Regional Cerebral Blood Flow during and after 2 Hours of Middle Cerebral Artery Occlusion in the Rat

Thresholds in cerebral ischemia - the ischemic penumbra.

1981 • 2,780 citations

Temporal profile of neuronal damage in a model of transient forebrain ischemia

1982 • 2,695 citations

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

1986 • 2,584 citations

Pathophysiology and treatment of focal cerebral ischemia

1992 • 1,287 citations

Experimental studies of ischemic brain edema

1986 • 932 citations

Measurement of local cerebral blood flow with iodo [14C] antipyrine

1978 • 927 citations

Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons.

1991 • 741 citations

Insulin effects on monovalent cation transport and Na-K-ATPase activity

1978 • 692 citations

Correlation between cerebral blood flow and histologic changes in a new rat model of middle cerebral artery occlusion.

1989 • 516 citations

Influx of leukocytes and platelets in an evolving brain infarct (Wistar rat).

1994 • 491 citations

Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats.

1992 • 467 citations

Progress in Brain Research

1992 • 448 citations

George E. Brown memorial lecture. Oxygen radicals in cerebral vascular injury.

1985 • 393 citations

Postischemic administration of an anti-Mac-1 antibody reduces ischemic cell damage after transient middle cerebral artery occlusion in rats.

1994 • 347 citations

Anti–Intercellular Adhesion Molecule–1 Antibody Reduces Ischemic Cell Damage After Transient But Not Permanent Middle Cerebral Artery Occlusion in the Wistar Rat

1995 • 346 citations

Ischemic Thresholds of Cerebral Protein Synthesis and Energy State following Middle Cerebral Artery Occlusion in Rat

1991 • 337 citations

Oxygen radicals in cerebral ischemia

1992 • 332 citations

Temporal thresholds for neocortical infarction in rats subjected to reversible focal cerebral ischemia.

1991 • 325 citations

Ischemic penumbra in a model of reversible middle cerebral artery occlusion in the rat

1992 • 309 citations

Experimental studies of ischemic brain edema. 1. A new experimental model of cerebral embolism in rats in which recirculation can be introduced in the ischemic area

1986 • 294 citations

Pathophysiology of acute ischaemic stroke

1992 • 292 citations

Mechanisms of secondary brain injury.

1996 • 261 citations

Role of cell adhesion molecules in brain injury after transient middle cerebral artery occlusion in the rat

1994 • 257 citations

Differential regional vulnerability in transient focal cerebral ischemia.

1982 • 241 citations

N-tert-butyl-alpha-phenylnitrone improves recovery of brain energy state in rats following transient focal ischemia.

1995 • 233 citations

A new model of temporary focal neocortical ischemia in the rat.

1992 • 225 citations

Mechanisms of Secondary Brain Damage in Global and Focal Ischemia: A Speculative Synthesis

1995 • 208 citations

Glutamate‐Mediated Injury in Focal Cerebral Ischemia: The Excitotoxin Hypothesis Revised

1994 • 199 citations

Mechanisms of secondary brain injury

1996 • 197 citations

Local Cerebral Blood Flow in the Recovery Period following Complete Cerebral Ischemia in the Rat

1983 • 196 citations

Delayed treatment with the spin trap α‐phenyl‐N‐tert‐butyl nitrone (PBN) reduces infarct size following transient middle cerebral artery occlusion in rats

1994 • 196 citations

Microvascular changes during cerebral ischemia and reperfusion.

1994 • 194 citations

The cerebral ischemic penumbra.

1987 • 175 citations

Hyperthermia complicates middle cerebral artery occlusion induced by an intraluminal filament

1994 • 163 citations

Recirculation in the Rat Brain following Incomplete Ischemia

1983 • 159 citations

Selective Necrosis and Total Necrosis in Focal Cerebral Ischemia. Neuropathologic Observations on Experimental Middle Cerebral Artery Occlusion in the Macaque Monkey

1984 • 158 citations

Focal cerebral ischemia in the rat: Topography of hemodynamic and histopathological changes

1984 • 157 citations

Experimental evidence of ischemic thresholds and functional recovery.

1992 • 153 citations

Effect of Reperfusion Following Cerebral Ischaemia on the Activity of the Mitochondrial Respiratory Chain in the Gerbil Brain

1995 • 142 citations

Recirculation model following MCA occlusion in rats

1985 • 137 citations

Delayed Treatment with α-Phenyl-N-tert-butyl Nitrone (PBN) Attenuates Secondary Mitochondrial Dysfunction after Transient Focal Cerebral Ischemia in the Rat

1996 • 136 citations

Postischemic inhibition of cerebral cortex pyruvate dehydrogenase

1994 • 134 citations

The Calcium Content of Mitochondria from Brain Subregions Following Short‐Term Forebrain Ischemia and Recirculation in the Rat

1994 • 130 citations

Cerebrovascular Diseases

1988 • 114 citations

Blood-brain barrier disruption and exacerbation of ischemic brain edema after restoration of blood flow in experimental focal cerebral ischemia

1988 • 97 citations

The CBF Threshold and Dynamics for Focal Cerebral Infarction in Spontaneously Hypertensive Rats

1992 • 90 citations

Incomplete versus complete cerebral ischemia: Improved outcome with a minimal blood flow

1979 • 89 citations

Inflammatory reactions at the blood-endothelial interface in acute stroke.

1996 • 89 citations

Cerebral Blood Flow in Ischemia Caused by Carotid Artery Ligation in the Rat

1973 • 81 citations

Threshold relationship between cerebral blood flow, glucose utilization, and energy metabolites during development of stroke in gerbils

1992 • 70 citations

Secondary bioenergetic failure after transient focal ischaemia is due to mitochondrial injury

1996 • 65 citations

Influence of Nitrous Oxide on Local Cerebral Blood Flow in Awake, Minimally Restrained Rats

1981 • 55 citations

Local hemodynamic changes during transient middle cerebral artery occlusion and recirculation in the rat: a [14C]iodoantipyrine autoradiographic study

1995 • 49 citations

Effect of Indomethacin on Local Cerebral Blood Flow in Awake, Minimally Restrained Rats

1981 • 23 citations

Uncoupling of blood flow and glucose metabolism in the neighboring postischemic edematous brain area.

1990 • 10 citations