Regulation of transmitter release at the squid giant synapse by presynaptic delayed rectifier potassium current.

A quantitative description of membrane current and its application to conduction and excitation in nerve

1952 • 21,965 citations

The effect of sodium ions on the electrical activity of the giant axon of the squid

1949 • 3,479 citations

POTENTIAL, IMPEDANCE, AND RECTIFICATION IN MEMBRANES

1943 • 2,733 citations

Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo

1952 • 2,384 citations

Molecular Biology of Learning: Modulation of Transmitter Release

1982 • 1,534 citations

The influence of potassium and chloride ions on the membrane potential of single muscle fibres

1959 • 1,458 citations

Co‐operative action of calcium ions in transmitter release at the neuromuscular junction

1967 • 1,326 citations

Sodium and calcium channels in bovine chromaffin cells

1982 • 983 citations

A study of synaptic transmission in the absence of nerve impulses

1967 • 888 citations

Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain.

1989 • 765 citations

The after‐effects of impulses in the giant nerve fibres of Loligo

1956 • 748 citations

Relationship between presynaptic calcium current and postsynaptic potential in squid giant synapse

1981 • 704 citations

Conduction and selectivity in potassium channels

1983 • 665 citations

Compartmentalization of the submembrane calcium activity during calcium influx and its significance in transmitter release

1985 • 609 citations

Negative Conductance Caused by Entry of Sodium and Cesium Ions into the Potassium Channels of Squid Axons

1972 • 554 citations

Anomalous Rectification in the Squid Giant Axon Injected with Tetraethylammonium Chloride

1965 • 439 citations

Aminopyridines and synaptic transmission

1980 • 404 citations

Presynaptic calcium currents in squid giant synapse

1981 • 366 citations

Calcium domains associated with individual channels can account for anomalous voltage relations of CA-dependent responses

1984 • 324 citations

DEMONSTRATION OF TWO STABLE POTENTIAL STATES IN THE SQUID GIANT AXON UNDER TETRAETHYLAMMONIUM CHLORIDE

1957 • 323 citations

Are the presynaptic membrane particles the calcium channels?

1981 • 318 citations

Calcium entry and transmitter release at voltage‐clamped nerve terminals of squid.

1985 • 314 citations

Potassium channels in cultured bovine adrenal chromaffin cells.

1985 • 313 citations

Dynamics of aminopyridine block of potassium channels in squid axon membrane.

1976 • 297 citations

Role of presynaptic calcium ions and channels in synaptic facilitation and depression at the squid giant synapse.

1982 • 291 citations

Presynaptic currents in mouse motor endings

1982 • 261 citations

Two Mutations of synaptic transmission in Drosophila

1977 • 246 citations

K+ channels close more slowly in the presence of external K+ and Rb+

1981 • 245 citations

Calcium dependence of presynaptic calcium current and post‐synaptic response at the squid giant synapse.

1986 • 218 citations

The mode of action of 4-aminopyridine and guanidine on transmitter release from motor nerve terminals

1977 • 215 citations

The effect of internal and external 4‐aminopyridine on the potassium currents in intracellularly perfused squid giant axons

1977 • 212 citations

Relationship between transmitter release and presynaptic calcium influx when calcium enters through discrete channels.

1986 • 207 citations

Effects of 4-aminopyridine on potassium currents in a molluscan neuron.

1981 • 204 citations

The action of calcium on neuronal synapses in the squid

1966 • 204 citations

Transmission by presynaptic spike-like depolarization in the squid giant synapse.

1982 • 203 citations

Slow changes in potassium permeability in skeletal muscle

1970 • 200 citations

3,4-diaminopyridine. A potent new potassium channel blocker

1978 • 183 citations

Optical recording of action potentials from vertebrate nerve terminals using potentiometric probes provides evidence for sodium and calcium components

1983 • 165 citations

Synaptic transmission in squid giant synapse after potassium conductance blockage with external 3- and 4-aminopyridine

1976 • 155 citations

The biophysical pharmacology of calcium-dependent acetylcholine secretion.

1985 • 149 citations

Slow Changes of Potassium Permeability in the Squid Giant Axon

1966 • 141 citations

Modification of transmitter release by ions which prolong the presynaptic action potential

1970 • 135 citations

Potassium ion accumulation in a periaxonal space and its effect on the measurement of membrane potassium ion conductance

1973 • 133 citations

The Inhibitory Effects of Omega‐Conotoxins on Ca Channels and Synapses^a

1989 • 125 citations

Calcium entry into voltage‐clamped presynaptic terminals of squid.

1985 • 123 citations

Divalent cations differentially support transmitter release at the squid giant synapse.

1984 • 119 citations

Action-potential duration and the modulation of transmitter release from the sensory neurons of Aplysia in presynaptic facilitation and behavioral sensitization

1986 • 118 citations

Intraterminal recordings from the rat neurohypophysis in vitro.

1990 • 115 citations

On numerical integration of the Hodgkin and Huxley equations for a membrane action potential

1974 • 112 citations

Effects of 4-aminopyridine on calcium action potentials and calcium current under voltage clamp in spinal neurons

1983 • 109 citations

Modulation of transmission at an inhibitory synapse in the central nervous system of the leech.

1978 • 108 citations

Identification of ionic currents at presynaptic nerve endings of the lizard.

1989 • 100 citations

Voltage-dependent K+ currents and underlying single K+ channels in pheochromocytoma cells.

1988 • 98 citations

Potassium channels in isolated presynaptic nerve terminals from rat brain.

1985 • 86 citations

Synaptic transmission mediated by single club endings on the goldfish Mauthner cell. II. Plasticity of excitatory postsynaptic potentials

1988 • 74 citations

Potassium conductance of the squid giant axon. Single-channel studies.

1988 • 73 citations

Synaptic transmission and effects of temperature at the squid giant synapse

1976 • 71 citations

Extracellular potassium and trasmitter release at the giant synapse of squid.

1977 • 64 citations

Single channels and ionic currents in peptidergic nerve terminals

1986 • 54 citations

Facilitation of transmitter release at squid synapses.

1978 • 54 citations

Potassium concentration changes in the transverse tubules of vertebrate skeletal muscle.

1980 • 52 citations

Phosphorylation modulates potassium conductance and gating current of perfused giant axons of squid.

1990 • 47 citations

Analysis of the action of 4-aminopyridine during repetitive stimulation at the neuromuscular junction

1979 • 44 citations

Simultaneous changes in the equilibrium potential and potassium conductance in voltage clamped Ranvier node in the frog.

1981 • 44 citations

The kinetics of recovery and development of potassium channel inactivation in perfused squid (Loligo pealei) giant axons.

1984 • 42 citations

Modulation of K channels in dialyzed squid axons. ATP-mediated phosphorylation.

1989 • 33 citations

Equilibrium Potential for the Postsynaptic Response in the Squid Giant Synapse

1974 • 33 citations

Adaptation in the input‐output relation of the synapse made by the barnacle's photoreceptor.

1985 • 28 citations

Tetraethylammonium Ions: Effect of Presynaptic Injection on Synaptic Transmission

1967 • 27 citations

Evidence for nonsynaptic neuronal interaction

1978 • 25 citations

Periaxonal K+ regulation in the small squid Alloteuthis. Studies on isolated and in situ axons

1988 • 24 citations

Effect of 4-aminopyridine on nerve terminal action potentials.

1981 • 21 citations

Axon voltage-clamp simulations. III. Postsynaptic region

1975 • 16 citations

Properties of tetraethylammonium ion-resistant K+ channels in the photoreceptor membrane of the giant barnacle.

1981 • 16 citations

Restricted diffusion of extracellular potassium at the neuromuscular junction of aged rats

1982 • 13 citations

Calcium-Dependent 4-aminopyridine stimulation of protein phosphorylation in squid optic lobe synaptosomes

1983 • 10 citations

Spatial control of membrane potential: a method for improved voltage clamping of the squid giant synapse

1988 • 4 citations

The voltage-dependence of transmitter release.

1986 • 2 citations