In situ class switching and differentiation to IgA-producing cells in the gut lamina propria

Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

2000 • 3,323 citations

Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

2001 • 2,472 citations

Plat-E: an efficient and stable system for transient packaging of retroviruses

2000 • 1,614 citations

Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells

1999 • 1,149 citations

A Primitive T Cell-Independent Mechanism of Intestinal Mucosal IgA Responses to Commensal Bacteria

2000 • 1,085 citations

PEYER'S PATCHES: AN ENRICHED SOURCE OF PRECURSORS FOR I<scp>G</scp>A-PRODUCING IMMUNOCYTES IN THE RABBIT

1971 • 756 citations

Mice deficient for the CD40 ligand

1994 • 753 citations

A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells

1990 • 611 citations

Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes.

1989 • 567 citations

Humoral immune responses in CD40 ligand-deficient mice.

1994 • 541 citations

The Role of Interleukin-6 in Mucosal IgA Antibody Responses in Vivo

1994 • 460 citations

Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses

1997 • 417 citations

T-Independent Immune Response: New Aspects of B Cell Biology

2000 • 413 citations

Transforming growth factor beta induces IgA production and acts additively with interleukin 5 for IgA production.

1989 • 394 citations

Many of the IgA producing plasma cells in murine gut are derived from self-replenishing precursors in the peritoneal cavity

1989 • 351 citations

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching.

1986 • 344 citations

Bone marrow stromal cell lines with lymphopoietic activity express high levels of a pre-B neoplasia-associated molecule

1987 • 254 citations

Circular DNA is excised by immunoglobulin class switch recombination

1990 • 244 citations

High frequency class switching of an lgM⁺ B lymphoma clone CH12F3 to lgA⁺ cells

1996 • 212 citations

A hallmark of active class switch recombination: Transcripts directed by I promoters on looped-out circular DNAs

2001 • 169 citations

Alymphoplasia (aly)-Type Nuclear Factor κB–Inducing Kinase (Nik) Causes Defects in Secondary Lymphoid Tissue Chemokine Receptor Signaling and Homing of Peritoneal Cells to the Gut-Associated Lymphatic Tissue System

2000 • 124 citations

Induction of Germline Transcription in the TCRγ Locus by Stat5

1999 • 120 citations

Generation, expansion, migration and activation of mouse B1 cells

2000 • 96 citations

Transfer of lymphocytes of Peyer's patches between immunoglobulin allotype congenic mice: repopulation of the IgA plasma cells in the gut lamina propria.

1981 • 91 citations

The expression of B cell surface receptors. I. The ontogeny and distribution of the murine B cell IgE Fc receptor.

1988 • 80 citations

Increased Frequency of Surface IgA-Positive Plasma Cells in the Intestinal Lamina Propria and Decreased IgA Excretion in Hyper IgA (HIGA) Mice, a Murine Model of IgA Nephropathy with Hyperserum IgA

2000 • 73 citations

The expression of B cell surface receptors. III. The murine low-affinity IgE Fc receptor is not expressed on Ly 1 or ‘Ly 1-like’ B cells

1991 • 68 citations

Relationship between expression of IgA by Peyer's patch cells and functional IgA memory cells.

1987 • 66 citations

Migration and Differentiation of Autoreactive B-1 Cells Induced by Activated γ/δ T Cells in Antierythrocyte Immunoglobulin Transgenic Mice

2000 • 53 citations

IL-10 selectively regulates murine Ig isotype switching

1996 • 47 citations

CD21highIgMhigh Splenic B Cells Enriched in the Marginal Zone: Distinct Phenotypes and Functions

1999 • 31 citations