Detection and quantification of adducts formed upon interaction of diamminedichloroplatinum (II) with DNA, by anion-exchange chromatography after enzymatic degradation

The Mechanism of Action of Antitumor Platinum Compounds

1979 • 408 citations

DNA cross-linking as an indicator of sensitivity and resistance of mouse L1210 leukemia to cis-diamminedichloroplatinum(II) and L-phenylalanine mustard.

1981 • 213 citations

Thermal enhancement of DNA damage in mammalian cells treated with cis-diamminedichloroplatinum(II).

1980 • 172 citations

Use of exonuclease III to determine the site of stable lesions in defined sequences of DNA: the cyclobutane pyrimidine dimer and cis and trans dichlorodiammine platinum II examples

1981 • 144 citations

Inhibition of the BamHI cleavage and unwinding of pBR322 deoxyribonucleic acid by the antitumor drug cis-dichlorodiammineplatinum(II)

1981 • 138 citations

Effect of cis -Platinum(II)Diamminodichloride on Wild Type and Deoxyribonucleic Acid Repair-Deficient Mutants of Escherichia coli

1973 • 137 citations

Base-pair substitution hotspots in GAG and GCG nucleotide sequences in Escherichia coli K-12 induced by cis-diamminedichloroplatinum (II).

1981 • 125 citations

Interaction of cis-[Pt(NH3)2(H2O)2](NO3)2 with ribose and deoxyribose diguanosine phosphates

1982 • 109 citations

The interaction of platinum II compounds with bacteriophages T7 and R17

1972 • 97 citations

DNA-platinum interactions in vitro with trans- and cis- Pt(NH3)2Cl2

1975 • 91 citations

Resolution of α, β and γ DNA of Saccharomyces cerevisiae with the antitumor drug cis-Pt(NH3)2Cl2. Evidence for preferential drug binding by GpG sequences of DNA

1976 • 88 citations

Comparative studies of DNA cross-linking and cytotoxicity in Burkitt's lymphoma cell lines treated with cis-diamminedichloroplatinum(II) and L-phenylalanine mustard.

1982 • 45 citations

Preliminary characterization of the adducts formed between the antitumor compound cis-Pt(NH3)2Cl2 and DNA

1982 • 24 citations