Stereochemical aspects of the metabolism of phenprocoumon in rat liver microsomes

Statistical methods

1967 • 19,533 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

A new carboxylation reaction. The vitamin K-dependent incorporation of H-14-CO3- into prothrombin.

1975 • 271 citations

Vitamin K-dependent carboxylase. Requirements of the rat liver microsomal enzyme system.

1976 • 172 citations

The Purification and Properties of an Abnormal Prothrombin Protein Produced by Dicumarol-treated Cows

1972 • 141 citations

A new vitamin K-dependent protein. A phospholipid-binding zymogen of a serine esterase.

1976 • 134 citations

Regioselective and stereoselective hydroxylation of R and S warfarin by different forms of purified cytochrome P-450 from rabbit liver

1978 • 76 citations

Warfarin—stereochemical aspects of its metabolism by rat liver microsomes

1976 • 58 citations

Enzymic hydroxylation of aromatic compounds

1961 • 55 citations

Synthesis and thin-layer chromatographic, ultraviolet, and mass spectral properties of the anticoagulant phenprocoumon and its monohydroxylated derivatives

1975 • 48 citations

Cumene hydroperoxide-supported microsomal hydroxylations of warfarin—A probe of cytochrome P-450 multiplicity and specificity

1979 • 39 citations

Stereochemical biotransformation of warfarin as a probe of the homogeneity and mechanism of microsomal hydroxylases

1977 • 33 citations

Metabolism in vitro of warfarin by enzymic and nonenzymic systems

1968 • 29 citations

Biotransformation of phenprocoumon in the rat

1975 • 24 citations

High-performance liquid and thin-layer chromatography of coumarin anti-coagulants and their degradation products

1976 • 23 citations

The synthesis of C-2 isotopically labeled optically pure warfarin and phenprocoumon

1980 • 11 citations

Anticoagulant Therapy

1964 • 8 citations

A specific and sensitive method for the determination of the anticoagulant phenprocoumon in plasma

1979 • 7 citations

[Stability of anticoagulant derivatives of 4-hydroxycoumarin. II. Structure of the principal degradation products of phenprocoumin, Clocoumarol, warfarin and acenocoumarin].

1978 • 2 citations