Extinction of Cocaine Self-Administration Produces a Differential Time-Related Regulation of Proenkephalin Gene Expression in Rat Brain

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine

1987 • 2,189 citations

Cellular and Molecular Mechanisms of Drug Dependence

1988 • 2,094 citations

Limbic Activation During Cue-Induced Cocaine Craving

1999 • 1,518 citations

Acute Effects of Cocaine on Human Brain Activity and Emotion

1997 • 1,263 citations

A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants

1997 • 1,234 citations

New perspectives in basal forebrain organization of special relevance for neuropsychiatric disorders: The striatopallidal, amygdaloid, and corticopetal components of substantia innominata

1988 • 1,209 citations

Catecholamine innervation of the basal forebrain IV. Topography of the dopamine projection to the basal forebrain and neostriatum

1978 • 1,160 citations

The dopamine hypothesis of the reinforcing properties of cocaine

1991 • 990 citations

The dopamine hypothesis of reward: past and current status

1999 • 981 citations

Activation of memory circuits during cue-elicited cocaine craving.

1996 • 939 citations

Central Catecholamine Neuron Systems: Anatomy and Physiology of the Dopamine Systems

1978 • 920 citations

Mesencephalic dopamine neurons regulate the expression of neuropeptide mRNAs in the rat forebrain.

1986 • 744 citations

Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments

1994 • 549 citations

Marked inhibition of mesolimbic dopamine release: a common feature of ethanol, morphine, cocaine and amphetamine abstinence in rats

1992 • 525 citations

Cocaine self-administration in dopamine-transporter knockout mice

1998 • 523 citations

Regional concentrations of noradrenaline and dopamine in rat brain

1976 • 518 citations

Studies on the distinction between uptake inhibition and release of [3H]dopamine in rat brain tissue slices

1975 • 473 citations

Limbic-striatal interactions in reward-related processes

1989 • 463 citations

Conditioned responses to cocaine-related stimuli in cocaine abuse patients

1992 • 457 citations

Efferents and afferents of the ventral tegmental-A10 region studied after local injection of [3H]leucine and horseradish peroxidase

1979 • 405 citations

Localization of preproenkephalin mRNA in the rat brain and spinal cord by in situ hybridization

1987 • 345 citations

Molecular alterations in the neostriatum of human cocaine addicts

1993 • 326 citations

Inhibition of the uptake of tritiated 5-hydroxytryptamine in brain tissue

1969 • 321 citations

Effects of the dopamine D-1 antagonist SCH 23390 microinjected into the accumbens, amygdala or striatum on cocaine self-administration in the rat

1995 • 293 citations

Differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the rat

1997 • 282 citations

Network-Level Changes in Expression of Inducible Fos–Jun Proteins in the Striatum during Chronic Cocaine Treatment and Withdrawal

1996 • 274 citations

Repeated cocaine administration upregulates K and μ, but not δ, opioid receptors

1994 • 230 citations

Dopaminergic antagonism within the nucleus accumbens or the amygdala produces differential effects on intravenous cocaine self-administration under fixed and progressive ratio schedules of reinforcement

1993 • 214 citations

Cocaine induced secretion of ACTH, beta-endorphin, and corticosterone

1987 • 212 citations

‘Binge’ cocaine administration induces a sustained increase of prodynorphin mRNA in rat caudate-putamen

1993 • 211 citations

Cocaine self-administration differentially alters mRNA expression of striatal peptides

1992 • 201 citations

Cocaine self-administration increases preprodynorphin, but not c-fos, mRNA in rat striatum

1993 • 170 citations

Cocaine selectively increases striatonigral dynorphin levels by a dopaminergic mechanism.

1989 • 169 citations

Neurochemical changes in cocaine withdrawal

1996 • 160 citations

EFFECTS OF MESOLIMBIC DOPAMINE DEPLETION ON RESPONDING MAINTAINED BY COCAINE AND FOOD

1994 • 153 citations

Chronic cocaine alters brain mu opioid receptors

1992 • 151 citations

Cellular responses to chronic treatment with drugs of abuse.

1993 • 138 citations

Cocaine-induced paranoia and psychosis proneness

1991 • 135 citations

Two discrete nucleus accumbens projection areas differentially mediate cocaine self-administration in the rat

1993 • 130 citations

Effects of cocaine on extrapyramidal and limbic dynorphin systems.

1990 • 111 citations

Regulation of kappa opioid receptor mRNA in the rat brain by ‘binge’ pattern cocaine administration and correlation with preprodynorphin mRNA

1996 • 111 citations

Quantitation of preproenkephalin mRNA levels in brain regions from male Fischer rats following chronic cocaine treatment using a recently developed solution hybridization assay

1992 • 110 citations

Cocaine alters opiate receptor binding in critical brain reward regions

1989 • 109 citations

Amygdala dopamine levels are markedly elevated after self- but not passive-administration of cocaine

1994 • 103 citations

Cocaine binges differentially alter striatal preprodynorphin and zif/268 mRNAs

1995 • 100 citations

Effects of excitotoxic lesions of the central amygdaloid nucleus on the potentiation of reward-related stimuli by intra-accumbens amphetamine.

1996 • 96 citations

NAC-1, a Rat Brain mRNA, Is Increased in the Nucleus Accumbens Three Weeks after Chronic Cocaine Self-Administration

1997 • 90 citations

Rat brain neurotransmitter turnover rates altered during withdrawal from chronic cocaine administration

1995 • 84 citations

Effects of excitotoxic lesions of the central amygdaloid nucleus on the potentiation of reward-related stimuli by intra-accumbens amphetamine.

1996 • 78 citations

In vivo Amygdala Dopamine Levels Modulate Cocaine Self‐administration Behaviour in the Rat: D1 Dopamine Receptor Involvement

1997 • 73 citations

Prodynorphin, proenkephalin and κ opioid receptor mRNA responses to acute “binge” cocaine

1997 • 67 citations

Cocaine withdrawal produces behavioral disruptions in rats

1987 • 67 citations

Cocaine: effect of in vivo administration on synaptosomal uptake of norepinephrine

1980 • 58 citations

Importance of Behavioral Controls in the Analysis of Ongoing Events

1992 • 25 citations

Long-term Cocaine Self-Administration Decreases Striatal Preproenkephalin mRNA in Rhesus Monkeys

1997 • 23 citations

Catecholamine sulfates: End products or metabolic intermediates?

1987 • 20 citations

Discriminative stimulus effects of cocaine: Antagonism by dopamine D1 receptor blockade in the amygdala

1995 • 19 citations

Cardiovascular effects of cocaine during operant cocaine self-administration

1996 • 17 citations

Effects of continuous cocaine administration on schedule-controlled behavior in rhesus monkeys

1991 • 12 citations

Acute and repeated ECS treatment increases CRF, POMC and PENK gene expression in selected regions of the rat hypothalamus

1998 • 11 citations

Neurochemical changes in cocaine withdrawal

1996 • 10 citations

Neurobiological Substrates of Drug Self-Administration

1986 • 9 citations

Basic Pharmacological Mechanisms of Cocaine

1998 • 4 citations