Anandamide stimulates phospholipase D activity in PC12 cells but not in NIH 3T3 fibroblasts

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

1992 • 5,504 citations

Molecular characterization of a peripheral receptor for cannabinoids

1993 • 4,950 citations

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

1990 • 4,933 citations

Phospholipase D: a Downstream Effector of ARF in Granulocytes

1994 • 636 citations

Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide.

1995 • 625 citations

Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction.

1993 • 469 citations

N-Acylated glycerophospholipids and their derivatives

1990 • 445 citations

Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles.

1996 • 380 citations

Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells

1993 • 356 citations

Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes

1995 • 353 citations

Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat

1996 • 334 citations

Partial Purification and Characterization of the Porcine Brain Enzyme Hydrolyzing and Synthesizing Anandamide

1995 • 305 citations

Anandamide, a Brain Endogenous Compound, Interacts Specifically with Cannabinoid Receptors and Inhibits Adenylate Cyclase

1993 • 297 citations

Signal transduction and membrane traffic: The PITP/phosphoinositide connection

1995 • 261 citations

Regulation of protein kinase C and role in cancer biology

1994 • 258 citations

Phospholipase D Stimulates Release of Nascent Secretory Vesicles from the trans-Golgi Network

1997 • 251 citations

Dual Activation and Inhibition of Adenylyl Cyclase by Cannabinoid Receptor Agonists: Evidence for Agonist-Specific Trafficking of Intracellular Responses

1998 • 211 citations

The peripheral cannabinoid receptor: adenylate cyclase inhibition and G protein coupling

1995 • 208 citations

Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A.

1995 • 193 citations

The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling.

1995 • 192 citations

SR 141716A Acts as an Inverse Agonist to Increase Neuronal Voltage-Dependent Ca²⁺Currents by Reversal of Tonic CB1 Cannabinoid Receptor Activity

1998 • 180 citations

The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide

1995 • 175 citations

ARF signaling: A potential role for phospholipase D in membrane traffic

1993 • 161 citations

The N-acylation-phosphodiesterase pathway and cell signalling

1996 • 157 citations

Phorbol Ester Stimulates the Hydrolysis of Phosphatidylethanolamine in Leukemic HL-60, NIH 3T3, and Baby Hamster Kidney Cells

1989 • 140 citations

Phospholipase D

1998 • 104 citations

Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells

1998 • 100 citations

The endogenous cannabinoid anandamide is a lipid messenger activating cell growth via a cannabinoid receptor‐independent pathway in hematopoietic cell lines

1998 • 81 citations

Regulation of phospholipase D by protein kinase C

1996 • 75 citations

Phospholipase participation in cannabinoid-induced release of free arachidonic acid

1994 • 58 citations

Production of 1,2‐Diacylglycerol in PC12 Cells by Nerve Growth Factor and Basic Fibroblast Growth Factor

1990 • 57 citations

Hydrogen Peroxide Regulates Phospholipase D-Mediated Hydrolysis of Phosphatidylethanolamine and Phosphatidylcholine by Different Mechanisms in NIH 3T3 Fibroblasts

1994 • 52 citations

Regulation of phospholipase D by sphingosine involves both protein kinase C-dependent and -independent mechanisms in NIH 3T3 fibroblasts

1992 • 37 citations

Protein Kinase Cα Is a Major Mediator of the Stimulatory Effect of Phorbol Ester on Phospholipase D-mediated Hydrolysis of Phosphatidylethanolamine

1996 • 37 citations

Anandamide, a naturally-occurring agonist of the cannabinoid receptor, blocks adenylate cyclase at the frog neuromuscular junction

1994 • 32 citations

Lack of Phospholipase D Activity in Chromaffin Cells: Bradykinin‐Stimulated Phosphatidic Acid Formation Involves Phospholipase C in Chromaffin Cells but Phospholipase D in PC12 Cells

1991 • 29 citations

Ethanol potentiates the stimulatory effects of phorbol ester, sphingosine and 4‐hydroxynonenal on the hydrolysis of phosphatidylethanolamine in NIH 3T3 cells

1991 • 26 citations

Anandamide—a new look on fatty acid ethanolamides

1996 • 19 citations

Bradykinin and Phorbol Dibutyrate Activate Phospholipase D in PC12 Cells by Different Mechanisms

1992 • 14 citations

Wortmannin has opposite effects on phorbol ester‐induced DNA synthesis and phosphatidylcholine hydrolysis

1995 • 13 citations