Insulin-Like Growth Factor Receptors and Binding Protein in Rat Neuroblastoma Cells*

THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY

1963 • 10,322 citations

Growth of a rat neuroblastoma cell line in serum-free supplemented medium.

1979 • 2,285 citations

Clonal cell lines from the rat central nervous system

1974 • 727 citations

An insulin-like growth factor (IGF) binding protein enhances the biologic response to IGF-I.

1987 • 682 citations

The Somatomedins: A Family of Insulinlike Hormones under Growth Hormone Control

1974 • 281 citations

Demonstration of Specific Plasma Protein Binding Sites For Somatomedin

1977 • 272 citations

Brain neurons develop in a serum and glial free environment: effects of transferrin, insulin- insulin-like growth factor-I and thyroid hormone on neuronal survival, growth and differentiation

1987 • 249 citations

Characterization of Insulin-Like Growth Factor Receptors in Rat Anterior Pituitary, Hypothalamus, and Brain*

1984 • 199 citations

Insulin and insulin-like growth factor II permit nerve growth factor binding and the neurite formation response in cultured human neuroblastoma cells.

1984 • 168 citations

Evidence for the presence of specific receptors for insulin-like growth factors 1 (IGF-1) and 2 (IGF-2) and insulin throughout the adult human brain

1982 • 166 citations

Two types of receptor for insulin-like growth factors in mammalian brain.

1985 • 163 citations

EVIDENCE FOR TWO SPECIES OF INSULIN-LIKE GROWTH FACTOR II (IGF II AND “BIG” IGF II) IN HUMAN SPINAL FLUID

1982 • 158 citations

Specific binding of a somatomedin-like polypeptide in rat serum depends on growth hormone

1976 • 146 citations

Characterization of a neuronal subtype of insulin-like growth factor I receptor.

1987 • 132 citations

Characterization of High Affinity Receptors for Insulin-Like Growth Factors I and II on Rat Anterior Pituitary Cells*

1984 • 128 citations

Plasma Somatomedin-Binding Proteins in Hypopituitarism: Changes during Growth Hormone Therapy*

1981 • 123 citations

Ontogeny of Receptors for Insulin-Like Peptides in Chick Embryo Tissues: Early Dominance of Insulin-Like Growth Factor over Insulin Receptors in Brain*

1985 • 116 citations

Affinity-labeled plasma somatomedin-C/insulinlike growth factor I binding proteins. Evidence of growth hormone dependence and subunit structure.

1985 • 113 citations

Demonstration of insulin-like growth factor (IGF-I and -II) receptors and binding protein in human breast cancer cell lines

1988 • 110 citations

Purification and amino-terminal sequence of an insulin-like growth factor-binding protein secreted by rat liver BRL-3A cells.

1986 • 108 citations

Characterization of somatomedin/insulin-like growth factor receptors and correlation with biologic action in cultured neonatal rat astroglial cells

1987 • 107 citations

The Growth Hormone Dependence of a Somatomedin-Binding Protein in Human Serum*

1981 • 101 citations

Structural and Immunohistochemical Characterization of Insulin-Like Growth Factor I and II Receptors in the Murine Central Nervous System*

1988 • 84 citations

Mitogenic response of human SH-SY5Y neuroblastoma cells to insulin-like growth factor I and II is dependent on the stage of differentiation.

1986 • 78 citations

Insulin and Insulin-Like Growth Factor (Somatomedin) Receptors on Cloned Rat Pituitary Tumor Cells*

1985 • 78 citations

Affinity-Labeled Somatomedin-C Receptors and Binding Proteins from the Human Fetus*

1984 • 62 citations

Somatomedin levels in cerebrospinal fluid from adults with pituitary disorders

1984 • 58 citations

Distribution of Insulin-Like Growth Factor II Receptor Immunoreactivity in Rat Tissues*

1988 • 49 citations

Somatomedin-C/Insulin-Like Growth Factor I-Binding Proteins in Human Amniotic Fluid and in Fetal and Postnatal Blood: Evidence of Immunological Homology*

1985 • 48 citations

Alterations in the Synthesis of a Fibroblast Surface Associated 35 K Protein Modulates the Binding of Somatomedin-C/lnsulin-Like Growth Factor I*

1987 • 46 citations

Method for purification of an insulin-like growth factor-binding protein produced by human HEP G2 hepatoma cells

1987 • 42 citations

Elevated concentration of IGF II in brain tissue from an infant with macrencephaly

1986 • 41 citations

Purification of the Insulin-like growth factor II (IGF-II) receptor from an IGF-II-producing cell line, and generation of an antibody which both immunoprecipitates and blocks the type 2 IGF receptor

1986 • 40 citations

Enhancement of insulin-like growth factor 2 receptors in glioblastoma

1986 • 34 citations

Structural and Functional Characteristics of Insulin Receptors in Rat Neuroblastoma Cells

1985 • 31 citations

Putative neurotransmitters in clonal cell lines

1975 • 30 citations

Identification of receptors for insulin-like growth factor II in two insulin-like growth factor II producing cell lines

1986 • 24 citations

The Insulin-Like Growth Factor-II (IGF II) Receptor from Rat Brain Is of Lower Apparent Molecular Weight than the IGF II Receptor from Rat Liver*

1987 • 20 citations

Synthetic insulin-like growth factor II

1985 • 18 citations