Insulin-Like Growth Factor Binding Proteins in the Nervous System

Analysis of serum insulin-like growth factor binding proteins using Western blotting: Use of the method for titration of the binding proteins and competitive binding studies

1986 • 1,158 citations

Differential expression of insulin-like growth factor genes in rat central nervous system.

1988 • 477 citations

Effects of insulin, insulin-like growth factor-II, and nerve growth factor on neurite formation and survival in cultured sympathetic and sensory neurons

1986 • 426 citations

Tissue Distribution of Insulin-Like Growth Factor I and II Messenger Ribonucleic Acid in the Adult Rat*

1987 • 418 citations

Insulin‐like growth factor I promotes cell proliferation and oligodendroglial commitment in rat glial progenitor cells developing in vitro

1988 • 361 citations

Insulin-Like Growth Factors: A Role in Growth Hormone Negative Feedback and Body Weight Regulation via Brain

1983 • 354 citations

Insulin-Like Growth Factor I (IGF-I)-Binding Protein Complex Is a Better Mitogen than Free IGF-I*

1989 • 318 citations

Brain neurons develop in a serum and glial free environment: effects of transferrin, insulin- insulin-like growth factor-I and thyroid hormone on neuronal survival, growth and differentiation

1987 • 249 citations

Cloning, characterization, and expression of a human insulin-like growth factor binding protein

1988 • 249 citations

Insulin growth factors regulate the mitotic cycle in cultured rat sympathetic neuroblasts.

1988 • 239 citations

Characterization of the Acid-Labile Subunit of the Growth Hormone-Dependent Insulin-Like Growth Factor Binding Protein Complex*

1988 • 239 citations

Insulin-Like Growth Factor (IGF) and IGF-Binding Proteins: Comparison of Human Serum and Lymph*

1988 • 216 citations

Insulin-like growth factor II (IGF II) in human brain: regional distribution of IGF II and of higher molecular mass forms.

1985 • 205 citations

Insulin-like growth factor I receptors in neuronal and glial cells. Characterization and biological effects in primary culture.

1987 • 190 citations

Insulin and insulin-like growth factor II permit nerve growth factor binding and the neurite formation response in cultured human neuroblastoma cells.

1984 • 168 citations

Insulin-like growth factor (IGF-1) as a stimulator of regeneration in the freeze-injured rat sciatic nerve

1989 • 167 citations

Characterization of somatomedins from human fetal brain: identification of a variant form of insulin-like growth factor I.

1986 • 166 citations

Different Tissue Distribution and Hormonal Regulation of Messenger RNAs Encoding Rat Insulin-Like Growth Factor-Binding Proteins-1 and -2

1990 • 165 citations

A Low Molecular Weight Insulin-Like Growth Factor Binding Protein from Rat: cDNA Cloning and Tissue Distribution of its Messenger RNA

1989 • 158 citations

Insulin‐like growth factor (IGF) binding to human fibroblast and glioblastoma cells: The modulating effect of cell released IGF binding proteins (IGFBPs)

1990 • 143 citations

Relationship of insulin-like growth factor II gene expression in muscle to synaptogenesis.

1989 • 143 citations

Insulin-like growth factor I in cultured rat astrocytes: expression of the gene, and receptor tyrosine kinase.

1987 • 141 citations

The 25-KiloDalton Insulin-Like Growth Factor (IGF)-Binding Protein Inhibits both Basal and IGF-I-Mediated Growth of Chick Embryo Pelvic Cartilagein Vitro

1990 • 136 citations

Characterization of a neuronal subtype of insulin-like growth factor I receptor.

1987 • 132 citations

Production of insulin‐like growth factors and their carrier by rat pituitary gland and brain explants in culture

1981 • 132 citations

Complementary DNA structure of the high molecular weight rat insulin-like growth factor binding protein (IGF-BP3) and tissue distribution of its mRNA

1989 • 125 citations

Identification and Characterization of a Rat Decidual Insulin-Like Growth Factor-Binding Protein Complementary DNA

1990 • 124 citations

Identification of an insulin‐like growth factor‐binding protein in human cerebrospinal fluid with a selective affinity for IGF‐II

1986 • 118 citations

Isolation from human cerebrospinal fluid of a new insulin‐like growth factor‐binding protein with a selective affinity for IGF‐II

1989 • 116 citations

Characterization of Insulin-Like Growth Factor Binding Proteins Produced in the Rat Central Nervous System*

1990 • 115 citations

Human Preovulatory Follicular Fluid, Luteinized Cells of Hyperstimulated Preovulatory Follicles, and Corpus Luteum Contain Placental Protein 12*

1984 • 114 citations

Rapid axoplasmic transport of insulin-like growth factor I in the sciatic nerve of adult rats

1987 • 113 citations

Ontogeny of Serum Insulin-Like Growth Factor Binding Proteins in the Rat*

1989 • 106 citations

Histochemical localization of IGF-I and IGF-II mRNA in the rat between birth and adulthood

1988 • 102 citations

A comparison of the biological activity of the recombinant intact and truncated insulin-like growth factor 1 (IGF-1)

1989 • 101 citations

The Expression Pattern of an Insulin-Like Growth Factor (IGF)-Binding Protein Gene Is Distinct from IGF-II in the Midgestational Rat Embryo

1990 • 100 citations

The Fetal Rat Binding Protein for Insulin-Like Growth Factors is Expressed in the Choroid Plexus and Cerebrospinal Fluid of Adult Rats

1989 • 94 citations

Immunological distribution of one form of insulin-like growth factor (IGF)-binding protein and IGF peptides in human fetal tissues

1989 • 88 citations

The Insulin-Like Growth Factor I Content in Human Milk Increases Between Early and Full Lactation*

1988 • 71 citations

A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide

1989 • 70 citations

Rat astroglial somatomedin/insulin-like growth factor binding proteins: characterization and evidence of biologic function

1988 • 70 citations

Inhibitors of Glucose Uptake Stimulate the Production of Insulin-Like Growth Factor-Binding Protein (IGFBP-1) by Human Fetal Liver*

1990 • 68 citations

Regulation of Insulin-Like Growth Factor (IGF)-Binding Protein Synthesis by Insulin and IGF-I in Cultured Bovine Fibroblasts*

1990 • 67 citations

Structural and Immunological Comparison of Insulin-Like Growth Factor Binding Proteins of Cerebrospinal and Amniotic Fluids*

1989 • 63 citations

Insulin-Like Growth Factor-Binding Proteins from Vascular Endothelial Cells: Purification, Characterization, and Intrinsic Biological Activities*

1989 • 62 citations

The Binding Characteristics and Biological Effects in FRTL5 Cells of Placental Protein-12, an Insulin-Like Growth Factor-Binding Protein Purified from Human Amniotic Fluid*

1989 • 59 citations

Expression of the BRL-3A Insulin-like Growth Factor Binding Protein (rBP-30) in the Rat Central Nervous System

1989 • 59 citations

IDENTIFICATION OF INSULIN-UKE GROWTH FACTOR-BINDING PROTEIN-2 (IGF-BP-2) AND A LOW MOLECULAR WEIGHT IGF-BP IN HUMAN SEMINAL PLASMA

1990 • 56 citations

Insulin, Insulin-like Growth Factors, and Their Receptors in the Central Nervous System

1987 • 55 citations

Evidence for the role of insulin-like growth factor II (IGF-II) in the control of food intake

1987 • 51 citations

Purified Preparations of the Amniotic Fluid-Derived Insulin-Like Growth Factor-Binding Protein Contain Multimeric Forms that Are Biologically Active*

1989 • 51 citations

Molecular and cellular biology of insulin-like growth factors and their receptors

1991 • 48 citations

Characterization of insulin-like growth factor binding proteins of cultured rat astroglial and neuronal cells

1989 • 42 citations

Expression of insulin and insulin-like growth factor receptors and binding proteins by retinal pigment epithelium

1991 • 39 citations

Identification of Rat Cell Lines that Preferentially Express Insulin-Like Growth Factor Binding Proteins rlGFBP-1, 2, or 3

1990 • 39 citations

Insulin-Like Growth Factor Receptors and Binding Protein in Rat Neuroblastoma Cells*

1989 • 37 citations

Characterization of Insulin-Like Growth Factor-Binding Proteins in Cultured Rat Pituitary Cells*

1989 • 30 citations

The 34 kilodalton insulin-like growth factor binding proteins in human cerebrospinal fluid and the A673 rhabdomyosarcoma cell line are human homologues of the rat BRL-3A binding protein

1989 • 26 citations

Characterization of Insulin-like Growth Factor II Peptides Secreted by Explants of Neonatal Brain and of Adult Pituitary from Rats*

1988 • 17 citations

Insulin-Like Growth Factors and Their Receptors in the Pituitary and Hypothalamus

1987 • 9 citations

On the nomenclature of the insulin-like growth factor binding proteins

1989 • 8 citations

Molecular and Cellular Biology of Insulin-like Growth Factors and their Receptors. Edited by D. LeRoith & M. K. Raizada.

1990 • 1 citations