The pharmacology of neurosteroidogenesis

Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding.

1977 • 1,246 citations

Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors.

1983 • 631 citations

Neurosteroids: A new brain function?

1990 • 526 citations

Neurosteroids act on recombinant human GABAA receptors

1990 • 515 citations

Characterization of peripheral-type benzodiazepine binding sites in brain using [3H]Ro 5-4864.

1982 • 384 citations

The peripheral-type benzodiazepine receptor is functionally linked to Leydig cell steroidogenesis.

1990 • 344 citations

Peripheral benzodiazepine binding sites: Effect of PK 11195, 1-(2-chlorophenyl)-n-methyl-n-(1-methylpropyl)-3-isoquinolinecarboxamide

1983 • 342 citations

Influence of recombinant gamma-aminobutyric acid-A receptor subunit composition on the action of allosteric modulators of gamma-aminobutyric acid-gated Cl- currents.

1991 • 338 citations

Peripheral-type benzodiazepine receptors: autoradiographic localization in whole-body sections of neonatal rats.

1985 • 249 citations

Mitochondrial benzodiazepine receptors regulate steroid biosynthesis.

1989 • 246 citations

Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: regulation by a mitochondrial diazepam binding inhibitor receptor.

1992 • 226 citations

Evidence that the cycloheximide-sensitive site of adrenocorticotropic hormone action is in the mitochondrion. Changes in pregnenolone formation, cholesterol content, and the electron paramagnetic resonance spectra of cytochrome P-450.

1978 • 215 citations

Molecular Cloning and Expression of cDNA Encoding a Peripheral-type Benzodiazepine Receptor

1989 • 208 citations

Diazepam Binding Inhibitor and Its Processing Products Stimulate Mitochondrial Steroid Biosynthesis via an Interaction with Mitochondrial Benzodiazepine Receptors^*

1991 • 203 citations

2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR).

1992 • 155 citations

Cloning and expression of cDNA for human diazepam binding inhibitor, a natural ligand of an allosteric regulatory site of the gamma-aminobutyric acid type A receptor.

1986 • 150 citations

Imidazopyridines as a tool for the characterization of benzodiazepine receptors: A proposal for a pharmacological classification as omega receptor subtypes

1988 • 146 citations

Does neurosteroid modulatory efficacy depend on GABAA receptor subunit composition?

1993 • 140 citations

Stimulation of Brain Pregnenolone Synthesis by Mitochondrial Diazepam Binding Inhibitor Receptor Ligands In Vivo

1993 • 129 citations

Putative diazepam binding inhibitor peptide: cDNA clones from rat.

1986 • 127 citations

Neuropeptide modulation of GABA receptor Cl− channels

1985 • 83 citations

Characterization of ligand binding to mitochondrial benzodiazepine receptors.

1989 • 77 citations

Stimulation of brain steroidogenesis by 2-aryl-indole-3-acetamide derivatives acting at the mitochondrial diazepam-binding inhibitor receptor complex.

1993 • 75 citations

Diazepam-binding inhibitor (DBI)-processing products, acting at the mitochondrial DBI receptor, mediate adrenocorticotropic hormone-induced steroidogenesis in rat adrenal gland.

1992 • 57 citations

Participation of mitochondrial diazepam binding inhibitor receptors in the anticonflict, antineophobic and anticonvulsant action of 2-aryl-3-indoleacetamide and imidazopyridine derivatives.

1993 • 55 citations

Role of DBI in brain and its posttranslational processing products in normal and abnormal behavior

1991 • 49 citations

Stereoselective inhibition of the binding of [3H]PK 11195 to peripheral-type benzodiazepine binding sites by a quinolinepropanamide derivative

1986 • 36 citations