Role of Salt Bridge Formation in Antigen-Antibody Interaction

Rapid measurement of binding constants and heats of binding using a new titration calorimeter

1989 • 2,603 citations

Principles of protein-protein interactions.

1996 • 2,594 citations

Coupling of Local Folding to Site-Specific Binding of Proteins to DNA

1994 • 1,382 citations

Conformations of immunoglobulin hypervariable regions

1989 • 1,165 citations

The Antigenic Structure of Proteins: A Reappraisal

1984 • 957 citations

Anatomy of the antibody molecule

1994 • 868 citations

Temperature dependence of the hydrophobic interaction in protein folding.

1986 • 865 citations

ANTIBODY-ANTIGEN COMPLEXES

1990 • 853 citations

A structural taxonomy of DNA-binding domains

1991 • 615 citations

Interactions of protein antigens with antibodies.

1996 • 543 citations

Contribution of Hydration to Protein Folding Thermodynamics

1993 • 474 citations

Bound water molecules and conformational stabilization help mediate an antigen-antibody association.

1994 • 471 citations

Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex.

1989 • 456 citations

Common Features of Protein Unfolding and Dissolution of Hydrophobic Compounds

1990 • 435 citations

Contribution of Hydration to Protein Folding Thermodynamics

1993 • 419 citations

On the attribution of binding energy in antigen-antibody complexes McPC 603, D1.3, and HyHEL-5

1989 • 367 citations

21 Vertebrate Lysozymes

1972 • 358 citations

Three‐dimensional structure of a fluorescein–Fab complex crystallized in 2‐methyl‐2,4‐pentanediol

1989 • 229 citations

Thermodynamic analysis of an antibody functional epitope

1993 • 169 citations

New algorithm to model protein-protein recognition based on surface complementarity

1992 • 152 citations

Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1

1994 • 149 citations

Enthalpy of hydrogen bond formation in aprotein-ligand binding reaction.

1994 • 135 citations

Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex.

1993 • 132 citations

Electrostatic fields in antibodies and antibody/antigen complexes

1992 • 99 citations

Dissection of Protein–Carbohydrate Interactions in Mutant Hen Egg-white Lysozyme Complexes and their Hydrolytic Activity

1995 • 98 citations

Molecular Recognition of a Salmonella Trisaccharide Epitope by Monoclonal Antibody Se155-4

1994 • 89 citations

Ligand binding: proteinase-protein inhibitor interactions

1991 • 89 citations

Sensitive titration microcalorimetric study of the binding of Salmonella O‐antigenic oligosaccharides by a monoclonal antibody

1991 • 89 citations

Configurational effects in antibody–antigen interactions studied by microcalorimetry

1995 • 80 citations

Protein antigenicity: A thermodynamic approach

1991 • 78 citations

Thermodynamics of Antigen-antibody Binding using Specific Anti-lysozyme Antibodies

1995 • 77 citations

Role of Tyr Residues in the Contact Region of Anti-lysozyme Monoclonal Antibody HyHEL10 for Antigen Binding

1995 • 71 citations

Probing the combining site of an anti-carbohydrate antibody by saturation-mutagenesis: Role of the heavy-chain CDR3 residues

1993 • 60 citations

A three-dimensional model of an anti-lysozyme antibody

1987 • 55 citations

Effect of the Order of Antibody Variable Regions on the Expression of the Single-Chain HyHEL10 Fv Fragment in Escherichia coli and the Thermodynamic Analysis of Its Antigen-Binding Properties

1994 • 53 citations

Effects of substitutions of closely related amino acids at the contact surface in an antigen-antibody complex on thermodynamic parameters

1993 • 52 citations

Contribution to antibody-antigen interaction of structurally perturbed antigenic residues upon antibody binding.

1994 • 51 citations

The Affinity Maturation of Anti-4-hydroxy-3-nitrophenylacetyl Mouse Monoclonal Antibody

1995 • 44 citations

Enthalpy of Antibody-Cytochrome c Binding

1995 • 43 citations

Synthesis and expression of a DNA encoding the Fv domain of an anti-lysozyme monoclonal antibody, HyHEL10, in Streptomyces lividans

1993 • 35 citations