Neurotoxicity and dysfunction of dopaminergic systems associated with AIDS dementia

The AIDS dementia complex: II. Neuropathology

1986 • 1,280 citations

Striatal dopamine nerve terminal markers in human, chronic methamphetamine users

1996 • 715 citations

Drug dependence: stress and dysregulation of brain reward pathways

1998 • 652 citations

Biochemical aspects of Parkinson's disease

1998 • 532 citations

Dendritic injury is a pathological substrate for human immunodeficiency virus—related cognitive disorders

1997 • 470 citations

HIV-1 Protein Tat Induces Apoptosis of Hippocampal Neurons by a Mechanism Involving Caspase Activation, Calcium Overload, and Oxidative Stress

1998 • 400 citations

Evidence for Synaptic Apoptosis

1998 • 342 citations

Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic

1996 • 310 citations

Cortical Synaptic Density is Reduced in Mild to Moderate Human Immunodeficiency Virus Neurocognitive Disorder

1999 • 289 citations

Human immunodeficiency virus type 1 tat activates non—N‐methyl‐<scp>D</scp>‐aspartate excitatory amino acid receptors and causes neurotoxicity

1995 • 277 citations

Under Siege: The Brain on Opiates

1996 • 263 citations

Amyloid β-peptide induces apoptosis-related events in synapses and dendrites

1998 • 254 citations

Neurobiological aspects of human immunodeficiency virus infection:Neurotoxic mechanisms

1998 • 231 citations

Cortical dendritic pathology in human immunodeficiency virus encephalitis.

1992 • 194 citations

Striatal dopamine, dopamine transporter, and vesicular monoamine transporter in chronic cocaine users

1996 • 168 citations

Opiates as potential cofactors in progression of HIV-1 infections to AIDS

1998 • 158 citations

Opioid receptor-mediated inhibition of dopamine and acetylcholine release from slices of rat nucleus accumbens, olfactory tubercle and frontal cortex

1990 • 157 citations

Intraventricular Injection of Human Immunodeficiency Virus Type 1 (HIV-1) Tat Protein Causes Inflammation, Gliosis, Apoptosis, and Ventricular Enlargement

1998 • 153 citations

Extrapyramidal symptoms due to dopamine-blocking agents in patients with AIDS encephalopathy

1991 • 148 citations

Cerebrospinal fluid dopamine in HIV-1 infection

1994 • 147 citations

HIV Dementia and the Basal Ganglia

1997 • 125 citations

Dopamine deficits in the brain

1996 • 123 citations

HIV Infection of Human Choroid Plexus

1995 • 115 citations

Neurotoxicity of peptide analogues of the transactivating protein tat from maedi-visna virus and human immunodeficiency virus

1993 • 111 citations

Exogenous tat protein activates central nervous system-derived endothelial cells

1994 • 96 citations

HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures

1995 • 95 citations

Prostate Apoptosis Response‐4 Production in Synaptic Compartments Following Apoptotic and Excitotoxic Insults

1999 • 94 citations

Polymorphisms of the dopamine D 4 receptor and response to antipsychotic drugs

1999 • 81 citations

Sodium Valproate, an Anticonvulsant Drug, Stimulates Human Immunodeficiency Virus Type 1 Replication Independently of Glutathione Levels

1996 • 78 citations

HIV-1 Proviral DNA Load Across Neuroanatomic Regions of Individuals With Evidence for HIV-1-Associated Dementia

1997 • 75 citations

Cerebrospinal fluid catecholamine metabolites in HIV‐infected patients

1991 • 71 citations

Evidence that Par-4 Participates in the Pathogenesis of HIV Encephalitis

1999 • 69 citations

Pilot study with clozapine in patients with HIV-associated psychosis and drug-induced parkinsonism

1999 • 63 citations

Neuropathogenesis of Chimeric Simian/Human Immunodeficiency Virus infection In Pig-tailed and Rhesus Macaques

1997 • 55 citations

Regulation of glutathione and cell toxicity following exposure to neurotropic substances and human immunodeficiency virus-1in vitro

1997 • 45 citations

Cell Type-Dependent Effect of Sodium Valproate on Human Immunodeficiency Virus Type 1 Replicationin Vitro

1997 • 43 citations

Valpoic acid reduces the intracellular level of glutathione and stimulates human immunodeficiency virus

1994 • 40 citations

Levodopa therapy improves motor function in HIV-infected children with extrapyramidal syndromes

1996 • 39 citations

Opioids Disrupt Ca2+Homeostasis and Induce Carbonyl Oxyradical Production in Mouse Astrocytesin Vitro:Transient Increases and Adaptation to Sustained Exposure

1998 • 38 citations

Tryptophan Concentrations Increase in Cerebrospinal Fluid and Blood after Zidovudine Treatment in Patients with HIV Type 1 Infection

1994 • 38 citations

Monoamine metabolite levels in CSF of SIV-infected rhesus monkeys (Macaca mulatta)

1997 • 30 citations

Metabolites of the antipsychotic agent clozapine inhibit the replication of human immunodeficiency virus type 1

1997 • 30 citations

Electrophysiological evidence for a reciprocal interaction between amphetamine and cocaine‐related drugs on rat midbrain dopaminergic neurons

1999 • 21 citations

Inhibition of human immunodeficiency virus type 1 replication and cytopathicity by synthetic soluble catecholamine melanins in vitro

1990 • 19 citations

Increased dopamine receptor sensitivity in the rat following acute administration of sufentanil, U50,488H and d-Ala2-d-Leu5-enkephalin

1991 • 18 citations

Intermittent morphine administration induces a long-lasting synergistic effect of corticosterone on dopamine D1 receptor functioning in rat striatal GABA neurons

1997 • 18 citations

High signal intensity of both putamina in patients with HIV infection

1991 • 12 citations