Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

Cellular uptake of the tat protein from human immunodeficiency virus

1988 • 2,690 citations

Detection of AIDS Virus in Macrophages in Brain Tissue from AIDS Patients with Encephalopathy

1986 • 1,694 citations

Calcium Signaling in Neurons: Molecular Mechanisms and Cellular Consequences

1995 • 1,421 citations

The AIDS Dementia Complex

1988 • 1,387 citations

The AIDS dementia complex: II. Neuropathology

1986 • 1,280 citations

Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients.

1986 • 1,242 citations

Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation

1993 • 805 citations

Dementia in AIDS patients

1993 • 671 citations

HIV‐1 infection of subcortical astrocytes in the pediatric central nervous system

1994 • 402 citations

The Acquired Immunodeficiency Syndrome Dementia Complex as the Presenting or Sole Manifestation of Human Immunodeficiency Virus Infection

1987 • 375 citations

Overexpression of nef as a marker for restricted HIV‐1 infection of astrocytes in postmortem pediatric central nervous tissues

1994 • 365 citations

The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence.

1993 • 355 citations

Inhibition of Antigen-Induced Lymphocyte Proliferation by Tat Protein from HIV-1

1989 • 338 citations

Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1

1991 • 305 citations

Cell surface receptors for extracellular matrix components

1990 • 297 citations

Abundant expression of HIV Nef and Rev proteins in brain astrocytes in vivo is associated with dementia

1995 • 281 citations

Human immunodeficiency virus type 1 tat activates non—N‐methyl‐<scp>D</scp>‐aspartate excitatory amino acid receptors and causes neurotoxicity

1995 • 277 citations

A novel integrin specificity exemplified by binding of the alpha v beta 5 integrin to the basic domain of the HIV Tat protein and vitronectin.

1993 • 264 citations

Epidemiology of human immunodeficiency virus encephalopathy in the United States

1992 • 245 citations

Pathology of HIV-1 Infection of the Central Nervous System. A review

1992 • 244 citations

The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes.

1993 • 230 citations

Repression of MHC Class I Gene Promoter Activity by Two-Exon Tat of HIV

1993 • 223 citations

Structural studies of HIV-1 tat protein

1995 • 191 citations

Cellular localization of an HIV-1 antigen in subacute AIDS encephalitis using an improved double-labeling immunohistochemical method.

1990 • 188 citations

Human immunodeficiency virus type 1–infected monocytic cells can destroy human neural cells after cell‐to‐cell adhesion

1992 • 166 citations

Are Ca2+-permeable kainate/AMPA receptors more abundant in immature brain?

1992 • 162 citations

Neurotoxicity of peptide analogues of the transactivating protein tat from maedi-visna virus and human immunodeficiency virus

1993 • 111 citations

HIV-1 Nef protein exhibits structural and functional similarity to scorpion peptides interacting with K+ channels

1991 • 95 citations

Low levels of human immunodeficiency virus replication in the brain tissue of children with severe acquired immunodeficiency syndrome encephalopathy.

1992 • 86 citations

Neurotoxicity of the human immunodeficiency virus type 1 Tat transactivator to PC12 cells requires the Tat amino acid 49‐58 basic domain

1995 • 70 citations

Identification of a novel cell attachment domain in the HIV-1 Tat protein and its 90-kDa cell surface binding protein.

1993 • 69 citations

HIV-1 Tat Alters Normal Organization of Neurons and Astrocytes in Primary Rodent Brain Cell Cultures: RGD Sequence Dependence

1993 • 66 citations

Lethal neurotoxicity in mice of the basic domains of HIV and SIV Rev proteins Study of these regions by circular dichroism

1991 • 50 citations

Activity of synthetic tat peptides in human immunodeficiency virus type 1 long terminal repeat-promoted transcription in a cell-free system.

1990 • 37 citations

Epitopes of human immunodeficiency virus regulatory proteins tat, nef, and rev are expressed in normal human tissue.

1992 • 34 citations

Equine infectious anemia virus Tat is a predominantly helical protein

1993 • 24 citations

Lymphocyte Emperipolesis in Human Glial Cells

1993 • 20 citations