T-Independent Immune Response: New Aspects of B Cell Biology

Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

2000 • 3,323 citations

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.

1992 • 2,906 citations

Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor

1999 • 2,574 citations

Activation-Induced Cytidine Deaminase (AID) Deficiency Causes the Autosomal Recessive Form of the Hyper-IgM Syndrome (HIGM2)

2000 • 1,604 citations

Mice Transgenic for Baff Develop Lymphocytic Disorders along with Autoimmune Manifestations

1999 • 1,464 citations

Immune Inhibitory Receptors

2000 • 1,283 citations

C3d of Complement as a Molecular Adjuvant: Bridging Innate and Acquired Immunity

1996 • 1,172 citations

TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease

2000 • 1,171 citations

BLyS: Member of the Tumor Necrosis Factor Family and B Lymphocyte Stimulator

1999 • 1,123 citations

A Primitive T Cell-Independent Mechanism of Intestinal Mucosal IgA Responses to Commensal Bacteria

2000 • 1,085 citations

The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice.

1983 • 810 citations

Origin of Murine B Cell Lineages

1993 • 579 citations

Absence of marginal zone B cells in Pyk-2–deficient mice defines their role in the humoral response

2000 • 537 citations

Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-κb-inducing kinase

1999 • 448 citations

Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses

1997 • 417 citations

Many of the IgA producing plasma cells in murine gut are derived from self-replenishing precursors in the peritoneal cavity

1989 • 351 citations

Positive Selection from Newly Formed to Marginal Zone B Cells Depends on the Rate of Clonal Production, CD19, and btk

2000 • 349 citations

A transgenic model of autoimmune hemolytic anemia.

1992 • 232 citations

Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

2000 • 229 citations

Alymphoplasia (aly)-Type Nuclear Factor κB–Inducing Kinase (Nik) Causes Defects in Secondary Lymphoid Tissue Chemokine Receptor Signaling and Homing of Peritoneal Cells to the Gut-Associated Lymphatic Tissue System

2000 • 124 citations

Monoclonal immunoglobulin A derived from peritoneal B cells is encoded by both germ line and somatically mutated VH genes and is reactive with commensal bacteria

1996 • 104 citations

Generation, expansion, migration and activation of mouse B1 cells

2000 • 96 citations

Autoimmunity-Prone B-L (Cd5 B) Cells, Natural Antibodies and Self Recognition

1993 • 77 citations

Increased Frequency of Surface IgA-Positive Plasma Cells in the Intestinal Lamina Propria and Decreased IgA Excretion in Hyper IgA (HIGA) Mice, a Murine Model of IgA Nephropathy with Hyperserum IgA

2000 • 73 citations

Brazing of Inconel X-750 to stainless steel 304 using induction process

2000 • 35 citations