Differential effects of mepacrine, chloroquine and hydroxychloroquine on superoxide anion generation, phospholipid methylation and arachidonic acid release by human blood monocytes

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Phospholipid Methylation and Biological Signal Transmission

1980 • 1,101 citations

Calcium messenger system: an integrated view.

1984 • 916 citations

Interaction of drugs with calmodulin

1982 • 306 citations

Yeast Mannans inhibit binding and phagocytosis of zymosan by mouse peritoneal macrophages

1983 • 250 citations

Discontinuous density gradient separation of human minonuclear leucocytes using percoll® as gradient medium

1979 • 209 citations

Fluoride-mediated activation of the respiratory burst in human neutrophils. A reversible process.

1979 • 170 citations

Inhibition of lysosomal phospholipase A and phospholipase C by chloroquine and 4,4'-bis(diethylaminoethoxy) alpha, beta-diethyldiphenylethane.

1980 • 169 citations

Immunosuppressive potential of antimalarials

1983 • 158 citations

Pharmacologic actions of 4-aminoquinoline compounds

1983 • 146 citations

A rapid, isocratic method for phospholipid separation by high-performance liquid chromatography.

1983 • 116 citations

Changes in phosphatidylinositol and phosphatidic acid in stimulated human neutrophils

1983 • 101 citations

Activation of phospholipid methyltransferase by glucagon in rat hepatocytes.

1980 • 86 citations

Size distribution, electronic recognition, and counting of human blood monocytes

1976 • 67 citations

Transmethylation reactions regulate affinity and functional activity of chemotactic factor receptors on macrophages

1982 • 62 citations

Size distribution, electronic recognition, and counting of human blood monocytes

1976 • 56 citations

Oxidation of n-formyl methionyl chemotactic peptide by human neutrophils.

1981 • 50 citations

A possible metabolic explanation for drug-induced phospholipidosis

1976 • 46 citations

Inhibition of macrophage phagocytosis by methylation inhibitors. Lack of correlation of protein carboxymethylation and phospholipid methylation with phagocytosis.

1985 • 39 citations

Activation of murine macrophage cell lines. Possible involvement of protein kinases in stimulation of superoxide production.

1984 • 38 citations

Adrenocorticotropic stimulation and insulin inhibition of adipocyte phospholipid methylation.

1985 • 25 citations

Activation of the oxidative burst in human monocytes is associated with inhibition of methionine-dependent methylation of neutral lipids and phospholipids.

1984 • 23 citations

Estimation of plasma hydroxychloroquine by high-performance liquid chromatography with ultraviolet detection

1985 • 23 citations

Role of transmethylation in the elicitation of an oxidative burst in macrophages

1982 • 18 citations

Future directions

1981 • 17 citations

Pharmacogenetic studies on the drug‐related lupus syndrome. differences in antinuclear antibody development and drug‐induced DNA damage in rapid and slow acetylator animal models

1981 • 16 citations