unitary synaptic potential inAplysia californica are limited by different processes

1976 • 47 citations

External and internal effects of tetraethylammonium on voltage-dependent and Ca-dependent K+ currents components in molluscan pacemaker neurons

1979 • 46 citations

Serotonin alters the phosphorylation of specific proteins inside a single living nerve cell

1982 • 45 citations

Adenylate cyclase in isolated Helix and Aplysia neuronal cell bodies: stimulation by serotonin and peptide-containing extract

1978 • 45 citations

Electrical Activity of Neurosecretory Terminals and Control of Peptide Hormone Release

1977 • 44 citations

Neurobiology of invertebrates : mechanisms of rhythm regulation

1973 • 44 citations

Gating Currents Associated with Sodium and Calcium Currents in an Aplysia Neuron

1976 • 44 citations

AMINO ACID CONCENTRATIONS IN THE APLYSIA NERVOUS SYSTEM: NEURONS WITH HIGH GLYCINE CONCENTRATIONS

1977 • 44 citations

Tris Buffer Attenuates Acetylcholine Responses in Aplysia Neurons

1977 • 44 citations

Electrical Properties and Temporal Organization in Oscillatory Neurons

1968 • 44 citations

On the mechanism underlying bursting in the Aplysia abdominal ganglion R15 cell

1975 • 42 citations

Ca2+ activated K+ conductance in molluscan neurones

1983 • 42 citations

Development of neurons in the abdominal ganglion of Aplysia californica

1979 • 42 citations

Spike aftercurrents in R15 of Aplysia: their relationship to slow inward current and calcium influx

1984 • 42 citations

Propagating calcium spikes in an axon of Aplysia.

1978 • 41 citations

Prolonged action potentials in Aplysia neurones injected with egta

1974 • 40 citations

Local hormonal modulation of neural activity in Aplysia.

1979 • 39 citations

Increased membrane fluidity implicated in acceleration of decay of post-tetanic potentiation by alcohols

1976 • 39 citations

Reponses anomales a des courants sous-liminaires de certaines membranes somatiques (neurones g�ants d'Helix pomatia)

1971 • 39 citations

Divalent ion currents and the delayed potassium conductance in an Aplysia neurone.

1980 • 39 citations

Studies of dopamine pharmacology in molluscs

1983 • 38 citations

Comparative study of acetylcholine and 5-hydroxytryptamine receptors on single snail neurons.

1969 • 38 citations

Presynaptic modulation of transmitter release by the early outward potassium current inAplysia

1983 • 36 citations

Intraneuronal guanylyl-imidodiphosphate injection mimics long-term synaptic hyperpolarization in Aplysia.

1976 • 36 citations

Two reciprocating current components underlying slow oscillations in Aplysia bursting neurons

1980 • 36 citations

Photoresponses of a sensitive extraretinal photoreceptor in Aplysia.

1979 • 36 citations

INFOLDINGS OF NERVE FIBRE MEMBRANES IN THE OPISTHOBRANCH MOLLUSC APLYSIA CALIFORNICA

1961 • 35 citations

Possible role of acetylcholinesterase in regulation of postsynaptic receptor efficacy at a central inhibitory synapse of Aplysia

1983 • 35 citations

Current-voltage relationships of repetitively firing neurons

1979 • 34 citations

Biosynthesis and processing of presumed neurosecretory proteins in single identified neurons of Aplysia californica

1978 • 34 citations

METABOLISM OF PUTATIVE TRANSMITTERS IN INDIVIDUAL NEURONS OF APLYSIA CALIFORNICA: AROMATIC AMINO ACID DECARBOXYLASE

1972 • 34 citations

Seasonal modulation and non-24-hour entrainment of a circadian rhythm in a single neuron.

1969 • 33 citations

Determination of glutamate and glutamine in individual neurons of Aplysia californica

1973 • 33 citations

Synaptic release of radioactivity after intrasomatic injection of choline-3H into an identified cholinergic interneuron in abdominal ganglion of Aplysia californica.

1974 • 33 citations

Dopamine, serotonin and related compounds: Presynaptic effects on synaptic depression, frequency facilitation, and post-tetanic potentiation at a synapse inAplysia californica

1976 • 33 citations

Mechanisms of long-lasting inhibition of a bursting pacemaker neuron.

1974 • 32 citations

Synaptic regulation of specific protein synthesis in an identified neuron

1974 • 32 citations

Protein synthesis in phenotypically different, single neurons ofAplysia

1974 • 32 citations

Penicillin effects on iontophoretic responses inAplysia californica

1977 • 32 citations

Voltage, temperature and ionic dependence of the slow outward current in Aplysia burst‐firing neurones.

1980 • 32 citations

Sodium and calcium gating currents in an Aplysia neurone.

1979 • 31 citations

Circadian Rhythm of Output from Neurones in the Eye of Aplysia

1977 • 31 citations

Selective Recording and Stimulation of Individual Identified Neurons in Freely Behaving Aplysia

1983 • 30 citations

The role of the electrogenic sodium pump in modulation of pacemaker discharge of Aplysia neurons

1974 • 30 citations

Sodium pump stoichiometry in Aplysia neurones from simultaneous current and tracer measurements

1974 • 30 citations

Time dependence of the calcium-activated potassium current

1981 • 30 citations

Effect of Adenosine 3′,5′-Monophosphate on Neuronal Pacemaker Activity: a Voltage Clamp Analysis

1981 • 29 citations

Cs+ loading reveals Na+-dependent persistent inward current and negative slope resistance region in Aplysia giant neurons.

1982 • 29 citations

Cyclic AMP enhances calcium-dependent potassium current inAplysia neurons

1983 • 29 citations

Neurophysiological aspects of rhythms.

1967 • 29 citations

Dopamine reduces slow outward current and calcium influx in burst- firing neuron R15 of Aplysia

1984 • 28 citations

Sustained Tolerance to a Specific Effect of Ethanol on Posttetanic Potentiation in Aplysia

1976 • 28 citations

Organization of inhibition in abdominal ganglion of Aplysia. 3. Interneurons mediating inhibition.

1969 • 28 citations

Inclusions in the neurons of Aplysia californica (cooper, 1863) (Gastropoda opisthobranchiata)

1963 • 28 citations

Processing of low molecular weight proteins by identified neurons of Aplysia

1976 • 27 citations

Dopamine inhibits burst-firing of neurosecretory cell R 15 in Aplysia californica: establishment of a dose-response relationship.

1980 • 27 citations

Driver potentials and the organization of rhythmic bursting in crustacean ganglia

1984 • 27 citations

Two Different Excitatory Transmitters acting on a Single Molluscan Neurone

1967 • 27 citations

Model predictions of the ionic mechanisms underlying the beating and bursting pacemaker characteristics of molluscan neurons

1976 • 27 citations

GABA mediated excitatory responses on neurons

1977 • 27 citations

Cyclic AMP modulation of a specific ion channel in an identified nerve cell: possible role for protein phosphorylation.

1981 • 27 citations

Localization of neuronal Ca2+ buffering near plasma membrane studied with different divalent cations

1983 • 27 citations

Protein synthesis and nerve cell specificity

1974 • 26 citations

Mechanisms of action of cyclic nucleotides on a bursting pacemaker and silent neuron in aplysia

1981 • 25 citations

Marked prolongation of post-tetanic potentiation at a transition temperature and its adaptation

1975 • 25 citations

Phosphoproteins associated with the regulation of a specific potassium channel in the identified Aplysia neuron R15.

1985 • 24 citations

Ionic Basis of the Photoresponse of Aplysia Giant Neuron: K ⁺ Permeability Increase

1972 • 24 citations

Synaptic depression at a synapse inAplysia californica: Analysis in terms of a material flow model of neurotransmitter

1976 • 24 citations

Morphine and related compounds: evidence that they decrease available neurotransmitter inAplysia californica

1974 • 23 citations

Preferential incorporation of extracellular amino acids into neuronal proteins

1975 • 23 citations

Calcium- and cyclic nucleotide-dependent protein kinases and their substrates in the Aplysia nervous system

1985 • 23 citations

The role of diffusion in the photoresponse of an extraretinal photoreceptor of Aplysia.

1979 • 23 citations

Short-term modulation of endogenous bursting rhythms by monosynaptic inhibition in Aplysia neurons: Effects of contingent stimulation

1977 • 23 citations

Heterosynaptic inhibition modifies the presynaptic plasticities of the transmission process at a synapse inAplysia californica

1976 • 22 citations

Patterns of proteins synthesized in the R15 neuron of Aplysia. Temporal studies and evidence for processing.

1976 • 22 citations

Resting and stimulated values of model parameters governing transmitter release at a synapse inAplysia californica

1976 • 22 citations

Separate serotonin and dopamine receptors modulate the duration of post-tetanic potentiation at an aplysia synapse without affecting other aspects of synaptic transmission

1980 • 22 citations

Effects of calcium and magnesium on facilitation of a unitary synaptic potential in neuron R15 of Aplysia

1974 • 22 citations

Modulation of neuronal activity by peptides and neurotransmitters: possible role of cyclic nucleotides.

1978 • 22 citations

Cholinergic agents affect two receptors that modulate transmitter release at a central synapse in Aplysia californica

1975 • 21 citations

Functional correlates of low molecular weight peptide synthesis inAplysia neurons

1975 • 21 citations

The abdominal ganglion of Aplysia brasiliana: A comparative morphological and electrophysiological study, with notes on A. dactylomela

1976 • 21 citations

Pharmacological studies of a novel dopamine-sensitive receptor mediating burst-firing inhibition of neurosecretory cell R 15 in Aplysia californica.

1981 • 20 citations

Extraocular photoreceptors can entrain the circadian rhythm in the abdominal ganglion ofAplysia

1973 • 20 citations

Calcium influx and poststimulus current during early adaptation in Aplysia giant neurons.

1982 • 19 citations

Neuronal events underlying rhythmic behaviors in invertebrates

1977 • 19 citations

The effects of cyclic nucleotide agents on neurons in Aplysia

1979 • 18 citations

Modulation of synatpic output by the transient outward potassium current in Aplysia

1981 • 18 citations

Synaptic stimulation alters protein phosphorylation in vivo in a single Aplysia neuron

1984 • 18 citations

Modulation of neuronal activity by peptides and neurotransmitters: possible role of cyclic nucleotides.

1978 • 18 citations

Selective modulation and turnover of proteins in identified neurons of Aplysia

1975 • 18 citations

DOES CYCLIC 3′,5′‐ADENOSINE MONOPHOSPHATE ACT AS SECOND MESSENGER IN A VOLTAGE‐DEPENDENT RESPONSE TO 5‐HYDROXYTRYPTAMINE IN Aplysia?

1981 • 17 citations

Metabolic aspects of the rhythmogenesis inAplysia pacemaker neurons

1973 • 17 citations

Membrane currents underlying bursting pacemaker activity and spike frequency adaptation in invertebrates.

1986 • 17 citations

Tetrodotoxin-resistant divalent action potentials in an axon of Aplysia

1977 • 17 citations

[Effect of memantine on membrane properties and postsynaptic potentials in neurons of Aplysia californica].

1982 • 17 citations

Voltage clamp analysis of ethanol effects on pacemaker currents ofAplysia neurons

1983 • 16 citations

Measurement of Electrogenic-Pump Current in Aplysia Neurones with Constant-current and Constant-Voltage Techniques

1978 • 16 citations

Seawater osmolarity influences bursting pacemaker activity in intactAplysia california

1983 • 16 citations

Correlations between temperature effects on behavior inaplysiaand firing patterns of identified neurons

1976 • 15 citations

Neuronal oscillators in aplysia: modulation by serotonin and cyclic AMP

1981 • 15 citations

In vitro tests for a circadian rhythm in the electrical activity of a single neuron inAplysia californica

1975 • 15 citations

A comparison of the 12,000 dalton proteins synthesized byAplysia neurons L11 and R15

1976 • 14 citations

Ionic mechanism of inhibition of long duration in aplysia synapse

1980 • 14 citations

Effects of dopamine on theAplysia burster R15

1984 • 14 citations

Asymmetric distribution of aspartate in ganglia and single neurons of Aplysia

1975 • 14 citations

Alteration of neuronal activity in response to cyclic nucleotide agents in Aplysia

1980 • 13 citations

Effects of alcohols upon pacemaker activity in neurons ofAplysia californica

1982 • 13 citations

Determination of taurine in individual neurones of Aplysia californica

1977 • 13 citations

Current-voltage relations in ILD- or dopamine-stabilized bursting neurone in Aplysia

1976 • 12 citations

Axonal site for impulse initiation and rhythmogenesis in Aplysia pacemaker neurons

1980 • 12 citations

Physiological basis of feeding behavior in Tritonia diomedea. III. Role of depolarizing afterpotentials

1981 • 12 citations

Cyclic AMP induces a voltage-dependent current in neurons of Aplysia californica

1981 • 12 citations

Possible mechanisms underlying bursting pacemaker discharges in invertebrate neurons.

1978 • 12 citations

Introduction to neuronal burst activity.

1977 • 11 citations

Different cholinergic synapses converging onto neurons inAplysia produce the same synaptic action

1980 • 11 citations

Theoretical model of slow-wave membrane potential oscillations in molluscan neurons

1983 • 10 citations

Effects of furosemide on neural mechanisms in aplysia

1981 • 10 citations

Effect of TEA on light emission from aequorin-injected Aplysia central neurons

1979 • 10 citations

Synaptic modulation of endogenous neuronal oscillators.

1977 • 10 citations

Evidence for multiple somatic pools of individual axonally transported proteins.

1980 • 10 citations

The amplitude of post-tetanic potentiation of the EPSP RC1-RC15 in aplysia is modulated by environmental parameters

1979 • 9 citations

Photosensitivity of a bursting pacemaker neuron inAplysia californica

1976 • 9 citations

The modelling of a burst-generating neuron with a field-effect transistor analog

1977 • 9 citations

Action of tetrodotoxin on pacemaker conductances in Aplysia neurons

1982 • 9 citations

Morphine effects on cholinergic synaptic transmission in Aplysia: Evidence for receptor blockade

1976 • 9 citations

Gene Expression and the Diversity of Identified Neurons

1983 • 8 citations

Baclofen modifies via the release of monoamines the synaptic depression, frequency facilitation, and posttetanic potentiation observed at an identified cholinergic synapse of Aplysia californica

1981 • 8 citations

Heterosynaptic stimulation modulates the duration of post-tetanic potentiation at an aplysia synapse without affecting other aspects of synaptic transmission

1980 • 8 citations

Caffeine blocks the delayed K+ outward current of molluscan neurons

1981 • 8 citations

Modulation of repetitive action potentials in molluscan neurons stimulated with alternating currents

1977 • 8 citations

Alteration of protein metabolism in individual, identified neurons from Aplysia

1976 • 8 citations

Functional significance of electrogenic pumps in neurons.

1984 • 7 citations

Effects of hypothalamic peptide hormones on the electrical activity of Aplysia neurons

1980 • 7 citations

Fast K+ activity determinations during outward currents of the neuronal membrane of Helix Pomatia

1976 • 7 citations

Reversible and irreversible effects of Po2 alterations on two groups of Aplysia neurons

1981 • 6 citations

Heterogeneity and processing of low molecular weight protein in cell R15 of Aplysia californica

1977 • 6 citations

Development of intrinsic burst generation in identified neuron R15 ofAplysia

1981 • 6 citations

Presynaptic modulating effects of GABA on depression, facilitation, and posttetanic potentiation of a cholinergic synapse in Aplysia californica

1977 • 6 citations

An oxygen dependent current in Aplysia neurons: An approach to the question of cellular hypoxic adaptation

1975 • 5 citations

A cAMP analogue inhibits compound action potential production and phase shifts the circadian clock in the isolated eye of Aplysia californica

1980 • 5 citations

Participation d'une pompe métabolique au potentiel de repos de neurones d'aplysie.

1970 • 5 citations

Benzodiazepines modify synaptic depression, frequency facilitation and PTP of an identified cholinergic synapse of

1980 • 5 citations

Triplicated bursting neuron R15 in an aplysia abdominal ganglion: Non-symmetrical coupling, common synaptic inputs and response to dopamine

1981 • 5 citations

Long-lasting inhibition of neuron R 15 OF Aplysia: Role of the interneuron II network

1984 • 5 citations

The effects of hemicholinium-3 on synaptic depression, facilitation, and post-tetanic potentiation at an identified synapse of Aplysia californica

1980 • 5 citations

Abolition by noradrenaline of the waving bursting neuronal activity (Br neuron of Aplysia fasciata)

1972 • 5 citations

Synaptic influences on identified neurons in an aberrant parieto-visceral ganglion of Aplysia

1970 • 4 citations

Ba++ induced square-shaped potential waves in molluscan neurones

1977 • 4 citations

Interval analysis of bursting discharges in aplysia neurons

1973 • 4 citations

A study of soma isopotentiality in Aplysia neurons

1977 • 4 citations

A Role for Protein Phosphorylation in the Regulation of Electrical Activity of an Identified Nerve Cell

1983 • 4 citations

Endogenous levels of histidine in histamine-containing neurons and other identified nerve cells of Aplysia californica

1977 • 3 citations

Burst-firing inhibition of cell R 15 in Aplysia californica: Pharmacological studies of the effects of tyramine, β-phenethylamine and D-amphetamine

1982 • 3 citations

Effects of the anticonvulsant, trimethadione, on bursting pacemaker activity and recruitment of inhibition in the abdominal ganglion of Aplysia californica

1978 • 3 citations

Change in spike initiation site in Helix pacemaker neurones

1976 • 3 citations

Electroshock after discharges are related to neuronal oscillability: Neuronal models of Aplysia

1982 • 1 citations

Neuron r15 of aplysia confirmation that ongoing spike activity is influenced by a photically entrained circadian rhythm

1971 • 1 citations

Repetitive activity alters spike initiation locus and conduction velocity inAplysia axons

1984 • 1 citations

Cellular Pacemakers, Vol. 2: Function in Normal and Disease States

1983 • 1 citations

Deleted Work

1955 • 0 citations