Back to search

The role of cytochrome P450 2D6 in the metabolism of moclobemide

Data up to Jan 2025

Published1996
Citations23
References30

Total Citations Per Year

Abstract

References (30)

POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN

1977 • 1,196 citations

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

1988 • 717 citations

Polymorphic dextromethorphan metabolism: Co-segregation of oxidative O-demethylation with debrisoquin hydroxylation

1985 • 386 citations

MEDICAL NEMESIS

1974 • 377 citations

Human cytochromes P450: problems and prospects

1992 • 364 citations

The role of individual human cytochrpmes P450 in drug metabolism and clinical response

1992 • 246 citations

Neurochemical profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type A.

1989 • 195 citations

Human cytochrome P-450 enzymes

1992 • 157 citations

The role of CYP2D6 in primary and secondary oxidative metabolism of dextromethorphan: in vitro studies using human liver microsomes.

1994 • 101 citations

Moclobemide, a substrate of CYP2C19 and an inhibitor of CYP2C19, CYP2D6, and CYP1A2: A panel study*

1995 • 98 citations

Monoamine oxidase : basic and clinical aspects

1993 • 96 citations

The pharmacogenetics of the selective serotonin reuptake inhibitors

1993 • 90 citations

Amitriptyline metabolism: Relationship to polymorphic debrisoquine hydroxylation

1983 • 70 citations

Pharmacokinetics of dextromethorphan and dextrorphan: a single dose comparison of three preparations in human volunteers.

1987 • 68 citations

Biotransformation of moclobemide in humans

1990 • 66 citations

An update of recent moclobemide interaction data

1993 • 63 citations

Clinical Pharmacokinetics of the Monoamine Oxidase-A Inhibitor Moclobemide*

1995 • 62 citations

Interactions of moclobemide with concomitantly administered medication: evidence from pharmacological and clinical studies

1992 • 56 citations

Determination of the new monoamine oxidase inhibitor moclobemide and three of its metabolites in biological fluids by high-performance liquid chromatography

1987 • 51 citations

Inhibition of hepatic P-450 isoenzymes by serotonin selective reuptake inhibitors: in vitro and in vivo findings and their implications for patient care.

1994 • 50 citations

Clinical implications of genetic polymorphism in drug metabolism.

1994 • 50 citations

Clinical consequences of polymorphic drug oxidation

1991 • 34 citations

Relevance of genetic polymorphism in drug metabolism in the development of new drugs

1989 • 33 citations

Moclobemide treatment causes a substantial rise in the sparteine metabolic ratio. Danish University Antidepressant Group.

1993 • 30 citations

Debrisoquine oxidative phenotyping and psychiatric drug treatment

1989 • 28 citations

Influence of food on the tyramine pressor effect during chronic moclobemide treatment of healthy volunteers

1992 • 22 citations

Cimetidine alters the disposition kinetics of the monoamine oxidase-A inhibitor moclobemide

1991 • 20 citations

Role of cytochrome P4502D6 in the metabolism of brofaromine

1993 • 19 citations

Comparison of the pharmacokinetics of moclobemide in poor and efficient metabolizers of debrisoquine

1990 • 16 citations

Cytochromes in Psychopharmacology

1994 • 12 citations

Cited By (0)

Loading...
The role of cytochrome P450 2D6 in the metabolism of moclobemide (1996) – European Neuropsychopharmacology | Metascience Observatory Explorer