Immediate-early genes, kindling and long-term potentiation

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Induction of c-fos-like protein in spinal cord neurons following sensory stimulation

1987 • 1,975 citations

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1983 • 1,952 citations

Expression of c- fos Protein in Brain: Metabolic Mapping at the Cellular Level

1988 • 1,916 citations

Mapping Patterns of c- fos Expression in the Central Nervous System After Seizure

1987 • 1,771 citations

The Molecular Genetics of Cancer

1987 • 1,729 citations

Fos and jun: The AP-1 connection

1988 • 1,597 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

Human Proto-Oncogene c- jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

1987 • 1,353 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain

1985 • 1,294 citations

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1988 • 1,278 citations

Hereditary cancer, oncogenes, and antioncogenes.

1985 • 1,261 citations

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1988 • 1,256 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

1988 • 1,084 citations

The long and the short of long–term memory—a molecular framework

1986 • 1,026 citations

Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation

1989 • 1,014 citations

Role of ion flux in the control of c-fos expression

1986 • 1,006 citations

Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element

1988 • 983 citations

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1984 • 949 citations

Synaptic Reorganization in the Hippocampus Induced by Abnormal Functional Activity

1988 • 912 citations

Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc.

1987 • 888 citations

Protein blotting: Principles and applications

1983 • 858 citations

DNA binding activities of three murine Jun proteins: Stimulation by Fos

1988 • 850 citations

The role of the leucine zipper in the fos–jun interaction

1988 • 836 citations

Stimulation of Neuronal Acetylcholine Receptors Induces Rapid Gene Transcription

1986 • 761 citations

A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences.

1988 • 733 citations

The Action of Oncogenes in the Cytoplasm and Nucleus

1985 • 708 citations

Induction of proto-oncogene JUN/AP-1 by serum and TPA

1988 • 689 citations

Fos-Associated Protein p39 Is the Product of the jun Proto-Oncogene

1988 • 643 citations

Transcriptional autoregulation of the proto-oncogene fos

1988 • 630 citations

Viral myb oncogene encodes a sequence-specific DNA-binding activity

1988 • 608 citations

The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.

1989 • 601 citations

Kindling stimulation induces c-fos protein(s) in granule cells of the rat dentate gyrus

1987 • 579 citations

Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

1988 • 578 citations

Differential expression of myc family genes during murine development

1986 • 542 citations

The Fos Complex and Fos-Related Antigens Recognize Sequence Elements That Co ntain AP-1 Binding Sites

1988 • 532 citations

fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen.

1988 • 518 citations

fos-associated cellular p39 is related to nuclear transcription factor AP-1

1988 • 508 citations

Anisomycin blocks the late phase of long-term potentiation in the dentate gyrus of freely moving rats

1984 • 508 citations

Superinduction of c- fos by Nerve Growth Factor in the Presence of Peripherally Active Benzodiazepines

1985 • 478 citations

Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain

1988 • 455 citations

Expression and amplification of the N-myc gene in primary retinoblastoma

1984 • 451 citations

Induction of protooncogene c-jun by serum growth factors.

1988 • 438 citations

Convulsant-induced increase in transcription factor messenger RNAs in rat brain.

1988 • 377 citations

Expression of the c-myb proto-oncogene during cellular proliferation

1986 • 360 citations

Deregulated c-fos expression interferes with normal bone development in transgenic mice

1987 • 337 citations

Immunocytochemical localization of calcium/calmodulin-dependent protein kinase II in rat brain.

1984 • 292 citations

In situ hybridization histochemistry and immunocytochemistry reveal an increase in spinal dynorphin biosynthesis in a rat model of peripheral inflammation and hyperalgesia.

1988 • 292 citations

Heterogeneous localization of protein kinase C in rat brain: autoradiographic analysis of phorbol ester receptor binding

1986 • 267 citations

Activation of N-methyl-D-aspartate receptors parallels changes in cellular and synaptic properties of dentate gyrus granule cells after kindling

1988 • 261 citations

Memories of fos

1987 • 253 citations

Oncogenes in development

1987 • 250 citations

Viral and cellular fos proteins are complexed with a 39,000-dalton cellular protein.

1985 • 249 citations

2-Aminopurine Selectively Inhibits the Induction of β-Interferon, c- fos , and c- myc Gene Expression

1988 • 233 citations

Brain injury induces c-fos protein(s) in nerve and glial-like cells in adult mammalian brain

1988 • 223 citations

Axonal migration of protein and glycoprotein to nerve endings. I. Radioautographic analysis of the renewal of protein in nerve endings of chicken ciliary ganglion after intracerebral injection of [3H]lysine

1973 • 220 citations

Generalized seizures induce c-fos protein(s) in mammalian neurons

1987 • 212 citations

The Fos Protein Complex Is Associated with DNA in Isolated Nuclei and Binds to DNA Cellulose

1986 • 206 citations

v-jun encodes a nuclear protein with enhancer binding properties of AP-1

1988 • 196 citations

The fos Oncogene

1987 • 196 citations

Long-term potentiation and the induction of c-fos mRNA and proteins in the dentate gyrus of unanesthetized rats

1989 • 185 citations

The kindled amygdala model of epilepsy: anticonvulsant action of amino acid antagonists

1983 • 180 citations

Anticonvulsant action of a non-competitive antagonist of NMDA receptors (MK-801) in the kindling model of epilepsy

1989 • 179 citations

Polymyxin B, an inhibitor of protein kinase C, prevents the maintenance of synaptic long-term potentiation in hippocampal CA1 neurons

1988 • 178 citations

Delayed c-fos proto-oncogene expression in the rat hippocampus induced by transient global cerebral ischemia: an in situ hybridization study

1989 • 178 citations

Expression of N-myc in teratocarcinoma stem cells and mouse embryos

1985 • 173 citations

Long-term potentiation and kindling: How similar are the mechanisms?

1989 • 172 citations

Differential regulation of neuropeptide and proto-oncogene mRNA content in the hippocampus following recurrent seizures

1987 • 168 citations

Long-lasting and sequential increase of c-fos oncoprotein expression in kainic acid-induced status epilepticus

1988 • 165 citations

Seizures induce dramatic and distinctly different changes in enkephalin, dynorphin, and CCK immunoreactivities in mouse hippocampal mossy fibers

1988 • 157 citations

Structure, chromosome location, and expression of the mouse zinc finger gene Krox-20: multiple gene products and coregulation with the proto-oncogene c-fos.

1989 • 155 citations

Transcription and Promoter Usage of the myc Gene tn Normal Somatic and Spermatogenic Cells

1984 • 150 citations

Proto-oncogene c-fos is transiently induced in the rat cerebral cortex after forebrain ischemia

1989 • 149 citations

Morphine activation of c-fos expression in rat brain

1988 • 147 citations

Selective induction of a heat shock gene in fibre tracts and cerebellar neurons of the rabbit brain detected by in situ hybridization

1987 • 145 citations

Expression of a homeo domain protein in noncontact-inhibited cultured cells and postmitotic neurons.

1987 • 143 citations

Chloride channels and their modulation by neurotransmitters and drugs.

1988 • 134 citations

Analysis of Fos protein complexes and Fos-related antigens by high-resolution two-dimensional gel electrophoresis.

1987 • 131 citations

Localization and induction of c-fos protein-like immunoreactive material in the nuclei of adult mammalian neurons

1988 • 129 citations

Increased resting and evoked release of transmitter following repetitive electrical tetanization in hippocampus: a biochemical correlate to long-lasting synaptic potentiation

1981 • 125 citations

L-DOPA activates c-fos in the striatum ipsilateral to a 6-hydroxydopamine lesion of the substantia nigra

1989 • 121 citations

Remodeling of synaptic architecture during hippocampal "kindling".

1988 • 118 citations

Electrical stimulation in vivo increases the expression of proenkephalin mRNA and decreases the expression of prodynorphin mRNA in rat hippocampal granule cells.

1988 • 117 citations

Priming of D1-dopamine receptor responses: long-lasting behavioral supersensitivity to a D1-dopamine agonist following repeated administration to neonatal 6-OHDA-lesioned rats

1989 • 116 citations

Changes in dynorphin, enkephalin and cholecystokinin content of hippocampus and substantia nigra after amygdala kindling

1986 • 113 citations

Barium modulates c-fos expression and post-translational modification.

1986 • 108 citations

Proto-oncogenes and differentiation

1986 • 108 citations

Novel Jun- and Fos-related proteins in Drosophila are functionally homologous to enhancer factor AP-1.

1988 • 103 citations

Proto-oncogene fos: a multifaceted gene

1986 • 101 citations

Activation of specific glutamate receptor subtypes increases c-fos proto-oncogene expression in primary cultures of neonatal rat cerebellar granule cells

1987 • 100 citations

Fos C-terminal mutations block down-regulation of c-fos transcription following serum stimulation.

1988 • 100 citations

Proto-oncogenes in the nervous system

1988 • 98 citations

Proto-oncogene c-myc is expressed in cerebellar neurons at different developmental stages.

1986 • 96 citations

High-frequency discharge of dentate granule cells, but not long-term potentiation, induces c-fos protein

1988 • 93 citations

Unusual Early Cretaceous birds from Spain

1988 • 87 citations

Ubiquitin gene expression in Dictyostelium is induced by heat and cold shock, cadmium, and inhibitors of protein synthesis

1988 • 83 citations

Presence of c-fos-like immunoreactivity in the adult rat brain

1987 • 82 citations

Amygdala kindling and c-fos protein(s)☆

1988 • 81 citations

Two adjacent promoter elements mediate nerve growth factor activation of the c-fos gene and bind distinct nuclear complexes.

1988 • 79 citations

Variations in c-fos gene expression during rat brain development

1988 • 77 citations

c-myc protein in normal tissue. Effects of fixation on its apparent subcellular distribution.

1988 • 77 citations

Autoradiographic localization of a calcium channel antagonist, [3H]nitrendipine, binding site in rat brain

1983 • 76 citations

Cancer genes: rare recombinants instead of activated oncogenes (a review).

1987 • 76 citations

Amygdaloid kindling increases enkephalin-like immunoreactivity but decreases dynorphin-A-like immunoreactivity in rat hippocampus

1986 • 74 citations

Proto-oncogene c-fos induction in rat hippocampus

1988 • 71 citations

Dissociation of c-fos from ODC expression and neuronal differentiation in a PC12 subline stably transfected with an inducible N-ras oncogene

1988 • 70 citations

Synthesis of Early RNA in Bacteriophage T4-infected Escherichia coli B

1969 • 69 citations

Fos‐Like Immunoreactivity Induced by Seizure in Mice Is Specifically Associated With Euchromatin in Neurons

1989 • 68 citations

β-Adrenergic Stimulation of c-fos Gene Expression in the Mouse Submandibular Gland

1986 • 66 citations

Interaction of calmodulin inhibitors and protein kinase C inhibitors with voltage-dependent calcium channels

1987 • 65 citations

Progress on LTP at hippocampal synapses: a post-synaptic Ca2+ trigger for memory storage?

1987 • 64 citations

Beta-adrenergic stimulation of c-fos gene expression in the mouse submandibular gland.

1986 • 54 citations

Prodynorphin gene expression in spinal cord is enhanced after traumatic injury in the rat

1988 • 53 citations

Tumor Promoter-Inducible Genes Are Differentially Expressed in the Developing Mouse

1988 • 53 citations

Effect of inhibitors of protein synthesis on the development of kindled seizures in rats

1979 • 51 citations

Effect of various calcium channel blockers on three different models of limbic seizures in rats

1988 • 50 citations

Proto-oncogene c-fos is highly induced by disruption of neonatal but not of mature brain tissue

1987 • 45 citations

The primary structure of the murine multifinger gene mKr2 and its specific expression in developing and adult neurons.

1988 • 45 citations

Kainic acid-induced seizures increase c-fos-like protein in the hippocampus

1988 • 44 citations

Tumor promoter-inducible genes are differentially expressed in the developing mouse.

1988 • 42 citations

Effects of protein synthesis inhibition on kindling in the mouse

1980 • 37 citations

Epileptic discharges induced by pentylenetetrazol: changes of shape of dendrites

1988 • 24 citations

Widespread distribution of the c-src gene product in nerve cells and axon terminals in the adult rat brain

1988 • 24 citations

New trends in mapping benzodiazepine receptors.

1988 • 18 citations

Molecular associations and conceptual connections

1988 • 17 citations

Postnatal development of a cellular response to stress in rat brain

1983 • 13 citations

Seizure-inducible c-fos protein(s) in mammalian neurons

1988 • 13 citations

Induction of ornithine decarboxylase in adult rat hippocampal slices

1988 • 11 citations

C-Fos mRNA induction under vitamin B6 antagonist-induced seizure

1989 • 10 citations

Oncogenes in neural tumors

1986 • 9 citations

The marriage of oncogenes and anti-oncogenes

1988 • 8 citations

Lemons and limes

1985 • 1 citations

Estrogens modulate c-fos and parvalbumin gene expression in the rat CNS

1988 • 1 citations

Deleted Work

1955 • 0 citations