Optimization of oligonucleotide-based DNA microarrays

Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring

1999 • 11,586 citations

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

2001 • 9,275 citations

Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays

1999 • 4,195 citations

Minimum information about a microarray experiment (MIAME)—toward standards for microarray data

2001 • 4,058 citations

Expression monitoring by hybridization to high-density oligonucleotide arrays

1996 • 2,796 citations

Dissecting the Regulatory Circuitry of a Eukaryotic Genome

1998 • 1,660 citations

Gene Expression Profile of Aging and Its Retardation by Caloric Restriction

1999 • 1,483 citations

A genomic view of alternative splicing

2002 • 1,307 citations

Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer

2001 • 1,297 citations

Molecular cloning (2nd Ed)

1989 • 1,191 citations

Genome-wide expression monitoring in Saccharomyces cerevisiae

1997 • 990 citations

Molecular interactions on microarrays

1999 • 788 citations

DNA microarrays in drug discovery and development

1999 • 662 citations

Resequencing and mutational analysis using oligonucleotide microarrays

1999 • 517 citations

Molecular profiling of human cancer

2000 • 451 citations

Experimental annotation of the human genome using microarray technology

2001 • 446 citations

Gene expression informatics —it's all in your mine

1999 • 406 citations

Biomedical Discovery with DNA Arrays

2000 • 362 citations

Global gene expression analysis of gastric cancer by oligonucleotide microarrays.

2002 • 346 citations

Gene expression microarray analysis in cancer biology, pharmacology, and drug development: progress and potential22Abbreviations: ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; Cy, Cyanine; DLCL, diffuse large cell lymphoma; dNTPs, deoxyribonucleotides; ESTs, expressed sequence tags; mRNA, messenger RNA; NHL, non-Hodgkin’s lymphoma; ORF, open reading frame; RT-PCR, reverse transcription-polymerase chain reaction; and 17AAG, 17-allylamino,17-demethoxygeldanamycin.

2001 • 185 citations

Expression profiling: DNA arrays in many guises

1999 • 125 citations

DNA microarrays and beyond: completing the journey from tissue to cell

2001 • 124 citations

Predicting Splice Variant from DNA Chip Expression Data

2001 • 121 citations

Assessment of the relationship between signal intensities and transcript concentration for Affymetrix GeneChip®arrays

2001 • 103 citations

Expressing what's on your mind: DNA arrays and the brain

2001 • 99 citations

Sequence analysis by hybridization with oligonucleotide microchip: identification of β-thalassemia mutations

1997 • 92 citations

Fabrication of DNA Microarrays Using Unmodified Oligonucleotide Probes

2001 • 90 citations

Gene expression microarrays and the integration of biological knowledge

2001 • 75 citations

DNA microarrays for expression profiling

2001 • 63 citations

Detection of single nucleotide polymorphisms of the human mu opioid receptor gene by hybridization or single nucleotide extension on custom oligonucleotide gelpad microchips: Potential in studies of addiction

2000 • 62 citations

A novel medium throughput quantitative competitive PCR technology to simultaneously measure mRNA levels from multiple genes

2002 • 17 citations