Evidence that the cycloheximide-sensitive site of adrenocorticotropic hormone action is in the mitochondrion. Changes in pregnenolone formation, cholesterol content, and the electron paramagnetic resonance spectra of cytochrome P-450.

Lipoprotein-mediated regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesteryl ester metabolism in the adrenal gland of the rat.

1977 • 207 citations

Regulation of sterol synthesis in 15 tissues of rat. II. Role of rat and human high and low density plasma lipoproteins and of rat chylomicron remnants.

1977 • 195 citations

Isolated adrenal cells: Steroidogenesis and cyclic AMP accumulation in response to ACTH

1972 • 178 citations

The Mechanism of Action of Adrenocorticotropic Hormone

1974 • 162 citations

The Effect of Ether Anaesthesia Stress on Cholesterol‐Side‐Chain Cleavage and Cytochrome P450 in Rat‐Adrenal Mitochondria

1972 • 160 citations

On the Mechanism of Action of the Adrenocorticotrophic Hormone

1970 • 158 citations

Spectral Properties of Rat Adrenal‐Mitochondrial Cytochrome P‐450

1974 • 141 citations

Purification and Control of Bovine Adrenal Cortical Cholesterol Ester Hydrolase and Evidence for the Activation of the Enzyme by a Phosphorylation

1977 • 116 citations

EFFECT OF ACTH ON ADRENAL MITOCHONDRIAL CYTOCHROME P‐450 IN THE RAT*

1973 • 104 citations

The Effect of Stress Induced by Ether Anaesthesia on Cholesterol Content and Cholesteryl‐Esterase Activity in Rat‐Adrenal Cortex

1973 • 95 citations

THE DETECTION OF DIFFERENT STATES OF THE P‐450 CYTOCHROMES IN ADRENAL MITOCHONDRIA; CHANGES INDUCED BY ACTH

1973 • 90 citations

Effect of acth on cholesterol side-chain cleavage in rat adrenal mitochondria

1972 • 87 citations

Kinetics and dose—response characteristics of adenosine 3′,5′‐monophosphate production by isolated rat adrenal cells stimulated with adrenocorticotrophic hormone

1972 • 61 citations

Further Studies on the Submitochondrial Localization of Cholesterol Side Chain-cleaving Enzyme System in Hog Adrenal Cortex by Sonic Treatment*

1970 • 47 citations

THE IN VIVO EFFECT OF ACTH ON UTILIZATION OF REDUCING ENERGY FOR PREGNENOLONE SYNTHESIS BY ADRENAL MITOCHONDRIA*

1973 • 46 citations

Cytochrome P-450 of bovine adrenal mitochondria. Ligand binding to two forms resolved by EPR spectroscopy.

1976 • 44 citations

Adrenal Mitochondrial Cytochrome P-450 and Cholesterol Side Chain Cleavage Activity

1973 • 40 citations

Electron paramagnetic resonance studies of cytochrome P-450 and adrenal ferredoxin in single whole rat adrenal glands. Effect of corticotropin

1976 • 39 citations

The acute action of adrenocorticotropic hormone on adrenal steroidogenesis

1974 • 38 citations

Effect of Calcium Ions on Steroid‐Binding Spectra and Pregnenolone Formation in Rat–Adrenal Mitochondria

1974 • 35 citations

Effect of calcium(ion) uptake by rat adrenal mitochondrial on pregnenolone formation and spectral properties of cytochrome P-450

1975 • 33 citations

Spin state changes in cytochrome P‐450 associated with cholesterol side chain cleavage in bovine adrenal cortex mitochondria

1971 • 33 citations

CONTROL OF SUBSTRATE FLUX AND ADRENAL CYTOCHROME P‐450*

1973 • 29 citations

Effect of calcium on pregnenolone formation and cytochrome P-450 in rat adrenal mitochondria

1975 • 29 citations

The effect of calcium ions on the metabolism of exogenous cholesterol by rat adrenal mitochondria

1976 • 27 citations

On the requirement for protein synthesis during corticotropin-induced stimulation of cholesterol side chain cleavage in rat adrenal mitochondrial and solubilized desmolase preparations

1977 • 26 citations

Electron paramagnetic resonance spectra of mitochondrial and microsomal cytochrome P-450 from the rat adrenal

1976 • 20 citations

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